Results 171 to 180 of about 189,144 (345)

Young adult self‐harm: The role of victimisation and polygenic risk in a population‐based longitudinal study

JCPP Advances, EarlyView.
Abstract Background Victimisation has been associated with self‐harm (with or without suicidal intent), but little is known about this association during young adulthood—a distinct developmental period. Further, not all individuals who experience victimisation will later engage in self‐harm, suggesting the influence of other factors.
Filip Marzecki, Isabelle Ouellet‐Morin, Helena M. S. Zavos, Sylvana Côté, Richard E. Tremblay, Jean‐Philippe Gouin, Massimiliano Orri, Michel Boivin, Marie‐Claude Geoffroy   +8 more
wiley   +1 more source

Protocols, Methods, and Tools for Genome-Wide Association Studies (GWAS) of Dental Traits. [PDF]

Methods Mol Biol, 2019
Agler CS, Shungin D, Ferreira Zandoná AG, Schmadeke P, Basta PV, Luo J, Cantrell J, Pahel TD, Meyer BD, Shaffer JR, Schaefer AS, North KE, Divaris K.   +12 more
europepmc   +1 more source

Genome-Wide Association Studies (GWAS) breast cancer susceptibility loci in Arabs: susceptibility and prognostic implications in Tunisians [PDF]

, 2012
Jingxuan Shan, Wijden Mahfoudh, Shoba P. DSouza, Elham Hassen, Noureddine Bouaouina, Sonia Abdelhak, Ahlem Benhadjayed, Hager Memmi, Rebecca Mathew, Idil I. Aigha, Sallouha Gabbouj, Yassmine Remadi, Lotfi Chouchane   +12 more
openalex   +1 more source

Investigating the impact of early adversity on perceived support from parents and friends in preadolescence: Do genetic predispositions and timing of exposure matter?

JCPP Advances, EarlyView.
This study found that youth with a higher genetic risk for internalizing and externalizing problems were more likely to face adversity within their home, highlighting the need for risk mitigation. These associations varied by adversity type and timing. Additionally, low family income, parental divorce, and externalizing behaviours were linked to lower ...
Christina Y. Cantave, Marthe de Roo, Charlotte Vrijen, Tina Kretschmer   +3 more
wiley   +1 more source

Unpacking early risks for peer victimization: A network analysis of early temperament and polygenic risk scores

JCPP Advances, EarlyView.
Abstract Background Children who show difficult temperament are at risk of peer victimisation, which in turn associates with numerous negative outcomes later in life. We used network analysis to examine whether specific aspects of difficult temperament contributed to these associations, and whether the links were moderated by variations in genetic ...
Tom C.‐H. Wu, Deniz Konac, Liliana Garcia‐Mondragon, Alex F. Martin, Barbara Maughan, Ted Barker   +5 more
wiley   +1 more source

Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders

JCPP Advances, EarlyView.
Abstract Background Evidence indicates substantial genetic overlap between psychiatric diagnoses. Accounting for these transdiagnostic effects can sharpen research on disorder‐specific genetic architecture and patterns of comorbidity. Methods We applied genomic structural equation modeling to genome‐wide association study summary statistics from 11 ...
Engin Keser, Wangjingyi Liao, Andrea G. Allegrini, Kaili Rimfeld, Thalia C. Eley, Robert Plomin, Margherita Malanchini   +6 more
wiley   +1 more source

GWAS-Flow : A GPU accelerated framework for efficient permutation based genome-wide association studies [PDF]

, 2019
Jan A. Freudenthal, Markus J. Ankenbrand, Dominik G. Grimm, Arthur Korte   +3 more
openalex   +1 more source

Insect‐resistant soybean genotypes accumulate rutin and its O‐methylated derivative narcissin, a more potent flavonol targeting Anticarsia gemmatalis digestive and detoxification enzymes and reducing larval survival

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Soybean underpins Brazil's agricultural, yet its sustainability is threatened by lepidopteran pests such as Anticarsia gemmatalis. Although insect‐resistant cultivars have long been associated with the constitutive accumulation of quercetin‐derived flavonols, the biochemical mechanisms underlying this resistance remain poorly ...
Jessica Nunes de Assis, Valquira Joana Medina Pinheiro, Jodieh Oliveira Santana Varejão, Ian de Paula Alves Pinto, André Luiz Lourenção, Nathália Silva Oliveira, Giovanna Cassia Mendes Moraes, Eduardo Vinícius Vieira Varejão, Maria Goreti de Almeida Oliveira, Humberto Josué de Oliveira Ramos   +9 more
wiley   +1 more source

Assessing the suitability of formalin-fixed paraffin-embedded (FFPE) tissue for genome-wide association studies (GWAS). [PDF]

BMC Res Notes
Reingruber J, Krämer MJ, Bigge J, Dasmeh P, Grover S, Heilmann-Heimbach S, Nöthen MM, Kreuser N, Gockel I, Veits L, Vieth M, Jank P, Denkert C, Maj C, Hess T, Schumacher J.   +15 more
europepmc   +1 more source

How genome-wide association studies (GWAS) made traditional candidate gene studies obsolete. [PDF]

Neuropsychopharmacology, 2019
Duncan LE, Ostacher M, Ballon J.
europepmc   +1 more source