Results 81 to 90 of about 25,155,128 (260)
Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution [PDF]
, 2009 To identify genetic loci influencing central obesity and fat distribution, we performed a meta-analysis of 16 genome-wide association studies (GWAS, N = 38,580) informative for adult waist circumference (WC) and waist–hip ratio (WHR). We selected 26 SNPs
Boehnke, M., Silander, K, Munroe, P., Lyon, H.N. (Helen), Lamina, C., Holle, R. (Rolf), Doering, A., Mohlke Karen L., Sanna, Serena, McCarthy, Mark I, Karpe, F, Qi, L., Amin, N. (Najaf), Mangino, M., Ruokonen, A., Bandinelli, S, Franks, P.W., Toshiko Tanaka, Kuusisto, J, Randall, Joshua C, Bonnycastle, LL, Sanna, S., Renström, F. (Frida), Hu, F. B, Anna Nordström, Tiinamaija Tuomi, Silander, K., Forouhi Nita G., Day, I.N.M., Qi Lu, Scott Laura J., Mangino Massimo, Hirschhorn, Joel, Heid Iris M., Qi, Lu, Palmer, CN, Uitterlinden, André G, Groop, L., Forouhi, Nita G., Davey Smith George, Hunter David J., Fischer, G., Barroso, Inês, Cuilin Zhang, Loos, Ruth J F, Hugh Watkins, Lindgren, C. M, Zillikens, M. Carola, Willer, C. J, Davey Smith, George, Stefansson, K, Chambers, John C, Qi, L. (Lu), Randall, J.C., Jacobs, Leonie C, Frayling, Timothy M., Michael R. Erdos, Almgren, P., Waeber Gerard, Caulfield Mark J., Timpson, Nicholas J, Hofman, A., Lu Qi, Vollenweider Peter, Palmer, C.N.A. (Colin), Waterworth, D. (Dawn), Valgerdur Steinthorsdottir, Jarvelin, Marjo-Riitta, Davey Smith, G., Cecilia M Lindgren, McArdle, W. L, Kong, A., Nordström, P, Herrera, B.M. (Blanca), Wichmann, H-E, Manjinder S Sandhu, Qi, L, Markku Laakso, Estrada, K, Smith, GD, Rivadeneira, F, Bergman, R.N., Almgren, Peter, Gonçalo R Abecasis, Uitterlinden, A. G, Strachan, David P., Salomaa, Veikko, Timothy D. Spector, Bergman, Richard N., Collins, Francis S, Gieger Christian, Laakso, M, Payne Felicity, Hofman Albert, Lori L. Bonnycastle, Cherkas, Lynn, Blanca M. Herrera, Hattersley, A. T, Peter Nordström, Fischer, G, McCarthy, MI, Thorleifsson,Gudmar, Schlessinger, D. (David), Zhang, W., Andrew D. Morris, Doney, Alex S F, Morris, Andrew, Thomas Illig, Kong Augustine, Crawford, G., Ruokonen, A. (Aimo), Fischer, G. (Guido), Waterworth, Dawn M., John C. Chambers, Renstroem, Frida, Day, I.N.M. (Ian), Stringham, Heather M., Scuteri, Angelo, Morris, AD, Yurii S. Aulchenko, Doney, AS, Morris, AP, Guiducci Candace, Mark J Caulfield, Caulfield, M.J., Kooner, J.S., Hadley, D., Herrera, Blanca M., Lyon, HN, Fernando Rivadeneira, Holloway, J.W., Jaakko Tuomilehto, Debbie A Lawlor, Gieger, C. (Christian), George Davey Smith, Lachlan Coin, Lyon, Helen N, Wareham, N.J., Weedon, Michael N., Nicholas J. Timpson, Mangino, M, Kooner, Jaspal S, Zillikens, M. C, Sandhu, M.S. (Manjinder), Morris, A. D, Almgren, P, Yuan, X., Morris, A. P, Nicholas J. Wareham, Karen Jameson, Lim, N., Chanock, S.J., Loos, Ruth J. F., Stringham, H.M. (Heather), Doney, Alex SF, Illig, T., Zhang, WH, Swift, A.J. (Amy), Hunter, DJ, Holloway, JW, McCarthy, Mark, Colin N A Palmer, Loos, RJF, Havulinna, A.S. (Aki), Groves, C.J., Collins, F.S., Jackson, A.U., Andrew P Morris, Estrada, K., Swift, A. J, Drong Alexander, Ian N M Day, Iris M Heid, Sanna Serena, Morris, A.P. (Andrew), Waterworth, DM, Ruokonen, Aimo, Ferrucci Luigi, Yuan Xin, Aulchenko, Y.S., Frayling, T.M. (Timothy), Joel N. Hirschhorn, Iris M. Heid, Kooner, J.S. (Jaspal), Cornelia M. van Duijn, Uitterlinden, André G., Almgren, P. (Peter), Wellcome Trust Case Control Consortium, Consortium, GIANT, Swift Amy J., Hirschhorn, J.N. (Joel), Ruokonen Aimo, Jacobs Leonie C., Bergman, RN, Nordström, A, Waterworth, Dawn M, Herrera, BM, Jackson Anne U., Thorsteinsdottir, U, M Carola