Results 231 to 240 of about 833,983 (263)

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

Genome-wide association studies identify 77 loci for suicidality and provide novel biological insights

Colbert SM, the Psychiatric Genomics Consortium Suicide Working Group, Ruderfer D, Docherty AR, Mullins N.   +4 more
europepmc   +1 more source

Realizing the promise of genome-wide association studies for effector gene prediction. [PDF]

Nat Genet
Costanzo MC, Harris LW, Ji Y, McMahon A, Burtt NP, Flannick J.   +5 more
europepmc   +1 more source

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink, Austin Wheeler, Bryant R. England, Solbritt Rantapää‐Dahlqvist   +3 more
wiley   +1 more source

Emanating candidate genes responsible for fruit quality traits in citrus through GBS-based genome wide association studies. [PDF]

BMC Genomics
Bala H, Kaur M, Manchanda P, Uppal GS, Malik P, Sidhu GS, Vikal Y.   +6 more
europepmc   +1 more source

Associations of Sleep and Shift Work with Osteoarthritis Risk

Arthritis Care &Research, Accepted Article.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships between circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000‐person cohort, we evaluated associations between sleep duration, sleeplessness/insomnia, and ...
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

Genome-wide association studies reveal genetic diversity and regulatory loci underlying dwarfing traits in banana. [PDF]

J Integr Plant Biol
Li Y, Feng J, Yan L, Wei S, Hu H, Liu J, Xie Y, Cai B, Li K, Zhao Y, Chen Y, Cheng Q, Cao M, Wang Y, Wei Y, Li W, Wang W, Xie J, Han Z.   +18 more
europepmc   +1 more source

Data simulation to optimize frameworks for genome-wide association studies in diverse populations. [PDF]

Front Genet
Mugo JW, Mulder N, Chimusa ER.
europepmc   +1 more source

Genetic Architecture of Ischemic Stroke: Insights from Genome-Wide Association Studies and Beyond. [PDF]

J Cardiovasc Dev Dis
Jagodic A, Zivalj D, Krsek A, Baticic L.
europepmc   +1 more source

Editorial: Advancements and prospects of genome-wide association studies. [PDF]

Front Genet
Doumatey AP, Li Y, Fernandez-Lopez JC.
europepmc   +1 more source