Results 51 to 60 of about 42,684,660 (287)

Psoriasis: An Immunogenetic Perspective

Global Medical Genetics, 2022
Psoriasis is an erythematous-squamous dermatosis with a polygenic inheritance history. Both environmental and genetic factors play a role in the etiology of the disease.
Ayca Kocaaga, Mustafa Kocaaga
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Genome-Wide Association Studies of the PR Interval in African Americans [PDF]

, 2011
The PR interval on the electrocardiogram reflects atrial and atrioventricular nodal conduction time. The PR interval is heritable, provides important information about arrhythmia risk, and has been suggested to differ among human races.
Paltoo, Dina N., Smith, J Gustav, Smith, J.G., Heckbert, S.R., Zonderman, Alan B., Sotoodehnia, N., Mehra, R., Susan R. Heckbert, Ellinor, Patrick T, Palmer Cameron, Elsayed Z. Soliman, Benjamin, E.J., Newman, A.B., Müller, Martina, Kerr, K.F., Pfeufer, Arne, Newman, Anne B., Soliman, Elsayed Z, Magnani, JW, Candidate-gene Association Resource (CARe) Consortium, Ellinor Patrick T., Martina Müller, Kathleen F Kerr, Kerr, Kathleen F., Liu, Yongmei, Evans, Daniel S, Zonderman, Alan B, Palmer, C., Schnabel, Renate B, J Gustav Smith, Musani, Solomon K, Michele K Evans, Alonso Alvaro, Musani, Solomon K., Alonso, A, Newman, Anne B, Renate B Schnabel, Smith, JG, Smith, Gustav,, Schnabel Renate B., Magnani, Jared W., Emelia J Benjamin, null null, Ervin R Fox, Zonderman, AB, Jared W. Magnani, Paltoo, Dina N, Ellinor, Patrick T., Schnabel, R.B., Evans, M.K., Lund University., Kerr Kathleen F., Liu, Y, Cameron Palmer, Paltoo Dina N., Meng Yan A., Fox, Ervin R, Mehra Reena, Alonso, A., Patrick T. Ellinor, Anne B Newman, Redline Susan, Nalls, MA, Ellinor, PT, Schnabel, Renate B., Redline, Susan, Ellinor, P.T., Sotoodehnia, Nona, Nalls, Michael A., Arne Pfeufer, Smith J. Gustav, Newton-Cheh, Christopher, Solomon K Musani, Redline, S, Fox, ER, Renate B. Schnabel, Evans, Michele K., Mehra, R, Heckbert, SR, Meng, Yan A, Heckbert, Susan R, Christopher Newton-Cheh, Meng, YA, Evans, DS, Ervin R. Fox, Soliman Elsayed Z., Heckbert, Susan R., Michael A Nalls, Yan A. Meng, Fox, E.R., Susan Redline, Newton-Cheh Christopher, Fox, Ervin R., Evans, Michele K, Kathleen F. Kerr, Liu Yongmei, Alvaro Alonso, Nalls Michael A., Deo, R, Musani Solomon K., Newton-Cheh, C., Alan B. Zonderman, Soliman, EZ, Lubitz, S.A., Soliman, Elsayed Z., Dina N. Paltoo, Steven A Lubitz, Lubitz, SA, Alan B Zonderman, Evans, MK, Magnani, J.W., Patrick T Ellinor, Deo Rajat, Lubitz, Steven A, Nalls, Michael A, Pfeufer, A., Meng, Y.A., Evans Michele K., Benjamin, Emelia J., Benjamin Emelia J., Pfeufer Arne, Paltoo, D.N., Smith, J. Gustav, Sotoodehnia Nona, Elsayed Z Soliman, Soliman, E.Z., Jared W Magnani, Meng, Yan A., Redline, S., Newton-Cheh, C, Benjamin, Emelia J, Zonderman Alan B., Daniel S. Evans, Müller, M, Kerr, Kathleen F, Alonso, Alvaro, Rajat Deo, Kerr, KF, Schnabel, RB, Pfeufer, A, Müller, M., Paltoo, DN, Palmer, Cameron, Nona Sotoodehnia, Solomon K. Musani, Newman Anne B., Lubitz Steven A., Yongmei Liu, Zonderman, A.B., Nalls, M.A., Musani, S.K., Deo, Rajat, Musani, SK, Evans Daniel S., Deo, R., Dina N Paltoo, Newman, AB, Michele K. Evans, Mehra, Reena, Fox Ervin R., Yan A Meng, Evans, D.S., Evans, Daniel S., Benjamin, EJ, Susan R Heckbert, Emelia J. Benjamin, J. Gustav Smith, Reena Mehra, Palmer, C, Liu, Y., Magnani, Jared W, Anne B. Newman, Smith, Gustav, Daniel S Evans, Lubitz, Steven A., Steven A. Lubitz, Michael A. Nalls, Heckbert Susan R., Magnani Jared W., Müller Martina, Sotoodehnia, N, Smith, JG;Magnani, JW;Palmer, C;Meng, YA;Soliman, EZ;Musani, SK;Kerr, KF;Schnabel, RB;Lubitz, SA;Sotoodehnia, N;Redline, S;Pfeufer, A;Muller, M;Evans, DS;Nalls, MA;Liu, Y;Newman, AB;Zonderman, AB;Evans, MK;Deo, R;Ellinor, PT;Paltoo, DN;Newton-Cheh, C;Benjamin, EJ;Mehra, R;Alonso, A;Heckbert, SR;Fox, ER   +181 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A Genome-Wide Association Study Identifies Genomic Regions for Virulence in the Non-Model Organism Heterobasidion annosum ss [PDF]