Zillikens, Mark I. McCarthy for the GIANT consortium, Ruth J F Loos, Jarvelin, MR, Lamina Claudia, Jing Hua Zhao, Salomaa, V. (Veikko), van Duijn, Cornelia M., McArdle, W.L. (Wendy), Groves Christopher J., Hadley, D. (David), Laura J Scott, Thorsteinsdottir, U. (Unnur), Luan, J., Groop, L. (Leif), Hugh Watkins for the PROCARDIS consortia, Debbie A. Lawlor, Walters, G.B., Grundy, S, Jackson, Anne U, Steinthorsdottir, V. (Valgerdur), Walters, G. Bragi, Heid, I. M, Crawford Gabriel, Aki S Havulinna, Collins, FS, Silander Kaisa, Ruokonen, A, Randall, J.C. (Joshua), Zhao, JH, Franks, P.W. (Paul), Kuusisto, J. (Johanna), Laakso, M. (Markku), Palmer, CNA, Amin Najaf, Oostra, Ben A, Doney, A.S., Schlessinger, David, Illig, Thomas, Hirschhorn, Joel N, David J. Hunter, Salomaa Veikko, Day Ian N. M., Hu, Frank, Tuomi, T., Vollenweider, P, Laakso, Markku, Ebrahim, S. (Shanil), Oostra Ben A., Jaspal S. Kooner, Yuan, Xin, Lathrop, G Mark, Thomas Meitinger, Lamina, Claudia, Hadley, David, Barroso, I.E. (Inês), Soranzo Nicole, Elliott, P., Dawn M. Waterworth, Andrew P. Morris, Laitinen, J., Drong, A, Franks, PW, Nordström Anna, Claudia Lamina, Helen N. Lyon, Luan, JA, Suzannah J Bumpstead, McCarthy, M.I. (Mark), Aimo Ruokonen, Tanaka, T, Marjo-Riitta Jarvelin, Spector, Timothy D, Aulchenko, Y.S. (Yurii), Francis S. Collins, Lakatta, E., Richard N Bergman, Luan, Jian'an, Panos Deloukas, Dawn M Waterworth, Stringham, Heather M, Morris, Andrew D., Ebrahim, S, Najaf Amin, Allison, David B., Cons, WTCC, Doney, ASF, Walters, G Bragi, Caulfield, Mark J., Procardis Consortia, Tuomilehto, J., Swift, Amy J, Chanock, S. J, Ebrahim, Shah, Erdos, M. R, Peter Chines, Cherkas, L., Sandhu, Manjinder S., Deloukas, P, Guiducci, Candace, Cooper Cyrus, Paul W. Franks, Strachan David P., Hunter, D.J. (David), Crawford, G. (Gabe), Lathrop, G. Mark, Song, K. (Kijoung), Serena Sanna, Holle, Rolf, Doering, A, Estrada Karol, Heid, I.M. (Iris), Michael R Erdos, Salomaa, V., Stringham Heather M., Bumpstead Suzannah J., Uda, M, Ian N. M. Day, Mohlke, K.L., Hunter, D.J., Guiducci, C, Stringham, H. M, Bennett, A.J., Renström Frida, Scheet, P., Narisu, Narisu, Song, K, Vollenweider, P., Waeber, G. (Gérard), Collins, F.S. (Francis), Bennett, Amanda J, Xin Yuan, Leena Peltonen, David J Hunter, Scuteri Angelo, Meitinger, T., Day, Ian N. M., Grallert, H., Jacqueline C. M. Witteman, Kari Stefansson, Mario A. Morken, Steinthorsdottir, V., Rivadeneira Fernando, Frida Renström, Hu, Frank B., Gonçalo R. Abecasis, Mohlke, K.L. (Karen), Karol Estrada, Lindgren, Cecilia M, Inga Prokopenko, David P. Strachan, Joshua C Randall, Wareham, Nicholas J, Lawlor Debbie A., Mario A Morken, Döring, A., Smith, G.D., Chines, P, Barroso, I., Helen N Lyon, Timothy M Frayling, G Mark Lathrop, Chanock, Stephen J., Doering, Angela, Cristen J. Willer, Palmer, Colin N A, Day, I. N. M, Heid, Iris M, Lathrop, G.M. (Mark), Hattersley, A.T., McCarthy, M. I, Barroso, IS, Jameson, K. (Karen), Guiducci, C. (Candace), Samani, N.J., Havulinna, A. S, Morris Andrew D., Jarvelin, M.-R. (Marjo-Riitta), Coin, L. (Lachlan), Willer, C.J. (Cristen), Scott, Laura J, Joshua C. Randall, Soranzo, N., Peltonen, Leena, Alexander Drong, John F. Peden, Waeber, G., Lawlor, D.A., Hu, FB, Holloway John W., Frayling, T. M, Blanca M Herrera, Boehnke, Michael, Walters, G.B. (Bragi), Havulinna Aki S., Wichmann, HE, Jameson Karen, Lindgren, C.M. (Cecilia), Heather M. Stringham, Franks Paul W., Steinthorsdottir, Valgerdur, Watkins, H. (Hugh), Silander, Kaisa, Kooner, J. S, Jousilahti, P, Pekka Jousilahti, Gerard Waeber, Spector, Timothy D., McArdle Wendy L., Tuomi, T. (Tiinamaija), Tanaka, T. (Toshiko), Tuomi