Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders
Abstract Background Evidence indicates substantial genetic overlap between psychiatric diagnoses. Accounting for these transdiagnostic effects can sharpen research on disorder‐specific genetic architecture and patterns of comorbidity. Methods We applied genomic structural equation modeling to genome‐wide association study summary statistics from 11 ...
Engin Keser +6 more
wiley +1 more source
Assessing genetic diversity and performing genome-wide association studies (GWAS) using multiple marker types across desi, kabuli, and wild accessions in chickpea (Cicer arietinum L.). [PDF]
Ruperao P +7 more
europepmc +1 more source
A BAYESIAN GRAPHICAL MODEL FOR GENOME-WIDE ASSOCIATION STUDIES (GWAS). [PDF]
Briollais L +5 more
europepmc +1 more source
Genome-wide association study (GWAS) datasets used in the study.
Genome-wide association study (GWAS) datasets used in the study.
Zhekang Liu (17941199) +2 more
core +1 more source
Abstract Background Attention‐deficit/hyperactivity disorder (ADHD) and language/reading difficulties frequently co‐occur. The extent of shared genetic architecture remains incompletely defined. We investigated genome‐wide overlap between ADHD and four core skills: word reading, nonword reading, spelling, and phoneme awareness.
Jinzhu Zhao +5 more
wiley +1 more source
Advancements and Prospects of Genome-Wide Association Studies (GWAS) in Maize. [PDF]
Sahito JH +7 more
europepmc +1 more source
The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog). [PDF]
MacArthur J +16 more
europepmc +1 more source
Technological advancements in functional interpretation of genome-wide association studies (GWAS) findings: bridging the gap to clinical translation. [PDF]
Aherrahrou R, Kaikkonen MU.
europepmc +1 more source
Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang +3 more
wiley +1 more source
Genome-Wide Association Studies (GWAS) and Transcriptome Analysis Reveal Male Heterogametic Sex-Determining Regions and Candidate Genes in Northern Snakeheads (Channa argus). [PDF]
Liu H +9 more
europepmc +1 more source

