Results 131 to 140 of about 754,015 (260)

Integrative gene duplication and genome-wide analysis characterize Peroxin11 gene family in wheat. [PDF]

BMC Genomics
Ebeed HT.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Genome-Wide Analysis Identifies <i>ScTCP6</i> as a Stress Responsive Gene in Rye. [PDF]

Curr Issues Mol Biol
Ren Y, Ma R, Wang Z, Li L, Xie M, Jiang T, Zhang J, Lian Q.   +7 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Genome-wide analysis of inbreeding patterns and candidate genes for adaptation in indigenous chickens of Botswana. [PDF]

Poult Sci
Machete JB, Chalebgwa AB, Monau PI, Kgwatalala PM, Moreki J, Nsoso SJ.   +5 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Genome-Wide Analysis of AGPase Identifies <i>CsAGP4</i> as a Regulator of Watermelon Mosaic Virus Resistance in Cucumber. [PDF]

Int J Mol Sci
Sun X, Guan J, Miao H, Liu X, Gu X, Dong S, Zhang S.   +6 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Genome-wide Analysis of Mycoplasma hominis for the Identification of Putative Therapeutic Targets

Drug Target Insights, 2014
Md. Masud Parvege, Monzilur Rahman, Mohammad Shahnoor Hossain   +2 more
doaj  

Genome-wide analysis of the <i>GID</i> gene family in soybean and analysis of expression under gibberellin treatment. [PDF]

Front Plant Sci
Yao Z, Lv C, Zhang Y, Yang J, Huang S, Wang J, Hao Z, Zhao C, Sun H, Sun W, Liu L, Wang H, Zhang Q, Wang P.   +13 more
europepmc   +1 more source