Tiinamaija, Karpe, F., Candace Guiducci, Jing, H.Z., Estrada Gil, K. (Karol), Frayling, Timothy M, Mooser Vincent, Lakatta Edward, Lyon, H. N, Leonie C Jacobs, Erdos, M.R. (Michael), Abecasis, Gonçalo R, David Schlessinger, Illig, T, Bandinelli, S. (Stefania), Barroso, I.S., Walters G. Bragi, Munroe Patricia, Wendy L. McArdle, Aulchenko, Yurii S., Nilesh J. Samani, Peden, John F., Cristen J Willer, Weedon Michael N., Veikko Salomaa, Prokopenko, I, Payne, Felicity, Collins Francis S., Chambers, J.C., Holloway, J.W. (John), Day, I.N., Holle, R., Samani Nilesh J., Hugh Watkins, D.M., Jackson, A.U. (Anne), Amin, N, Stefansson, Kari, Samani, Nilesh J, Peltonen, L. (Leena Johanna), Hattersley, Andrew T, Spector, T.D. (Timothy), Hamsten Anders, Kaisa Silander, Doering, A. (Angela), Collins, F. S, McArdle, W.L., Hirschhorn, J.N., Vollenweider, Peter, Abecasis, G. R, Soranzo, Nicole, Michael N Weedon, Hofman, A. (Albert), Palmer, C.N., Hattersley, AT, Albert Hofman, Elliott, P, Amanda J Bennett, Song Kijoung, Song, K.J., Uitterlinden André G., Randall, Joshua C., Drong, A. (Alexander), Scott, L.J. (Laura), Lindgren Cecilia M., Elizabeth K Speliotes, Bennett Amanda J., Willer, Cristen J, Cooper, C. (Charles), Gieger, Christian, Payne, F. (Felicity), Hu Frank B., Lim Noha, Caulfield, MJ, Van Duijn, C. M, Waterworth, D. M, Bonnycastle, L.L., Nordstrom, P., Gabriel Crawford, Doney, A. S. F, Grundy Scott, Dominiczak, A., Loos, RJ, Kooner, Jaspal S., Kooner, JS, Lamina, C, Forouhi, N. G, Doney, A.S.F. (Alex), Kuusisto, Johanna, Morken, M.A., Chanock, S.J. (Stephen), Thorleifsson, Gudmar, Zhang Weihua, Munroe, P, Witteman, J. C. M, Amin, N., Weedon, MN, Timpson Nicholas J., Oostra, B.A., Luan, J, Watkins, Hugh, Lakatta, Edward, Christian Gieger, Zhao Jing Hua, Morken, M.A. (Mario), Bandinelli Stefania, Bergman, Richard N, Aki S. Havulinna, Nordström Peter, Jacobs, L.C., Morken, Mario A, Lathrop, G.M., Scott, Laura J., Anna Dominiczak, Song, Kijoung, Michael Boehnke, Franks, P. W, Spector, T.D., Lindgren, CM, Loos, R.J.F., Groves, C.J. (Christopher), Zillikens M. Carola, Holle Rolf, Scott, LJ, Bumpstead, S.J., Forouhi, NG, Waeber, G, Aulchenko, Yurii S, Steinthorsdottir Valgerdur, Doney, Alex S. F.; id_orcid, Kuusisto Johanna, Loos, R.J., Andrew T. Hattersley, Renström, F, Grallert, H, Wichmann, H. -E, Lamina, C. (Claudia), Sanna, S. (Serena), Morris, A.P., Caulfield, M. J, Karen L. Mohlke, Jameson, K., Sandhu, M.S., Forouhi, N.G. (Nita), Anne U. Jackson, Zillikens, MC, Meitinger, T. (Thomas), Leif Groop, Dominiczak, A. (Anna), Loos, R. J. F, Deloukas, P. (Panagiotis), Erdos, Michael R, Jacobs, L.C. (Leonie), Timpson, N.J., Tuomilehto Jaakko, Barroso, Ine S., Bumpstead, Suzannah J, Tuomilehto, Jaakko, Jackson, A. U, Palmer, Colin N. A.; id_orcid, Ebrahim Shah, Zhang Cuilin, Coin, Lachlan, Uda, M., Samani, NJ, Abecasis, Gonçalo R., Chines Peter, Witteman, JC, Rivadeneira Ramirez, F. (Fernando), Franks, Paul W,, Franks, Paul W., Schlessinger David, Laakso Markku, Amin, Najaf, Kijoung Song, Morris Andrew P., Caulfield, M. (Mark), Wareham, N. J, Sandhu, MS, Boehnke, M, Groop, L, Ruth J. F. Loos, Sanna, S, H.-Erich Wichmann, Isomaa, B., Jackson, Anne U., Wichmann, H.