Results 241 to 250 of about 833,983 (263)

The Impact of Ancestry on Genome-Wide Association Studies. [PDF]

open access: yesPac Symp Biocomput
Jones SC   +4 more
europepmc   +1 more source

Extending Genome-Wide Association Studies to admixed cohorts with high degrees of relatedness

open access: yes
Tan T   +13 more
europepmc   +1 more source

Genome-wide association studies of Long COVID and post-acute complications of SARS-CoV-2 in the UK Biobank Data

open access: yes
Prieto-Alhambra D   +6 more
europepmc   +1 more source
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Genome-Wide Association Studies

JAMA, 2019
Abstract Genome-wide association studies (GWAS) have evolved over the past ten years into a very successful tool for investigating the genetic architecture of multifactorial human traits and disorders. One major advantage of GWAS is that they do not require any a priori knowledge about the biological mechanisms underlying the traits and ...
Xiuqing, Guo, Jerome I, Rotter
  +6 more sources

Genome-Wide Association Studies

2010
Genome-wide association (GWA) studies are best understood as an extension of candidate gene association studies, scaled up to cover hundreds of thousands of markers across the genome in samples usually of several thousand cases and controls. The GWA approach allows the detection of much smaller effect sizes than with previous linkage-based genome-wide ...
Paola Sebastiani, Nadia Solovieff
  +5 more sources

Genome-Wide Association Studies (GWAS)

2023
Most of the breeding targets are quantitative traits. In exploring the quantitative trait locus (QTL) system of a trait, linkage mapping was established using sparse polymerase chain reaction (PCR) markers. With the genome-wide sequencing technology advanced, genome-wide association study (GWAS) was developed for natural (germplasm) populations using ...
Jianbo, He, Junyi, Gai
openaire   +2 more sources

Genome-Wide Association Studies

2012
A host of data on genetic variation from the Human Genome and International HapMap projects, and advances in high-throughput genotyping technologies, have made genome-wide association (GWA) studies technically feasible. GWA studies help in the discovery and quantification of the genetic components of disease risks, many of which have not been unveiled ...
Tun-Hsiang, Yang   +2 more
openaire   +3 more sources

Family-Based Genome-Wide Association Studies

Pharmacogenomics, 2009
In the last 2 years, the effort to identify genes affecting common diseases and complex traits has been accelerated through the use of genome-wide association studies (GWAS). The availability of existing large collections of linkage data paved the way for the use of family-based GWAS.
Benyamin, Beben   +2 more
openaire   +4 more sources

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