Results 111 to 120 of about 42,684,660 (287)
Advanced ScienceMany cancer risk variants are located within enhancer regions and lack sufficient molecular interpretation. Here, we constructed the first comprehensive atlas of enhancer RNA (eRNA)‐mediated genetic effects from 28 033 RNA sequencing samples across 11 ...
Wenyan Chen, Zeyang Wang, Yinuo Wang, Jianxiang Lin, Shuxin Chen, Hui Chen, Xuelian Ma, Xudong Zou, Xing Li, Yangmei Qin, Kewei Xiong, Xixian Ma, Qi Liao, Yunbo Qiao, Lei Li +14 more
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Journal of the American Society for Horticultural ScienceSweet corn ranks among the top vegetable crops by production value in the United States. The sweetness, tenderness, and texture of sweet corn kernels are the most important traits for eating quality.
Lillian M. Hislop, Matheus Baseggio, Alexa R. Wilson, Auden Parkinson, Carl Branch, Cathleen A. McCluskey, Patrick Flannery, Michael A. Gore, William F. Tracy +8 more
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eLife, 2018 Uterine leiomyomas (ULs) are benign tumors that are a major burden to women’s health. A genome-wide association study on 15,453 UL cases and 392,628 controls was performed, followed by replication of the genomic risk in six cohorts.
Niko Välimäki, Heli Kuisma, Annukka Pasanen, Oskari Heikinheimo, Jari Sjöberg, Ralf Bützow, Nanna Sarvilinna, Hanna-Riikka Heinonen, Jaana Tolvanen, Simona Bramante, Tomas Tanskanen, Juha Auvinen, Outi Uimari, Amjad Alkodsi, Rainer Lehtonen, Eevi Kaasinen, Kimmo Palin, Lauri A Aaltonen +17 more
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Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger +2 more
wiley +1 more source
Genome-wide association and functional follow-up reveals new loci for kidney function [PDF]
, 2012 Chronic kidney disease (CKD) is an important public health problem with a genetic component. We performed genome-wide association studies in up to 130,600 European ancestry participants overall, and stratified for key CKD risk factors. We uncovered 6 new
Döring, Angela, Atkinson, Elizabeth J, Gary C Curhan, Wichmann HE, Thun, G.-A., Trompet, S., Heid, I. M., Goessling Wolfram, Kroemer H.K., Boerwinkle, E., Kähönen M., Wilson J.F., Franke A., Biffar Reiner, Palmer, C., Zemunik T, Toshiko Tanaka, Rettig Rainer, Rao, Madhumathi, Toniolo, D. (Daniela), Smith, AV, Liu C.-T., Harshal Deshmukh, Curhan, G. C., Foster, Meredith C, Taliun, D, Heid Iris M., Gao, XY, Ridker P., Glazer, N., Fox Caroline S., Liu, Ching-Ti, Struchalin, M.V. (Maksim), Trompet, S. (Stella), O´Connell, J.R., Böger C.A., Chu, A.Y., de Andrade M, Smith AV, Fuchsberger Christian, Krämer, B.K., Hwang, S. J., Atkinson, Elizabeth J., Igl, W., Harris, T.B. (Tamara), Jingzhong Ding, Turner ST, Vollenweider Peter, Voelker, Uwe, Adrienne Tin (160761), Toniolo, D, J. Wouter Jukema (127361), Johnson, A.D. (Andrew), Vincent Chouraki, Uitterlinden A.G., Gorski, M. (Mathias), Adam M, Andrews JS, Rivadeneira, F, Turner, S. T., Wheeler, H.E., Gyllensten, Ulf,, Turner, ST, Rao M, Henry Völzke (64286), Meredith C. Foster (165430), Tin, A., Florian Kronenberg (87557), Andrews, J.S. (Jeanette), Nikopensius, Tiit, Shuldiner AR, Rudan, I. (Igor), Jie Jin Wang (103779), Borecki, I, Freedman, BI, Portas L, Ulivi, S, Nauck, Matthias, et al., Rao Madhumathi, Smith, A.V. (Albert Vernon), Stumvoll Michael, Ketkar S, Imboden, Medea, Peter P. Pramstaller (150111), Trompet S., Gudny Eiriksdottir (8872), Doney, A., Hastie N., Karlhans Endlich, Illig T, Vitart, Veronique, Homuth, G. (Georg), Rao M., Johansson, Åsa,, Kolcic, I. (Ivana), O'Seaghdha, Conall, Kähönen, M., Ketkar, S, Cavalieri, M., Probst-Hensch, NM, Wright, A.F., Gao, X., Deshmukh H, Minelli, Cosetta, Gasparini P., Chu, AY, Ciullo, M., Conall M O'Seaghdha, Ulf Gyllensten, Li, M. (Man), Probst-Hensch, Nicole M., Paulweber, B, Wild, S.H. (Sarah), Robino, A, Atkinson EJ, Rettig R, Buckley, B.M., Dehghan A, Johansson, Å, Illig, T., Yang, Q., Franke, Andre, Wang, J.J. (Jie Jin), Adam M., Biffar R., Colhoun, H., Cornelis MC, Curhan GC, Kolcic Ivana, Thun, G.A., Borecki I, Ding, JZ (Jing Zhong), Tönjes A., Tönjes, A. (Anke), Ding Jingzhong, Iris M Heid, Völzke, H, Kim, SK, Lohman K, Kroemer, H. K., Thun, G. A., Liu, CT, Hofman