-E., Elliott, Paul, Joel N Hirschhorn, Renstrom, F., Illig Thomas, Chambers John C., Peltonen, L, Palmer, Colin N. A., Hu, F.B., Yuan, X. (Xin), Peden, J. (John), Peter Vollenweider, Cherkas, L. (Lynn), Ben A. Oostra, Groop Leif, Swift, A.J., Manuela Uda, Groves, Christopher J, Thorleifsson, G. (Gudmar), Isomaa, B. (Bo), Palmer, Colin NA, Heather M Stringham, Ebrahim, S., Wichmann, H.E., Heid, I.M., Kong, Augustine, Lawlor, D.A. (Debbie), Zhang, W, Mooser, Vincent, Uitterlinden, AG, Illig, T. (Thomas), David P Strachan, Zillikens, M.C. (Carola), Bandinelli, S., Speliotes, E.K., Chambers, J.C. (John), Manjinder S. Sandhu, Gieger, C, Nordström, Peter,, Scott, L. J, Chanock, Stephen J, Amanda J. Bennett, Zhang, C, McCarthy for the GIANT consortium, Mark I., Wichmann, H-Erich, Unnur Thorsteinsdottir, Watkins, H., Erdos, Michael R., Cornelia M van Duijn, Schlessinger, D., Timothy D Spector, Isomaa, B, Narisu, N., Silander, K. (Kaisa), Mark J. Caulfield, Chris Wallace, van Duijn, CM, Scheet, P. (Paul), Zhang, W.H., Havulinna, Aki S., Jarvelin, M.R., Ferrucci, L. (Luigi), Bumpstead, Suzannah J., Hirschhorn, J. N, Havulinna, A.S., Scott Grundy, Wallace, Chris, Fredrik Karpe, Kooner Jaspal S., Munroe, P. (Patricia), ?, ?, Salomaa, V, Zhao, Jing Hua, Steinthorsdottir, V, Zwart, J-A. (John-Anker), Witteman, Jacqueline C M, Consortia, HWPROCARDIS, Michael N. Weedon, Zillikens, M Carola, Lori L Bonnycastle, Jaspal S Kooner, Jarvelin Marjo-Riitta, Soranzo, N. (Nicole), Grallert Harald, Renstroem, F, Hirschhorn Joel N., Uda, Manuela, Palmer, C. N. A, Bandinelli, Stefania, Isomaa, Bo, Prokopenko, Inga, Zillikens, M.C., Francis S Collins, Narisu Narisu, Lathrop, G. M, Amy J Swift, Groves, Christopher J., Lawlor, Debbie A., Jacqueline C M Witteman, Loos, R.J.F. (Ruth), Wareham, N.J. (Nick), Frayling Timothy M., Chines, P., Scuteri, A., Deloukas Panos, Hunter, David J, Timpson, N. J, Abecasis, G.R., Nicholas J Timpson, Jousilahti Pekka, Morris, Andrew P, Morris, Andrew D, Herrera, B.M., Renström, Frida, Nicholas J Wareham, Tuomilehto, J. (Jaakko), Coin, L., Stringham, H.M., Nordstrom, A., Bennett, A.J. (Amanda), Augustine Kong, Vincent Mooser, Laakso, M., Narisu, N. (Narisu), Rolf Holle, Ferrucci, L, Kuusisto, J., van Duijn, C.M., Laitinen, J, Almgren Peter, Colin N. A. Palmer, Nordström, Anna, Karpe Fredrik, Uitterlinden, A.G. (André), Forouhi, Nita G, McArdle, Wendy L., Anders Hamsten, G Bragi Walters, Luigi Ferrucci, M. Carola Zillikens, Cherkas, L, Edward Lakatta, Hunter, D. J, Lim, N. (Noha), Paul Elliott, Nordstroem, P, Morris, A.D., H-Erich Wichmann, Willer, C.J., Deloukas, P., Yuan, X, Mooser, V. (Vincent), Lyon Helen N., Spector Timothy D., Suzannah J. Bumpstead, Grundy, S.M. (Scott), Uitterlinden, André G.; id_orcid, Doney, Alex S.F., Franks, Paul, Wareham, NJ, Peden, J. F, Frayling, TM, Chambers, John C., Nita G Forouhi, McCarthy, M.I., Holloway, John W., Waeber, Gerard, John F Peden, Morris, Andrew P., Jameson, Karen, Grallert, H. (Harald), The Wellcome Trust Case Control Consortium, Amy J. Swift, Walters, G. B, Collins, Francis S., Samani, N.J. (Nilesh), Boehnke Michael, Willer Cristen J., Wallace, C., Deloukas, Panos, Samani, N. J, Dominiczak Anna, Strachan, D. P, Zhang, C.L., Prokopenko Inga, Witteman Jacqueline C. M., Chanock, SJ, Wareham, Nicholas J., Laura J. Scott, Grundy, Scott, Laitinen, Jaana, Watkins for the PROCARDIS consortia, Hugh, Elizabeth K. Speliotes, Stephen J. Chanock, Wichmann H.-Erich, Boehnke, M. (Michael), Tikka-Kleemola, P. (Päivi), Abecasis, GR, Oostra, B.A. (Ben), Walters, GB, Oostra, BA, Speliotes, EK, Karpe, Fredrik, Timpson, Nicholas J., Smith, A.V. (Davey), Jing, H. Z, Zhao, J.H., Hofman, Albert, Tuomilehto, J, Isomaa Bo, Mark I McCarthy, André G. Uitterlinden, Scheet Paul, Bumpstead, SJ, Meitinger, Thomas, Crawford, G, Morken, MA, Holle, R, Hamsten, A, Strachan, D.P. (David), Weedon, M.N., Franks, Paul W, Christopher J. Groves, Crawford, Gabriel, van Duijn Cornelia M., Day, Ian N M, Sandhu, M. S, Strachan, DP, G. Mark Lathrop, Coin Lachlan, Lakatta, E. (Edward), Bonnycastle Lori L., Stefania Bandinelli, Spector, TD, Jacobs, Leonie C., Bo Isomaa, Witteman, J.C., Frank