, 2013
The dense single nucleotide polymorphisms (SNP) panels needed for genome wide association (GWA) studies have hitherto been expensive to establish and use on non-model organisms.
Olson, Åke, Brandström Durling, Mikael, Himmelstrand, Kajsa, Dalman, Kerstin, Stenlid, Jan, Lind, Mårten   +5 more
core   +3 more sources

Genome-Wide Association Study of Hepatitis in Korean Populations [PDF]

Genomics & Informatics, 2014
Hepatitis is a common and serious disease for the Korean population. It is caused by a virus, the A and B types of which are plentiful in Koreans. In this study, we tried to find genetic factors for hepatitis through genome-wide association studies.
Youngbok Hong, Sejong Oh
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Genome-wide association study of behavioural and psychiatric features in human prion disease. [PDF]

, 2015
Prion diseases are rare neurodegenerative conditions causing highly variable clinical syndromes, which often include prominent neuropsychiatric symptoms.
Carswell, C, MacKay, A, Thompson, AG, Porter, MC, Rudge, P, Collinge, J, Lowe, J, Mead, S, Uphill, J, Lukic, A   +9 more
core  

A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain [PDF]

, 2014
Background: Neuropathic pain, caused by a lesion or a disease affecting the somatosensory system, is one of the most common complications in diabetic patients.
Palmer, C. N. A.; id_orcid, H.M. Colhoun, C.N.A. Palmer, Colhoun, H. M., L.A. Donnelly, Liu, Y., Zhou, K., Palmer, C. N A, van Zuydam, N. R., Smith, B. H.; id_orcid, H.A. Deshmukh, N.R. van Zuydam, K. Zhou, A.D. Morris, Donnelly, L. A., Deshmukh, H. A., Morris, A. D., Meng, W., Smith, B. H., Y. Liu, B.H. Smith, W. Meng   +21 more
core   +1 more source

Genome- and epigenome-wide association studies identify susceptibility of CpG sites and regions for metabolic syndrome in a Korean population

Clinical Epigenetics
Background While multiple studies have investigated the relationship between metabolic syndrome (MetS) and its related traits (fasting glucose, triglyceride, HDL cholesterol, blood pressure, waist circumference) and DNA methylation, our understanding of ...
Ho-Sun Lee, Boram Kim, Taesung Park
doaj   +1 more source