A, Köttgen, Anna, Qiong Yang, Ferrucci Luigi, Adam Martin, Boban, M., Wright, AF, Aulchenko, Y.S., Mariza de Andrade (31845), Holliday, E.G., Zaboli, G, Ding, Jingzhong, Albert V Smith, Bernhard Paulweber, Probst-Hensch Nicole M., Florian Ernst, Nick Hastie, Luigi Ferrucci (150038), Endlich Karlhans, Stumvoll, M. (Michael), Nicole M Probst-Hensch, Polasek, Ozren, Matthias Nauck, Stuart K. Kim (112150), De Andrade, M, Andrews, Jeanette S., van Duijn, Cornelia M., Anna Köttgen, Ciullo, M, Kao, WHL, Karlhans Endlich (112716), Garnaas Maija, Trompet, Stella, Palmer, Colin; id_orcid, Murgia, Federico, Struchalin, M., Gibson, G., Thor Aspelund, Ozren Polasek (3965693), Chen, M.H., Ching-Ti Liu, Pramstaller, PP, Hwang Shih-Jen, Rettig R., Vollenweider, P, Wilmar Igl, Oostra Ben A., Kovacs P, Afshin Parsa (175121), Coresh, J., Kutalik, Z. (Zoltán), Esko, T. (Tõnu), Fuchsberger, C., Pirastu, M, Cornelis, Marilyn C, Pistis, G, Chouraki, V. (Vincent), Tanaka, T, Haun M., Struchalin Maksim, Thun GA, Mägi, R., Mitchell, Braxton D., Demirkan, A, Köttgen, A., Colhoun H, Deshmukh, H., Liu Y., Launer, L. J., Garnaas M., Heid, I.M. (Iris), Andrade, M. de, Franke, A., Biffar, R., Chasman, D.I. (Daniel), Gyllensten Ulf, Campbell, Harry, Teumer, A. (Alexander), Goessling, W, Man Li (81239), Colin Palmer (165015), Liu, C. T., Ellinghaus, D., Wichmann H.-E., Wang JJ, Feitosa, M.F. (Mary Furlan), Jacqueline C. M. Witteman (175109), Bochud, M., Andrews, J. S., Bergmann, S, Tin Adrienne, O'Seaghdha C.M., Parsa, A., Goessling W, Döring Angela, Li G., Uitterlinden Andre G., Thun G.-A., Hu, Frank B., Portas, Laura, Gorski M, Chasman, DI, Georg Homuth (110202), Kardia, S.L.R., Kronenberg F, Holliday, E. G., Pistis, G. (Giorgio), Fox, C.S., Vilmundur Gudnason, Mitchell, Paul, Freedman Barry I., Doering, Angela, Ruggiero D., Wild S.H., Li, M., Ivana Kolcic, Chu, Audrey Yu-lei, Wilson, J.F., Imboden M, Goessling, W. (Wolfram), Raitakari, O., van Duijn CM, Wolfgang Koenig, Marie Metzger (156894), Chen M.-H., Launer Lenore J., Li M., Ding, J.Z., Schmidt, H., Mladen Boban, Ghazal Zaboli (174959), Ernst, F, Jacobs, Gunnar, Wichmann, HE, Isaacs, A., Kardia, Sharon L. R., Stracke, Sylvia, Trompet Stella, Stuart K Kim, Boban, Mladen, Koenig, W. (Wolfgang), Hwang, S.J., Wilson, James F; id_orcid, Nicole Glazer, Kim S.K., Feitosa M., Kovacs, P, Bergmann, S., Völker, U., Jukema J. Wouter, Rettig, R. (Rainer), Teumer, Alexander, Wright Alan F., Demirkan, A. (Ayşe), Ciullo Marina, Toshiko Tanaka (174638), Illig, T, Cavalieri M., Ming-Huei Chen, Bochud M., Aulchenko, Yurii S., Ute Nöthlings (140098), Toniolo Daniela, Nauck Matthias, Prokopenko, I, Giorgio Pistis, Böger CA, Struchalin, M, Schmidt, R. (Reinhold), Gian-Andri Thun, Kao WH, Hayward C, Colhoun Helen, Paul Mitchell (103717), Guo Li (174860), Cinzia Sala (74631), Siscovick D.S., Kardia, S.L., Gasparini, Paolo, Gudnason Vilmundur, Fox, Caroline, Giulianini F., Kovacs, Peter, Laura Portas (175069), Jacobs G, Parsa, A. (Afshin), Chen Ming-Huei, Reedik Mägi, Hayward, Caroline, Hofman, A. (Albert), Lehtimäki T, Viikari Jorma, Abbas Dehghan (174878), Albert Hofman, Igl, Wilmar, Daniel Taliun, Wild, S. H., Aspelund Thor, Ford, I., Nauck M., CARDIoGRAM Consortium, Kroemer, H.K., Hu Frank B., Heid I.M., Wheeler H.E., O'Seaghdha, Conall M, Coresh, J, Nick Hastie (175020), Tin, Adrienne, Mitchell, P, Schmidt, R., Helena Schmidt (174915), Aspelund, T, Deshmukh, Harshal, Elizabeth G Holliday, Wheeler HE, Oostra, B.A., Pirastu Mario, Stumvoll M, Turner, S.T., Völker U., Glazer N., Mitchell, P., Atkinson E.J., Chu A.Y., Paul Mitchell, Peter Kovacs (103720), Martin Adam (175082), Wilson, JF, Yang Q, Rossella Sorice, Alan R. Shuldiner (110828), Böger, Casten A, Tiit Nikopensius, Ernst Florian, Portas, L., Sorice, R, Taliun Daniel, Nikopensius T., Jukema J.W., Li, G., Metzger M., Cavalieri, M. (Margherita), Cinzia Sala, Zaboli G, Glazer Nicole, Pistis Giorgio, Kao, W. H. Linda, Wilson, J.F. (James), Murgia, F, Foster, M.C., Pattaro C., Wright A.F., Kardia, S.L.R. (Sharon), Andre Franke, Ellinghaus D, Braxton D Mitchell, Yurii S. Aulchenko (148330), Mitchell B.D., Peter Kovacs, Kaehoenen, Mika, Stracke S., Li, G (Guo), Rivadeneira Ramirez, F. (Fernando), Mario Pirastu (175088), Olden M, Ford, I. (Ian), Oostra B.A., Campbell, H. (Harry), Holliday EG, Wichmann, H.