B Hu, Anne U Jackson, Mohlke, Karen L, Wichmann, H. -Erich, Payne, F., Elliott Paul, Paul Scheet, Uda Manuela, Hu, F.B. (Frank), Waterworth Dawn M., Ferrucci, L., Bonnycastle, L. L, Wichmann, H.E. (Erich), Stefansson Kari, Timothy M. Frayling, Mohlke, Karen L., Speliotes, E.K. (Elizabeth), Heid, Iris M., Tanaka, T., Lindgren, Cecilia M., Hattersley, Andrew T., Jackson, AU, Jousilahti, P., Peden, JF, Uda, M. (Manuela), Witteman, Jacqueline C. M., Herrera, Blanca M, Wallace, C. (Chris), Peltonen, L., Nordström, Peter, Strachan, David P, Groves, C. J, Hunter, David, Abecasis, G.R. (Gonçalo), Tanaka Toshiko, Speliotes, Elizabeth K, Hu, Frank B, Samani, Nilesh J., Smith, G. D, Sandhu, Manjinder S, Chines, P.S. (Peter), Prokopenko, I. (Inga), Watkins, H, Herrera, B. M, Wallace Chris, Harald Grallert, McCarthy For The Giant Consortium, MI, Jousilahti, P. (Pekka), Palmer, C.N.A., Ferrucci, Luigi, Soranzo, N, Andrew T Hattersley, Bergman, R. N, Paul W Franks, Oostra, B. A, Speliotes, Elizabeth K., Cooper, C., Stephen J Chanock, Nita G. Forouhi, Aulchenko Yurii S., Holloway, J. W, Heid, IM, Jarvelin, Marjo Riitta, Wallace, C, Havulinna, AS, Day, IN, Wichmann, H.-Erich, Meitinger Thomas, Hamsten, A., Sandhu Manjinder S., Bumpstead, S. (Suzannah), Gieger, C., Nordström, A. (Anna), Hattersley Andrew T., Doering Angela, Zhang, CL, Morken Mario A., Shah Ebrahim, Rivadeneira, Fernando, Elliott, P. (Paul), John W Holloway, Lathrop, GM, Gudmar Thorleifsson, John W. Holloway, Herrera Blanca M., Willer, CJ, Coin, L, Grallert, Harald, Cyrus Cooper, Richard N. Bergman, Noha Lim, Jarvelin, M-R, Weihua Zhang, Karen L Mohlke, Laitinen Jaana, Speliotes Elizabeth K., Fischer Guido, Zhang, C., Lawlor, DA, Havulinna, Aki S, Leonie C. Jacobs, Jarvelin, M. -R, Bumpstead, S. J, Chambers, JC, Waterworth, D.M., Thorsteinsdottir Unnur, Peden John F., Guiducci, C., Scheet, Paul, Mangino, Massimo, McCarthy for the GIANT consortium Mark I., Bergman, R.N. (Richard), Hadley, D, Lawlor, D. A, Lim, Noha, Thorsteinsdottir, Unnur, Christopher J Groves, Willer, Cristen J., Renström, Frida,, Lynn Cherkas, Hamsten, A. (Anders), Cherkas Lynn, Davey Smith, G, Palmer Colin N. A., Stefansson, K., Dominiczak, A, Chines, Peter, Lyon, Helen N., Forouhi, N.G., Karpe, F. (Fredrik), Payne, F, Nordström, Anna,, Munroe, Patricia, Randall, JC, Scheet, P, Kong, A, Doney, Alex S. F., Johanna Kuusisto, Bergman Richard N., McCarthy, Mark I., Massimo Mangino, Wellcome Trust Case Control Consor, Peden, J.F., Hunter, David J., Fischer, Guido, Thorleifsson, G, Timpson, NJ, Doney Alex S. F., Jousilahti, Pekka, Thorleifsson Gudmar, Frank B. Hu, Strachan, D.P., Holloway, John W, Peter Almgren, Scuteri, A, Peden, John F, Hadley David, Alex S. F. Doney, Yurii S Aulchenko, Ben A Oostra, Rivadeneira, F., Jameson, K, Kong, A. (Augustine), Chanock Stephen J., Angelo Scuteri, Mooser, V, Song, K., Hattersley, A.T. (Andrew) +999 more
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini +8 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
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Genome-wide Analysis of Seasonal Reproduction in Birds
The Journal of Poultry Science, 2009 Many seasonal breeding animals can estimate the day length (photoperiod) and prepare for breeding in the optimal season. The Japanese quail (Coturnix japonica) is an excellent model for studying photoperiodism because of its rapid and dramatic response ...
Nobuhiro Nakao
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan +4 more
wiley +1 more source
Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function [PDF]
, 2014 Background: Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung function.
