Results 1 to 10 of about 732,673 (145)

Advances in genome-wide DNA methylation analysis [PDF]

open access: yesBioTechniques, 2010
The covalent DNA modification of cytosine at position 5 (5-methylcytosine; 5mC) has emerged as an important epigenetic mark most commonly present in the context of CpG dinucleotides in mammalian cells.
Romi Gupta   +2 more
doaj   +3 more sources

Power analysis for genome-wide association studies [PDF]

open access: yesBMC Genetics, 2007
Background Genome-wide association studies are a promising new tool for deciphering the genetics of complex diseases. To choose the proper sample size and genotyping platform for such studies, power calculations that take into account genetic model, tag ...
Klein Robert J
doaj   +3 more sources

Genome wide Association Analysis

open access: yesMolecular Plant Breeding, 2021
Plant β-galactosidases (BGALs) are the important glycosidase that hydrolyses the non-reductive terminaβ-D-galactosidase residues from glycochains, glycolipids and glycoproteins.In order to reveal the regulation mechanism of β-galactosidases in cotton development, the whole genome analysis of BGAL gene family were carried out in this study, which laid a
Xiaocong Cao   +7 more
openaire   +2 more sources

Genome-wide analysis of insomnia disorder [PDF]

open access: yesMolecular Psychiatry, 2018
Insomnia is a worldwide problem with substantial deleterious health effects. Twin studies have shown a heritable basis for various sleep-related traits, including insomnia, but robust genetic risk variants have just recently begun to be identified. We conducted genome-wide association studies (GWAS) of soldiers in the Army Study To Assess Risk and ...
Murray B. Stein   +13 more
openaire   +4 more sources

Robust Gene-Gene Interaction Analysis in Genome Wide Association Studies. [PDF]

open access: yesPLoS ONE, 2015
Genome-wide association studies (GWAS) have successfully discovered hundreds of associations between genetic variants and complex traits. Most GWAS have focused on the identification of single variants.
Yongkang Kim, Taesung Park
doaj   +1 more source

Genome wide association analysis of cuticle deposition in laying hens

open access: yesPoultry Science, 2023
: The cuticle is an invisible barrier that protects the internal egg contents from microorganisms entering through gas exchange pores. Eggs which have a good cuticle are least likely to be penetrated by microorganisms and improved cuticle cover should ...
Zhang Wang   +8 more
doaj   +1 more source

A genome‐wide analysis of the USDA Soybean Isoline Collection

open access: yesThe Plant Genome, 2023
The USDA Soybean Isoline Collection has been an invaluable resource for the soybean genetics and breeding community. This collection, established in 1972, consists of 611 near‐isogenic lines (NILs) carrying one or multiple genes conferring traits that ...
Erin Gilbert   +4 more
doaj   +1 more source

An Analysis Pipeline for Genome-wide Association Studies

open access: yesCancer Informatics, 2008
We developed an efficient pipeline to analyze genome-wide association study single nucleotide polymorphism scan results. Perl scripts were used to convert genotypes called using the BRLMM algorithm into a modified PB format.
Stefan Stefanov   +2 more
doaj   +2 more sources

Genome wide analysis of Arabidopsis core promoters

open access: yesBMC Genomics, 2005
Background Core promoters are the gene regulatory regions most proximal to the transcription start site (TSS), central to the formation of pre-initiation complexes and for combinatorial gene regulation.
Molina Carlos, Grotewold Erich
doaj   +1 more source

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