-E., Ciullo M, Lenore J. Launer (110269), Hu, F.B., Kao, W.H.L., Buckley, BM, WTCCC2, Gao, X, Thomas Illig (44906), Sala, C, Colhoun, Helen, Van Duijn, CM, Demirkan, A., Bochud, Murielle, Yang Q., Aspelund T, Eiriksdottir, G, Gasparini, P., Nikopensius Tiit, Wang, JJ, Uitterlinden, AG, Illig, T. (Thomas), Homuth G., Tamara B Harris, Deshmukh Harshal, Vitart Veronique, Madhumathi Rao, Chen MH, Haun, Margot, Hundertmark C., Carsten A Böger, Giulianini, F., Chu, Audrey Y, Aspelund, T. (Thor), Andrews Jeanette S., Madhumathi Rao (174925), Margherita Cavalieri (174919), Kronenberg F., Nauck, M., Cosetta Minelli, Campbell, Harry; id_orcid, Metzger Marie, Ferrucci, L. (Luigi), Sharon L R Kardia, Kolcic, I., Wheeler, HE, Kollerits, Barbara, Angela Döring (64291), de Andrade Mariza, Florian Ernst (174614), David Ellinghaus (87596), Liu CT, Ford, Ian, Conall M. O'Seaghdha (174855), Ford I., Colhoun H., Daniela Toniolo, Imboden M., Zemunik T., Shuldiner, A.R., Ingrid Borecki (175089), Kutalik Zoltan, Boerwinkle E., Paulweber Bernhard, Liu Y, Pattaro C, Wild Sarah H., Kovacs Peter, Province, M., Sorice R., Prokopenko, Inga, Hwang S.-J., Bergmann, Sven, Launer, Lenore J., Fox, C. S., Bergmann, S.M. (Sven), Wichmann, H. E., Giulianini Franco, Garnaas, M., Jacobs G., Imboden, M. (Medea), Franke Andre, Parsa A, Magi, Reedik, Liu, C.-T., Esko, T, David S. Siscovick (174822), Gierman Hinco J., David Ellinghaus, Brendan M. Buckley (175076), Buckley Brendan M., Lohman, K, Nikopensius, T, Aulchenko, Y. S., Boban, M, Maija Garnaas, Gunnar Jacobs (174977), Andre G. Uitterlinden (89938), Minelli C., Jukema, J.W., Schmidt, Helena, Ferrucci L., Luigi Ferrucci, Koenig, W, Stumvoll M., Probst-Hensch, N.M., Gyllensten U., Homuth, G., Mika Kähönen, H-Erich Wichmann, Meredith C Foster, Uitterlinden, A. G., Jacobs, Gunar, Andres Metspalu (61760), Sorice, Rossella, Fuchsberger, Christian, Goessling, Wolfram, Curhan Gary C., Coresh J, Haun M, Paolo Gasparini (139832), Laura Portas, Esko Tõnu, Rainer Rettig (112747), Endlich K., Freedman, B.I., Haun, M. (Margot), Polasek, O., Chu AY, Hinco J Gierman, Ayse Demirkan (174933), Endlich, Karlhans, Homuth, Georg, Harris, TB, Nöthlings Ute, Hundertmark, C., Zemunik, T. (Tatijana), Sorice, R., Franke, A. (Andre), O'Connell, J.R., Kollerits B, Jingzhong Ding (165392), Province Michael, Elizabeth J. Atkinson (174866), Li, Guo, Oostra, B.A. (Ben), Gao X, Kao W.H.L., Ruggiero Daniela, Parsa Afshin, Yongmei Liu, Antonietta Robino (149863), Vitart, V, Mitchell, B.D. (Braxton), Fuchsberger C, Raitakari O., Hayward, C, Pramstaller PP, Deshmukh H., Rossella Sorice (140754), Vilmundur Gudnason (8873), Borecki, I.B. (Ingrid), Gyllensten, U. (Ulf), Gorski, M, Eiriksdottir Gudny, Böger, CA, Audrey Y. Chu (174895), W. H. Linda Kao (160779), Helena Schmidt, Probst Hensch NM, Ding J., Igor Rudan, Wichmann, H. -Erich, Siscovick, D.S. (David), Paulweber, Bernhard, O'Seaghdha, C. M., Ferrucci, L., Foster Meredith C., Oostra, B. A., Palmer C., O'Seaghdha, C.M., Marie Metzger, Henry Völzke, Antonietta Robino, Esko T, Alex Doney (175054), Isaacs, A, Tönjes, A, Gudnason V., Lehtimäki, T, Helen Colhoun, Cornelis, Marilyn, Giulianini F, Thun Gian-Andri, Campbell, H, Claudia Hundertmark (174852), Hofman, Bert, Wright, A. F., Kutalik Z., Toniolo, D., Hwang SJ, Eiriksdottir G, Kolcic, I, Ferrucci, Luigi, Teumer A., Johnson A.D., Bernhard K Krämer, Olden, M., Olden, M, Hundertmark Claudia, Michael Stumvoll, Mägi R., Jorma Viikari, Witteman JC, Ulivi, Sheila, Kim, Stuart K., Heid, IM, Fuchsberger, C, Wichmann, H.