Wenbo Tang (110161), Joyanna G. Hansen (591398), Heinrich, J (Joachim), Thomas Lumley (57337), London, S.J. (Stephanie), Alan James (528475), Sood, A, R Graham Barr, Matthew Kowgier (120923), Brusselle, Guy G., Loth, Daan W, Akshay Sood (71826), O'Connor, George T, Susan R. Heckbert, Liu, YM, Rivadeneira Ramirez, F. (Fernando), Hodge, E., Harris, Tamara B, Michael Allerhand, Loth Daan W., Morrison, A.C. (Alanna), Fornage, Myriam, Morris Andrew P., Ingo Ruczinski, Stephanie J. London (62450), Josée Dupuis (28859), James, Alan, Völzke Henry, Ruczinski, I., London Stephanie J., Voorman, A, Patricia A. Cassano (110298), Joachim Heinrich (60421), Guy G Brusselle, Gu, Xiangjun, Mathias, Rasika A, John M Starr, Smith, AV, Couper, DJ, Lenore J. Launer (110269), Arend Voorman, Myriam Fornage (45591), Sina A. Gharib, Smith, Lewis J, Gao, W, Wei Gao, Liu, Y, Morrison Alanna C., Kari E. North, Musk, B, Heinrich, J. (Joachim), Musk Bill, Uitterlinden, André G, Hansel, C.R.W. (Christian), Dupuis, Jos�e, John M. Starr, Heinrich, Joachim, Foy, Millennia, Lind, Lars, Cassano, P.A. (Patricia), Probst-Hensch, Nicole M, Palmer, Lyle J., O Dale Williams, Joyanna G. Hansen, Allerhand, Michael, Martin D. Tobin, Deary, Ian J, Hall, I.P. (Ian), Uitterlinden, AG, Heckbert, Susan R, David P Strachan, Tamara B Harris, Harris, T.B. (Tamara), Smith, Albert V, Launer, Lenore J, Stricker, Bruno H, Starr John M., Heckbert, Susan R., Holger Schulz (13022), Tamara B. Harris, James, A. (Alan), Tobin, M.D. (Martin), Michael Allerhand (591399), Martin T. Wells, Kari E. North (68131), Aldrich, Melinda C., Couper, David J., North, Kari E, Louise V Wain, Starr, John M., Rivadeneira, F, Jerome I. Rotter, Barnes, Kathleen C, O'Connor, G.T. (George), Smith, Lewis J., Kowgier, M., Karrasch Stefan, Strachan, David P., Henry Völzke (64286), Williams O. Dale, Ingelsson, Erik, Hodge Emily, Soler Artigas, Mar�a, Bernd Meibohm (110267), Gu Xiangjun, Ingelsson Erik, Cecilia Lindgren (258113), Daan W Loth, Hofman Albert, Gl�ser, Sven, Starr, J.M. (John), Deary, I.J. (Ian), Ashish Kumar, et al., Kurt Lohman, Bonnie R. Joubert, Alanna C Morrison, Melinda C. Aldrich (110234), Meibohm, B, Ruczinski Ingo, Imboden, Medea, Gharib, Sina A, Wilk, Jemma B., Hansen, JG, Fall, Tove,, Franceschini, N. (Nora), Lahousse Lies, Kowgier Matthew, Foy Millennia, Hansel, Nadia N., Kurt Lohman (110218), O. Dale Williams (110242), Völzke, H. (Henry), Alanna C. Morrison (110248), Lenore J Launer, Gao Wei, Franceschini, N, Hansen, J., Hancock, D.B. (Dana), Probst-Hensch, NM, Morris, AP, Launer, Lenore J., R. Graham Barr, Couper David J., Gläser, S. (Sven), Li, G. (Guo), O. Connor, George T., Allerhand, M., Fernando Rivadeneira, Joubert, B.R. (Bonnie), Sina A. Gharib (63265), Eva Albrecht (174584), Heckbert Susan R., Imboden, M. (Medea), Dupuis, Josée, Gudnason, V. (Vilmundur), Gharib, S.A. (Sina), Williams, O.D. (Dale), Mathias, Rasika A., Morris, Andrew P, Tamara B. Harris (110195), Voorman Arend, Musk, Bill, Bonnie R. Joubert (110252), Probst-Hensch, Nicole M., Rotter, Jerome I, Gharib, S., Matthew Kowgier, Dana B. Hancock (110121), R. Graham Barr (109958), Lewis J. Smith, Franceschini, Nora, Hansen Joyanna G., Kathleen C. Barnes, Ruczinski, I. (Ingo), Soler Artigas, M., Loth, Daan W., Josée Dupuis, Alan James, Wei Gao (2085), Medea Imboden, Gharib Sina A., Gao, Wei, Lohman, K, Ruczinski, I, Wain, Louise V., Allerhand, M.M. (Michael), Lewis J Smith, Alan James, Rasika A. Mathias, Lohman Kurt, Wells, Martin T., Uitterlinden, A.G. (André), Andrew P Morris, Sood, A. (Akshay), George T O'Connor, McArdle, Wendy L., Barr, R. Graham, Dupuis, J, Palmer, Lyle J, Koch, B, Fall, M. (Magnus), Ian J Deary, Tobin, Martin D, Jemma B Wilk, Meibohm Bernd, Völzke, H, Davies, Gail, Artigas, Maria Soler, Lahousse, Lies, Morris, A.P. (Andrew), Melinda C Aldrich, Gudnason, V, Kumar, Ashish, Eva Albrecht, Rasika A Mathias, Gharib, SA, Wain, L.V. (Louise), Musk, A.W. (Arthur), Palmer, LJ, Franceschini Nora, Albert V Smith, Aldrich Melinda C., Uitterlinden, André G., Martin D Tobin, Guy G. Brusselle (110236), Smith Lewis J., Fall, T, Kowgier, M, Bruce M Psaty, Probst-Hensch