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Viral carcinogenesis and genomic instability
2006Oncogenes encoded by human tumor viruses play integral roles in the viral conquest of the host cell by subverting crucial and relatively non-redundant regulatory circuits that regulate cellular proliferation, differentiation, apoptosis and life span. Human tumor virus oncoproteins can also disrupt pathways that are necessary for the maintenance of the ...
Hiroyuki Hayakawa+5 more
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Computer, 2012
The advent of low-cost, large-scale DNA synthesis, coupled with advanced algorithmic tools, opens the door to a host of exciting new biotechnology applications, including vaccines.
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The advent of low-cost, large-scale DNA synthesis, coupled with advanced algorithmic tools, opens the door to a host of exciting new biotechnology applications, including vaccines.
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The viral genome in transformed cells
Proceedings of the Royal Society of London. Series B. Biological Sciences, 1971Polyoma and SV 40-transformed cells carry multiple copies of the entire genome in their chromosomes; the viral DNA sequences appear to be covalently integrated into the host cell’s DNA but it is not known whether they are clustered in a reiterated tandem sequence or whether they are distributed singly or in clusters throughout the cell’s chromosomes ...
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The Epstein-Barr virus (EBV) genetic map underpins all our understanding of the virus biology and its role in disease. EBV was the first large DNA virus to be fully sequenced and this has been followed by many years of detailed mapping of viral genes and other genetic elements. The genetic map of EBV is based on the reference NC_007605 virus genome but
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1985
All characterized members of the Bromoviruses, Cucumoviruses, Ilarviruses, and also alfalfa mosaic virus (AMV) contain a tripartite genome in that the three largest of the four major encapsidated RNAs are required for infectivity. The Ilarviruses and AMV are distinguished from the two other virus groups by the additional requirement for infection of ...
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All characterized members of the Bromoviruses, Cucumoviruses, Ilarviruses, and also alfalfa mosaic virus (AMV) contain a tripartite genome in that the three largest of the four major encapsidated RNAs are required for infectivity. The Ilarviruses and AMV are distinguished from the two other virus groups by the additional requirement for infection of ...
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Structure of Plant Viral Genomes
1980Until two years ago, the subject matter of an article such as this, would have been restricted to plant viral RNA’s. Indeed nothing or very little was know about the Organization of plant viral DNA genomes. With the recent determination of the complete sequence of cauliflower mosaic virus (CaMV) DNA, the Situation was altered, and since these data ...
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Viral and host heterogeneity and their effects on the viral life cycle
Nature Reviews Microbiology, 2021Jennifer E Jones+2 more
exaly
Transactions of the American Microscopical Society, 1972
John O. Cobliss+2 more
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John O. Cobliss+2 more
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