-Erich, Heyo K Kroemer, Anke Tönjes, Krämer, Bernhard K., Tin A, Hundertmark, Claudia, Siscovick, DS, Struchalin, Maksim, Gao, X.Y., Kollerits, B. (Barbara), Holliday, EG, Gian-Andri Thun (142891), Sven Bergmann, Albert V. Smith (103644), Johansson Åsa, Stella Trompet, Murgia, F., Chen, M. H., Franco Giulianini, Lehtimaeki, Terho, Coresh, J. (Josef), Nothlings, Ute, Olden, M. (Matthias), Michael Province (175044), Demirkan Ayse, Wild, S.H., de Andrade, M., James F Wilson, Eiriksdottir, G., Eric Boerwinkle (36288), Federico Murgia (174898), Bernhard Paulweber (102633), Robino Antonietta, Johnson, AD, Alan F Wright, Metspalu A, Mitchell Paul, Catherine Helmer (175026), Wheeler, Heather E., Medea Imboden (110145), Gorski, M., Probst-Hensch, N. M., Caroline Hayward, Krämer B.K., Harris, Tamara B., Chouraki, Vincent, Trompet S, Giulianini, Franco, Harry Campbell, Ivana Kolcic (3212697), Frank B. Hu (127167), Launer, LJ (Lenore), Demirkan, Ayse, Schmidt, R, Uitterlinden, André; id_orcid, Schmidt, H, Ben A Oostra, Province, Michael, Veronique Vitart, Rivadeneira, F., Helmer, C, Hayward Caroline, Reiner Biffar (135695), Viikari, J, Rudan, Igor, Anna Köttgen (3111024), Mitchell Braxton D., Völzke H, Koenig Wolfgang, Martin Adam, Veronique Vitart (149854), Sylvia Stracke (175001), Turner S.T., Guo Li, Wilson, J. F., Dehghan, A. (Abbas), Smith, A. V., Völzke, H., Freedman, Barry I., Dehghan A., Igl W., Harris Tamara B., Köttgen A., Rettig, R., Chouraki V, Province, M, Ellinghaus David, Tin, A, Palmer, Colin, Jacobs Gunnar, Holliday, E.G. (Elizabeth), Rainer Rettig, Uitterlinden, A.G., Teumer A, Sarah H Wild, Pramstaller P.P., Biffar, R. (Reiner), Ford I, Wheeler, H. E., Nauck, M. (Matthias), Ridker, P.M. (Paul), Polasek Ozren, Adam, M., Kutalik, Z., Ferrucci L, Margherita Cavalieri, Oostra BA, Cornelis, M. (Marilyn), Alan F. Wright (150085), Kolcic, Ivana, Olden Matthias, Goessling, W., Tönjes A, Chouraki Vincent, Raitakari, O. (Olli), Hofman, A, Cavalieri, Margherita, Doney A, Hwang, S.-J., Angela Döring, Rudan, I, Curhan, G.C., Metspalu A., Launer, LJ, Vitart, V., Andrew D Johnson, Thun, GA, Thor Aspelund (103668), Döring, A, Isaacs A, Witteman, J.C.M. (Jacqueline), Christian Fuchsberger, Chen, M-H. (Ming-Huei), O'Connell, Jeffrey R., Hayward, Caroline; id_orcid, Uwe Völker, Vollenweider, P. (Peter), Pattaro, C. (Cristian), Polasek, O, Launer L.J., Michael Stumvoll (103716), Gierman, H.J., Palmer C, Johnson Andrew D., Chouraki, V., Krämer, BK, Ding, J., Caroline Hayward (149856), Paulweber B., Zaboli, Ghazal, Hastie Nick, Rivadeneira F., Mitchell P., Pirastu, Mario, Wang, Jie Jin, Gorski Mathias, Lehtimäki Terho, Nöthlings, U, Igor Rudan (150101), Borecki Ingrid, Shamika Ketkar, Curhan G.C., Illig T., Nicole Glazer (113632), Rao, M, Uitterlinden, Andre G., Rettig, Rainer, Schmidt R., Reinhold Schmidt, Ketkar, Shamika, Heid IM, Stella Trompet (174901), Zoltan Kutalik, Wheeler Heather E., Kronenberg, F. (Florian), Kutalik, Zoltan, Johansson, Asa, Johansson Å, Gasparini, P, Kronenberg, Florian, Elizabeth J Atkinson, Hofman, A., Sarah H. Wild (130180), Smith, Albert V, Schmidt, Reinhold, Palmer, C.N.A. (Colin), Vollenweider P., Doney Alex, Wilson JF, Minelli Cosetta, Ulivi, S. (Shelia), Prokopenko I, Gorski, Mathias, Struchalin M, Ridker, P, Hu FB, Kollerits, B, Heather E Wheeler, Toniolo D., Hofman Albert, Sala, Cinzia, Lehtimäki, Terho, Andres Metspalu, Abbas Dehghan, Kurt Lohman, O'Seaghdha, CM, Mladen Boban (149857), Kähönen Mika, Krämer Bernhard K., Gyllensten, U., Pramstaller, P.P. (Peter Paul), Qiong Yang (28822), Kähönen, M, O'Seaghdha, Conall M., Kurt Lohman (110218), Biffar, R, Thomas Illig, Ghazal Zaboli, Cornelis, Marilyn C., Launer, L.J., Homuth G, Chasman, Daniel I., Sala C, Mägi Reedik, Fernando Rivadeneira, Launer LJ, Zaboli G., de Andrade, Mariza, Shih-Jen Hwang, Jeanette S. Andrews (174941), Marina Ciullo (140763), Ulivi Sheila, Tamara B. Harris (110195), Atkinson Elizabeth J., Holliday, Elizabeth G., Daniel I Chasman, Yang, Qiong, Braxton D. Mitchell (110791), Kollerits Barbara, Gierman, Hinco J, Kovacs, P., Gierman HJ, Atkinson, E. J., Kardia Sharon L. R., Ciullo M., Isaacs, Aaron; id_orcid, Andrews J.S., Duijn, C.M. van, Lohman Kurt, Shih-Jen Hwang (79945), Harris TB, Zemunik Tatijana, Franke, A, Bergmann S, Paul Ridker, Ruggiero, D, Gierman, HJ, Gyllensten, Ulf, Helmer C, Nikopensius T, Franke A, Bochud M, Fuchsberger C., Dehghan, Abbas, Atkinson, EJ, Cristian Pattaro, Minelli C, Caroline S Fox, Schmidt Helena, Pramstaller, P. P., Taliun D., O'Connell, J. R., Demirkan A., van Duijn C.M., James F. Wilson (150146), Böger, C. A., Bergmann S., Palmer Colin, Johnson AD, Wright, A.F. (Alan), Stephen T. Turner (103474), Ching-Ti Liu (100170), Mary Feitosa (165417), Vitart, V. (Veronique), Pistis G., Ridker Paul, Margot Haun, H.