Nicole M., Palmer, C. (Cameron), Smith, Albert V., Teumer, A, Soler Artigas, M. (Maria), Hodge, Emily, Nicole M Probst-Hensch, Morris, Andrew P., Gu, X, Louise V. Wain, Rotter Jerome I., Brusselle, G.G. (Guy), McArdle, W.L. (Wendy), Hall, IP, Meibohm, Bernd, Alanna C. Morrison, Psaty, B.M. (Bruce), Harris, TB, Kathleen C. Barnes (134420), Xiangjun Gu, Akshay Sood, Lind Lars, Lind, L, Harris, T., Daan W. Loth (110140), Curjuric, I. (Ivan), Mathias, J. (Jasmine), Starr, JM, Fall Tove, Li, Guo, Lumley, Thomas, Sven Gläser, Jemma B. Wilk, André G. Uitterlinden (2213413), Ian J. Deary, Lars Lind (88400), Barr, R., Smith, A.V. (Davey), Foy, M. (Millennia), Hofman, Albert, Deary, Ian J., Jerome I. Rotter (103729), Hansel, Nadia N, Yongmei Liu, Myriam Fornage, Cassano, Patricia A, James Alan, Teumer Alexander, Schulz Holger, André G. Uitterlinden, Xiangjun Gu (73651), Davies Gail, Tang, W, Brusselle, GG, Soler Artigas María, Bruno H. Stricker, Tang, Wenbo, Voelzke, Henry, Stricker, Bruno H., Ingelsson, E, Strachan, D.P. (David), Smith, A., Stephen B Kritchevsky, Dana B Hancock, Vilmundur Gudnason (8873), Strachan, DP, Lumley Thomas, Patricia A Cassano, Susan R. Heckbert (110293), Martin D. Tobin (110311), Andrew P. Morris, Imboden Medea, North, KE, Dupuis, J. (Josée), David J Couper, Bruno H. Stricker (336134), Rotter, JI, Davies, G. (Gail), Tove Fall, John M. Starr (107707), Lind, Lars,, Psaty, Bruce M., Wells, MT, Dupuis Josée, Lohman, Kurt, Hodge, E, Lars Lind, Gail Davies, Hancock Dana B., Gudnason, V., Hansen, Joyanna G, Henry Völzke, Bruce M. Psaty, Morrison, Alanna C, Tobin, MD, Wain, LV, Mathias, RA, Stricker, Bruno, Barr, RG, Wells, M.T. (Martin), Lies Lahousse, Alexander Teumer (112757), Lies Lahousse (548910), Strachan David P., Bill Musk, Palmer Lyle J., Schulz, H. (Holger), Strachan, David P, Schulz, H, Brusselle, Guy, Mathias, R., Stephen B. Kritchevsky, George T. O′Connor (591401), O′Connor, George T., Ian J. Deary (107724), Wendy L. McArdle (110155), Bill Musk (591400), Bernd Meibohm, Karrasch, S, Tove Fall (201258), Fornage Myriam, Hansen, J.G. (Joyanna), Teumer, A. (Alexander), Barr, R Graham, Voorman, J.M. (Jeanine), Ruczinski, Ingo, Hofman, Bert, Arend Voorman (221264), Lindgren, Cecilia, Stephen B. Kritchevsky (110259), Liu, Y. (YongMei), Bonnie R Joubert, Ingo Ruczinski (15765), David J. Couper (110257), Hansel, NN, Davies, G, V�lzke, Henry, Erik Ingelsson, Rasika A. Mathias (134405), Rotter, J.I. (Jerome), Psaty, Bruce M, Sven Gläser (110276), Koch Beate, Albrecht Eva, Aldrich, MC, Hancock, DB, Albrecht, E. (Eva), Heckbert, SR, Mathias Rasika A., North, Kari E., Wilk Jemma B., Probst-Hensch, N.M. (Nicole M.), Lumley, T, Aldrich, M., Kowgier, Matthew, Stefan Karrasch (412837), Ashish Kumar (152984), Rivadeneira Fernando, Wenbo Tang, Beate Koch (110151), Hansel, N., Fall, Tove, Albert V. Smith, Koch, B. (Beate), Tobin Martin D., Williams, O. Dale, Uitterlinden, André, Hancock, Dana B., Heckbert, S.R. (Susan), Ian P. Hall (110307), Karrasch, S. (Stefan), David P. Strachan, Kumar, A, Kritchevsky, SB, Nora Franceschini, Jemma B. Wilk (110164), Curjuric, Ivan, Emily Hodge (460149), Brusselle Guy G., Dana B. Hancock, North, K.E. (Kari), Vilmundur Gudnason, Andrew P. Morris (145709), Emily Hodge, Artigas, MS, Rivadeneira, Fernando, Aldrich, M.C. (Melinda), Bruno H Stricker, Loth, D.W. (Daan), Guy G. Brusselle, Stricker, B.H.Ch. (Bruno), Albert V. Smith (103644), Morrison, Alanna C., Stephanie J. London, Lewis J. Smith (156533), Stefan Karrasch, Loth, DW, Wilk, J.B. (Jemma), London, SJ, Curjuric Ivan, Launer Lenore J., Deary, IJ, Karrasch, Stefan, Lindgren Cecilia, Kathleen C Barnes, Völzke, Henry, Lyle J Palmer, Lindgren, C, Barnes, KC, Lenore J. Launer, Li, G, O'Connor, GT, Schulz, Holger, Lindgren, C.M. (Cecilia), Heinrich, J, Tang, W. (Wenbo), Barnes, K., Joubert, B., Bruce M. Psaty (103721), Loth, D., Uitterlinden, Andr� G., Nadia N Hansel, Gu, XJ, Millennia Foy (211777), Ivan Curjuric (110179), Nadia N. Hansel (359186), Hansen, Joyanna G., Susan R Heckbert, Sina A Gharib, Gläser, Sven, Cecilia Lindgren, McArdle Wendy L., Medea Imboden (110145), Thomas