-Erich Wichmann (72009), Ian Ford (30666), Harry Campbell (30339), Boban Mladen, Freedman BI, Pirastu M., Ulivi, S., Raitakari, Olli, Krämer BK, Rudan Igor, Rudan, I., Jukema, J. W., Ulivi S., Franco Giulianini (175060), Wilson, James F., Sala, C. (Cinzia), Chu, Audrey Y., Hinco J. Gierman (174862), Ulf Gyllensten (13773), Siscovick, D. S., Stracke, S., Doney, A, Metzger M, Li, Man, Wang, J. J., Illig, Thomas, Tõnu Esko (102379), Döring, A. (Angela), Hu, Frank, Völker Uwe, Mary Feitosa, Igl, W, Chen, M.-H., Koenig W, Adam, M, Vitart V, O'Connell, Jeffrey R, Ketkar S., Imboden Medea, Cosetta Minelli (38846), Johnson, Andrew D., Reiner Biffar, Völzke H., Matthias Olden, Mariza de Andrade, Aulchenko, Y.S. (Yurii), Hwang, Shih-Jen, Jukema JW, Portas L., Hwang, SJ, Polasek, O. (Ozren), Lohman, Kurt, Ford Ian, Wellcome Trust Case Control Consortium 2, Gyllensten, U, Vitart V., Harshal Deshmukh (174893), Freedman B.I., Caroline S. Fox (110474), Yang, Q. (Qiong Fang), Alexander Teumer (112757), Holliday, Elizabeth G, Kao W. H. Linda, Marilyn C. Cornelis (174871), Boger, C.A., Kroemer, H.K. (Heyo), Parsa, Afshin, Kovacs P., Tõnu Esko, Liu Ching-Ti, Dehghan Abbas, Buckley B.M., Jukema, J. Wouter, Haun, M, Anke Tönjes (103703), Johnson, A.D., Afshin Parsa, Ernst F., Vollenweider, P., Völker U, Jeffrey R. O'Connell (170220), Wilson James F. +999 more
core +1 more source
BMC GenomicsBackground Type I hereditary hemochromatosis (HH), caused by pathogenic HFE variants, is among the most common autosomal recessive disorders in Northern Europe.
Miriam Nurm, Tarmo Annilo, Sebastian May-Wilson, Anu Reigo, Reedik Mägi, Urmo Võsa, Neeme Tõnisson, Estonian Biobank Research Team, Toomas Haller +8 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales +11 more
wiley +1 more source
Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function [PDF]
, 2012 Genome-wide association studies have identified numerous genetic loci for spirometic measures of pulmonary function, forced expiratory volume in one second (FEV1), and its ratio to forced vital capacity (FEV1/FVC).
Wenbo Tang (110161), Alisa K. Manning (110227), Heinrich, J (Joachim), Thomas Lumley (57337), Sood, A, R Graham Barr, Brusselle, Guy G., Loth, Daan W, Akshay Sood (71826), O'Connor, George T, Liu, YM, Stephen S. Rich (7634141), Harris, Tamara B, Fornage, Myriam, Alisa K. Manning (7634102), Stephanie J. London (62450), Josée Dupuis (28859), Probst-Hensch, Nicole, Chen, TH, Elliott, Paul, Eiriksdottir, Gudny, Zhai, G., Jason Z. Liu (7634093), Patricia A. Cassano (110298), Hugues Aschard (110171), Joachim Heinrich (60421), Guy G Brusselle, Couper, D. J., Gu, Xiangjun, Uitterlinden, Andre G., Smith, AV, Couper, DJ, Lenore J. Launer (110269), Matthias Wjst (56613), Myriam Fornage (45591), Kritchevsky, S. B., Postma, Dirkje S., Liu, Y, Mirel, D. B., Rurth J.F. Loos (7634099), H. Marike Boezen (7634168), Uitterlinden, André G, Hysi, Pirro G., R. Graham Barr (7634171), Timothy D. Spector (7634159), Glaeser, S, Loos, Ruth J F, Christer Janson, Burkart, Kristin Marie, Heinrich, Joachim, Eiriksdottir, G, Hysi, P., Boezen, H Marike, Zhai, GJ, Liu, Jason, Probst-Hensch, Nicole M, O Dale Williams, George T. O'Connor (110263), Jason Z. Liu (110210), Uitterlinden, AG, Hofman, A., Heckbert, Susan R, David P Strachan, Daan W. Loth (7634072), Louise V. Wain (7588511), Tamara B Harris, Smith, Albert V, Jarvis, Deborah, Imboden, M., Launer, Lenore J, Heckbert, Susan R., Hysi, PG, Morrison, A. C., Marciante, K. D., Rich, Stephen S., Hartikainen, Anna-Liisa, Mirel, Daniel B, Harris, Tamara, Liu, Jason Z, Jarvelin, Marjo-Riitta, Kari E. North (68131), Aldrich, Melinda C., Manning, A. K., Koch, B., Couper, David J., Timothy D Spector, Curjuric, I., Wilk, J. B., Eijgelsheim, Mark, North, Kari E, Louise V Wain, Rivadeneira, F, Williams, O. D., Homuth, G, Marciante, KD, Cassano, P. A., Joanna Smolonska (101730), Susan R. Heckbert (7634165), Strachan, David P., Henry Völzke (64286), Boezen, H. M., Marciante, Kristin D., Jerome I. Rotter (7634114), Ramasamy, A, Alisa K Manning, Lumley, T., Amanda Henry, Daniel B. Mirel (7634153), Mark Eijgelsheim (110185), Bernd Meibohm (110267), Manichaikul, A, Manichaikul, Ani, Amy R Bentley, Daan W Loth, Kristin D. Marciante (110230), Aldrich, Melinda, Zhao, Jing Hua, Hysi, Pirro, Kurt Lohman, Alanna C Morrison, Melinda C. Aldrich (110234), Meibohm, B, O'Connor, George, Imboden, Medea, Gharib, Sina A, Wilk, Jemma B., Gudny Eiriksdottir (8872), Obeidat, Ma’en, Marchini, J, Stricker, Bruno H. C., Kurt Lohman (110218), O. Dale Williams (110242), Stephen B. Kritchevsky (7240181), Alanna C. Morrison (110248), Lenore J Launer, Franceschini, N, Tamara B. Harris (7240184), O’Connor, George T., Probst-Hensch, NM, Maria Soler Artigas (7634069), Launer, Lenore J., Marchini, Jonathan, Dupuis, Josee, Hall, Ian, Loehr, Laura, Nicole M. Probst-Hensch (7634162), Fernando Rivadeneira, Rich, S. S., Sina A. Gharib (63265), Cathy C. Laurie (110245), Kristin D. Marciante (7634105), Hancock, D. B., Stricker, BHC, Tamara B. Harris (110195), Henry, A, Guangju Zhai (110167), Bonnie R. Joubert (110252), Ian P. Hall (7377620), Probst-Hensch, Nicole M., Rotter, Jerome I, Nicholas J Wareham, Vonk, Judith, Dana B. Hancock (110121), R. Graham Barr (109958), Franceschini, Nora, Hammond, Christopher J., Burkart, KM, Bruno H C Stricker, Rochat, Thierry, Rotter, Jerome, Tobin, Martin, Boezen, H. Marike, Loos, Ruth J. F., Artigas, M.S., Loth, Daan W., Josée Dupuis, Medea Imboden, Lohman, K, Hall, I. P., Deborah Jarvis, Wain, Louise V., Guy G. Brusselle (7634108), André G. Uitterlinden (7634138), Loos, RJF, Judith M. Vonk (7634135), George T O'Connor, McArdle, Wendy L., Laurie, Cathy C., Barr, R. Graham, Dupuis, J, Khaw, K. T., Koch, B, Hancock, Dana, Burkart, Kristin, Manning, Alisa K., Tobin, Martin D, Jemma B Wilk, Völzke, H, Paul Elliott, Rochat, T., Artigas, Maria Soler, Boezen, Hendrika, Homuth, G., Patricia A. Cassano (7634174), Stephanie J. London (7634180), Melinda C Aldrich, Gudnason, V, Albert V. Smith (7634078), Bentley, Amy, Pirro G. Hysi (110207), Smith, Albert, Gharib, SA, Rich, Stephen, Albert V Smith, Martin D Tobin, Marjo-Riitta Jarvelin (110290), Dana B. Hancock (7634066), Wareham, N. J., Guy G. Brusselle (110236), Wareham, NJ, Bruce M Psaty, Ani Manichaikul, Smith, Albert V., Anna-Liisa Hartikainen, Nicole M Probst-Hensch, Chen, T-H, Sood, A., Ruth J F Loos, Bentley, Amy R, Gu, X, Jarvelin, MR, Adaikalavan Ramasamy, Daniel B Mirel, Uitterlinden, A., Jing Hua Zhao, Bruno H. C. Stricker (110279), Burkart, Kristen M., Morrison, Alanna, Hall, IP, Psaty, B. M., Meibohm, Bernd, Couper, David, Homuth, Georg, Harris, TB, Heckbert, S. R., Laurie, CC, Chen, T. H., Kritchevsky, Stephen, Mirel, Daniel B., Christopher J Hammond, Akshay Sood, Xiangjun Gu, Daan W. Loth (110140), Wareham, Nicholas J., Obeidat, M, Smolonska, J, Marciante, Kristin, Laurie, C., Psaty, Bruce, Lumley, Thomas, Sven Gläser, André G. Uitterlinden (2213413), Hofman, Albert, Zhao, JH, Jerome I. Rotter (103729), Loehr, Laura R, Yongmei Liu, Myriam Fornage, Cassano, Patricia A, Hartikainen, A. L., Xiangjun Gu (73651), Stricker, Bruno HC, Zhao, J. H., Tang, W, Brusselle, GG, Tang, Wenbo, Voelzke, Henry, Stephen B Kritchevsky, Boezen, Marike, Dana B Hancock, Laurie, Cathy C, London, S. J., Vilmundur Gudnason (8873), Strachan, DP, Jonathan Marchini (21497), Patricia A Cassano, Elliott, P., Susan R. Heckbert (110293), Wjst, M, Martin D. Tobin (110311), Wareham, Nicholas, North, KE, Spector, TD, David J Couper, Chen, Ting-hsu, Rotter, JI, Ramasamy, A., Nicholas J. Wareham (110277), Wain, Louise, Marjo-Riitta Jarvelin, Spector, Timothy D, Ma'en Obeidat, Psaty, Bruce M., Launer, Lenore, Lohman, Kurt, Adaikalavan Ramasamy (4841), Ma'en Obeidat (110232), Hartikainen, A.L., Peter Kraft, Gudnason, V., Dirkje S Postma, Strachan, D. P., Henry Völzke, Tobin, MD, Loehr, L. R., Morrison, Alanna C, Wain, LV, Thierry Rochat, Mcardle, Wendy, Smolonska, Joanna, Stricker, Bruno, Dirkje S. Postma (101740), Manning, AK, Barr, RG, Kraft, Phillip, Vonk, JM, Henry, A., Soler, Artigas, Bentley, A. R., Obeidat, Ma'en, Launer, L. J., Timothy D. Spector (110281), Strachan, David P, Brusselle, Guy, Christopher J. Hammond (110274), Liu, JZ, Loth, D. W., Vonk, Judith M., Wendy L. McArdle (110155), Bernd Meibohm, Loehr, LR, Hammond, Christopher J, Spector, T. D., Marchini, J., Cisca Wijmenga, Vonk, Judith M, Ting-hsu Chen, Ting-Hsu Chen (7634111), Barr, R Graham, Ruth J. F. Loos (110224), Hofman, Bert, Brusselle, G. G., North, Kari, Aschard, H., Kraft, P., Stephen B. Kritchevsky (110259), Bonnie R Joubert, David J. Couper (110257), O'Connor, G. T., Heinrich, J., Ting-hsu Chen (110239), Judith M Vonk, Ramasamy, Adaikalavan, Psaty, Bruce M, Sven Gläser (110276), Nicholas J. Wareham (7584569), Wain, L. V., Boezen, M, Aldrich, MC, Hancock, DB, Heckbert, SR, Hammond, C. J., H Marike Boezen, Christopher J. Hammond (7252211), North, Kari E., Zhai, G, Jing Hua Zhao (73808), Lumley, T, Aldrich, M., Smolonska, J., Vonk, J. M., Khaw, KT, Hartikainen, AL, Lenore J. Launer (7305602), Beate Koch (110151), Stricker, B. H. C., Heckbert, Susan, Kay-Tee Khaw, Williams, O. Dale, Uitterlinden, André, Hancock, Dana B., Ian P. Hall (110307), Kraft, P, Khaw, K-T, Kritchevsky, SB, Nora Franceschini, Jemma B. Wilk (110164), Wareham, Nicholas J, Georg Homuth (110202), Tobin, M. D., Curjuric, Ivan, Amy R. Bentley (110243), Joubert, B. R., Rochat, T, Gharib, Sina, Franceschini, N., Vilmundur Gudnason, Mirel, Daniel, Guangju Zhai, Janson, Christer,, Artigas, MS, Laura R. Loehr (110214), Rivadeneira, Fernando, Rich, SS, Melinda C. Aldrich (6688181), Boezen, HM, Albert V. Smith (103644), Manning, Alisa K, Morrison, Alanna C., Janson, C, Wijmenga, C, Jarvelin, M-R, Bentley, AR, Obeidat, M., David J. Couper (7634132), Mark Eijgelsheim, Kristin M. Burkart (110174), Bentley, Amy R., Jing Hua Zhao (7634084), Kristin M. Burkart (7634087), Loth, DW, Jonathan Marchini, London, SJ, Judith M. Vonk (71591), Kristin D Marciante, Spector, Timothy, Rivandeneiro, Fernando, Ani Manichaikul (110134), Rotter, J. I., Völzke, Henry, Aschard, Hugues, O'Connor, GT, Heinrich, J, Martin D. Tobin (7581161), Fornage, M., Barr, R. G., Bruce M. Psaty (103721), Gu, XJ, Zhai, Guangju, Jarvelin, M. R., Marciante, Kristin D, Ivan Curjuric (110179), Eiriksdottir, G., Susan R Heckbert, Sina A Gharib, Spector, Timothy D., Gläser, Sven, Homuyth, Georg, Medea Imboden (110145), Thomas Lumley, Hysi, Pirro G, Probst-Hensch, N. M., Gu, X., Harris, Tamara B., London, Stephanie J, Henry, Amanda, Joubert, BR, Peter Kraft (15118), Bruce M. Psaty (7634144), Bruno H.C. Stricker (7634156), Jerome I Rotter, Strachan, David, Wjst, M., Cathy C. Laurie (7634123), Meibohm, B., Launer, LJ (Lenore), Gudnason, Vilmundur, Hugues Aschard, Loehr, Laura R., Jarvis, D, Uitterlinden, André; id_orcid, Loth, Daan, Mirel, DB, Khaw, Kay-Tee, Postma, Dirkje S, Hall, Ian P, Rivadeneira, F., Deborah Jarvis (59834), Liu, Yongmei, Nicole M. Probst-Hensch (110284), Wilk, JB, Ivan Curjuric, Karl E. North (7634150), Curjuric, I, Liu, Jason Z., Kristin M Burkart, David P. Strachan (7634177), Burkart, Kristin M, Soler Artigas, María, Joanna Smolonska, Williams, O Dale, Kraft, Peter, Gläser, S, Pirro G. Hysi (7634090), Liu, J. Z., Eijgelsheim, M., Morrison, AC, Smith, A. V., Kay-Tee Khaw (110271), Wijmenga, Cisca, Albert Hofman, Elliott, P, Wendy L. McArdle (7634075), London, Stephanie J., Fornage, M, Gharib, Sina A., André G Uitterlinden, Voelzke, H, Loos, R., María Soler Artigas (110124), Hammond, CJ, Postma, Dirkje, Joubert, Bonnie, O'Connor, George T., Laurie, Cathy, Chen, T.H., McArdle, Wendy L, Kritchevsky, Stephen B, Glaeser, Sven, Loos, RJ, Alanna C. Morrison (7634126), Aldrich, Melinda C, Brusselle, Guy G, Cisca Wijmenga (32954), Joubert, Bonnie R., Imboden, M, Jemma B. Wilk (7634081), Jarvis, D., Rich, Stephen S, Ian P Hall, Christer Janson (83414), Sood, Akshay, McArdle, WL, Harris, T. B., Hammond, Christopher, Amanda Henry (110129), Kari E North, Couper, David J, Psaty, BM, Wenbo Tang, London, Stephanie, McArdle, W., Cathy C Laurie, Hartikainen, A-L, Louise V. Wain (110260), Wjst, Matthias, Hancock, Dana B, Bonnie R. Joubert (7634129), Janson, C., Koch, Beate, David P. Strachan (110302), Loos, Ruth, Wijmenga, C., Cassano, PA, Pirro G Hysi, Joubert, Bonnie R, Stricker, Bruno H C, Stephanie J London, Eijgelsheim, M, Georg Homuth, H. Marike Boezen (101746), Dupuis, J., Manning, Alisa, Tang, W., Kritchevsky, Stephen B., George T. O'Connor (7634147), Manichaikul, A., Laura R Loehr, Amy R. Bentley (7634120), Hofman, A, Postma, D., Stephen S. Rich (110262), Albert Hofman (107303), Wijmenga, Cisca; id_orcid, Matthias Wjst, Stricker, BH, Gharib, S. A., Wilk, Jemma, Burkart, Kristin