Lumley, Teumer, Alexander, Martin T. Wells (122541), Harris, Tamara B., London, Stephanie J, Albrecht, E., Joubert, BR, O?Connor, George T., Allerhand, M, Jerome I Rotter, David J. Couper, Wendy L. McArdle, Launer, LJ (Lenore), Gudnason, Vilmundur, Tang Wenbo, Martin T Wells, Smith, L.J. (Lewis), Lohman, K. (Kurt), Uitterlinden, André; id_orcid, Smith Albert V., Loth, Daan, Hall, Ian P, Barr R. Graham, Liu, Yongmei, Guo Li (174860), Nicole M. Probst-Hensch (110284), Wilk, JB, Kritchevsky Stephen B., Chen, Lin, Gail Davies (107670), Ivan Curjuric, Gudnason Vilmundur, Curjuric, I, Allerhand Michael, Sood Akshay, Lahousse, L, Lahousse, L. (Lies), Nicole M. Probst-Hensch, Soler Artigas, María, Williams, O Dale, Launer, L., Kumar Ashish, Guo Li, Gläser, S, Heinrich Joachim, Morrison, AC, Hofman, A. (Albert), Fornage, M. (Myriam), Albert Hofman, Hall Ian P., London, Stephanie J., Fornage, M, Harris Tamara B., Uitterlinden André G., Stricker Bruno H., Gharib, Sina A., André G Uitterlinden, North Kari E., Daan W. Loth, O Connor, George T, María Soler Artigas (110124), Hansel Nadia N., Gläser Sven, O'Connor, George T., Joyanna G Hansen, Wells Martin T., Smith, LJ, Lyle J. Palmer (95287), Gao, W. (Wei), McArdle, Wendy L, Foy, M, Ingelsson, E. (Erik), Deary Ian J., Kritchevsky, Stephen B, Lyle J. Palmer, Glaeser, Sven, Aldrich, Melinda C, Brusselle, Guy G, Liu Yongmei, Joubert, Bonnie R., Imboden, M, Barnes, Kathleen C., Ian P Hall, Alexander Teumer, Sood, Akshay, McArdle, WL, Couper, D.J. (David), Soler Artigas, M, Wain Louise V., Kari E North, Couper, David J, Starr, John M, Psaty, BM, Wenbo Tang, Albrecht, E, Louise V. Wain (110260), Hancock, Dana B, Li Guo, Koch, Beate, David P. Strachan (110302), Cassano, PA, Barnes Kathleen C., Joubert, Bonnie R, Stephanie J London, Ian P. Hall, Gu, X. (Xiangjun), Tang, W., Kritchevsky, Stephen B., Lind, L. (Lars), O. Dale Williams, Hofman, A, Lumley, T. (Thomas), Melinda C. Aldrich, Launer, L.J. (Lenore), James, A, Cassano Patricia A., Holger Schulz, Albert Hofman (107303), Voorman, Arend, O′Connor George T., Stricker, BH, Beate Koch, Launer, LJ, George T. O′Connor, Psaty Bruce M., Cassano, Patricia A., Wells, Martin T, Joachim Heinrich, Tang, WB, Ingelsson, Erik,, Barnes, K.C. (Kathleen), Albrecht, Eva, Hodge, E. (Emily), Hall, Ian P., Nora Franceschini (91434), Tobin, Martin D., Barr, R.G. (Graham), Wain, Louise V, Rotter, Jerome I., Kritchevsky, S.B. (Stephen), Joubert Bonnie R., Nadia N. Hansel, Wendy L McArdle, Millennia Foy, Williams, OD, Erik Ingelsson (232651), Kowgier, M. (Matthew), Patricia A. Cassano, Wilk, Jemma B, Meibohm, B. (Bernd), María Soler Artigas, Yongmei Liu (104713), Fernando Rivadeneira (61551), Kumar, A. (Ashish), Tang, Wenbo;Kowgier, Matthew;Loth, Daan W;Soler Artigas, Maria;Joubert, Bonnie R;Hodge, Emily;Gharib, Sina A;Smith, Albert V;Ruczinski, Ingo;Gudnason, Vilmundur;Mathias, Rasika A;Harris, Tamara B;Hansel, Nadia N;Launer, Lenore J;Barnes, Kathleen C;Hansen, Joyanna G;Albrecht, Eva;Aldrich, Melinda C;Allerhand, Michael;Barr, R Graham;Brusselle, Guy G;Couper, David J;Curjuric, Ivan;Davies, Gail;Deary, Ian J;Dupuis, Josée;Fall, Tove;Foy, Millennia;Franceschini, Nora;Gao, Wei;Gläser, Sven;Gu, Xiangjun;Hancock, Dana B;Heinrich, Joachim;Hofman, Albert;Imboden, Medea;Ingelsson, Erik;James, Alan;Karrasch, Stefan;Koch, Beate;Kritchevsky, Stephen B;Kumar, Ashish;Lahousse, Lies;Li, Guo;Lind, Lars;Lindgren, Cecilia;Liu, Yongmei;Lohman, Kurt;Lumley, Thomas;McArdle, Wendy L;Meibohm, Bernd;Morris, Andrew P;Morrison, Alanna C;Musk, Bill;North, Kari E;Palmer, Lyle J;Probst-Hensch, Nicole M;Psaty, Bruce M;Rivadeneira, Fernando;Rotter, Jerome I;Schulz, Holger;Smith, Lewis J;Sood, Akshay;Starr, John M;Strachan, David P;Teumer, Ale +617 more
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MutationalPatterns: comprehensive genome-wide analysis of mutational processes
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
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Genome-wide scanning versus candidate gene approach in the genetic architecture of common diseases. [PDF]
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