M., Burkart, K. M., Beate Koch, Launer, LJ, O. Dale Williams (7634117), Cassano, Patricia A., Daniel B. Mirel (110265), Joachim Heinrich, Tang, WB, Janson, Christer, Postma, DS, Stephen S Rich, North, K. E., Thierry Rochat (110261), Paul Elliott (27295), Laura R. Loehr (7634096), Hall, Ian P., Nora Franceschini (91434), Tobin, Martin D., Aschard, H, Wain, Louise V, Liu, Y., Rotter, Jerome I., Wendy L McArdle, Lohman, K., Gudny Eiriksdottir, Williams, OD, Jason Z Liu, Anna-Liisa Hartikainen (110272), Wilk, Jemma B, María Soler Artigas, Yongmei Liu (104713), Cassano, Patricia, Fernando Rivadeneira (61551), Loos, Ruth JF, London, S.J. (Stephanie), Rivadeneira Ramirez, F. (Fernando), Morrison, A.C. (Alanna), Heinrich, J. (Joachim), Bentley, A.R. (Amy), Cassano, P.A. (Patricia), Hall, I.P. (Ian), Smolonska, J. (Joanna), Rich, S.S. (Stephen), Harris, T.B. (Tamara), Khaw, K-T. (Kay-Tee), Tobin, M.D. (Martin), O'Connor, G.T. (George), Janson, C. (Christer), Franceschini, N. (Nora), Laurie, C.C. (Cathy), Loehr, L.R. (Laura), Homuth, G. (Georg), Völzke, H. (Henry), Hancock, D.B. (Dana), Gläser, S. (Sven), Loos, R.J.F. (Ruth), Wareham, N.J. (Nick), Joubert, B.R. (Bonnie), Imboden, M. (Medea), Gudnason, V. (Vilmundur), Gharib, S.A. (Sina), Williams, O.D. (Dale), Uitterlinden, A.G. (André), Sood, A. (Akshay), Manichaikul, A. (Ani), Burkart, K.M. (Kristin), Wain, L.V. (Louise), Hammond, C.J. (Christopher), Brusselle, G.G. (Guy), McArdle, W.L. (Wendy), Psaty, B.M. (Bruce), Vonk, J.M. (Judith), Curjuric, I. (Ivan), Smith, A.V. (Davey), Marchini, J. (Jonathan), Aschard, H. (Hugues), Strachan, D.P. (David), Manning, A.K. (Alisa), Jarvis, D.L. (Deborah), Boezen, H.M. (Marike), Marciante, K. (Kristin), Dupuis, J. (Josée), Wjst, M. (Matthias), Zhai, G. (Guangju), Liu, Y. (YongMei), Rotter, J.I. (Jerome), Probst-Hensch, N.M. (Nicole M.), Rochat, T. (Thierry), Koch, B. (Beate), Heckbert, S.R. (Susan), North, K.E. (Kari), Wijmenga, C. (Cisca), Elliott, P. (Paul), Aldrich, M.C. (Melinda), Loth, D.W. (Daan), Stricker, B.H.Ch. (Bruno), Eiriksdottir, G. (Gudny), Jarvelin, M.-R. (Marjo-Riitta), Wilk, J.B. (Jemma), Tang, W. (Wenbo), Ramasamy, A. (Adaikalavan), Lohman, K. (Kurt), Mirel, D. (Daniel), Hysi, P.G. (Pirro), Spector, T.D. (Timothy), Henry, A. (Amanda), Hofman, A. (Albert), Kraft, P. (Peter), Zhao, J.H. (Jing Hua), Eijgelsheim, M. (Mark), Fornage, M. (Myriam), Liu, J. (Jason), Couper, D.J. (David), Gu, X. (Xiangjun), Lumley, T. (Thomas), Launer, L.J. (Lenore), Postma, D.S. (Dirkje), Barr, R.G. (Graham), Kritchevsky, S.B. (Stephen), Obeidat, M. (Ma'en), Meibohm, B. (Bernd), O'Connor, GT, Gläser, S., Völzke, H. +712 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan +16 more
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A Genome-Wide Association Study of Neuroticism in a Population-Based Sample [PDF]
, 2010 Neuroticism is a moderately heritable personality trait considered to be a risk factor for developing major depression, anxiety disorders and dementia. We performed a genome-wide association study in 2,235 participants drawn from a population-based study
Antoniades, A, Michael R. Johnson, Waeber, Gerard, Johnson, Michael R, Balding, David J, Calboli Federico C. F., Balding David J., Waterworth Dawn, Tozzi, Federica, Johnson Michael, R., Vincent Mooser, Tozzi Federica, Balding David, J., Calboli, Federico CF, Mooser, V, Federico C. F. Calboli, Federico C F Calboli, Tozzi, F, Galwey, Nicholas W, Vollenweider, Peter, Antoniades Athos, Waeber, G, Federica Tozzi, Muglia Pierandrea, Peter Vollenweider, Calboli, FCF, David J. Balding, Martin Preisig, Preisig, M, Pierandrea Muglia, Johnson Michael R., Dawn Waterworth, David J Balding, Galwey, NW, Antoniades, Athos, Muglia, P, Galwey Nicholas, W., Vollenweider, P, Michael R Johnson, Johnson, MR, Gerard Waeber, Mooser, Vincent, Waeber Gerard, Calboli Federico, C. F., Balding, DJ, Galwey Nicholas W., Nicholas W Galwey, Athos Antoniades, Vollenweider Peter, Preisig, Martin, Muglia, Pierandrea, Waterworth, Dawn, Mooser Vincent, Nicholas W. Galwey, Waterworth, D, Preisig Martin, Johnson, Michael R., Calboli, Federico C. F., Galwey, Nicholas W., Balding, David J. +59 more
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