Results 241 to 250 of about 189,144 (345)

GWAS and genomic prediction of crown rust resistance in the southern US elite oat (Avena sativa L.) germplasm. [PDF]

Plant Genome
Acharya JP, Babar MA, Klos KE, Harrison S, DeWitt N, Ibrahim AMH, Murphy P, Nandety RS, Fiedler J.   +8 more
europepmc   +1 more source

Metabolome Diversity Enhances Resistance of Intertidal Clams to Thermal Stress

Integrative Zoology, EarlyView.
Meretrix species are widely distributed intertidal bivalves in China with significant ecological and economic importance, which are sensitive to thermal stress. Our results showed that thermal environments of clam habitats shaped metabolome diversity, which can enhance the resistance of intertidal clams to thermal stress.
Zhi Hu, Xiang‐Tao Wei, Xiaonie Lin, Linxuan Ma, Tianzhe Zhang, Yunwei Dong   +5 more
wiley   +1 more source

Genome-Wide Cross-Trait Analysis Dissects the Shared Genetic Architecture Between Type 2 Diabetes Mellitus and Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]

Hum Mutat
Zhu Z, Li H, Wang X, Chen X, Cheng L.
europepmc   +1 more source

Bidirectional genetic and phenotypic links between smoking and striatal iron content involving dopaminergic and inflammatory pathways

Addiction, EarlyView.
Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova, Ilaria Iuliani, Sven Bergmann   +2 more
wiley   +1 more source

Obstructive Sleep Apnea and Female Reproductive Endocrine Diseases: A Mendelian Randomization and Mediation Analysis. [PDF]

Int J Endocrinol
Wang Z, Qin J, Wang J, Chen Z, Qiao Z, Yan M, Wu D.   +6 more
europepmc   +1 more source

Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses. [PDF]

Alcohol Clin Exp Res, 2015
Hart AB, Kranzler HR.
europepmc   +1 more source

Associations of cannabis use, tobacco use and co‐use with brain volume: A systematic review and meta‐analysis

Addiction, EarlyView.
Abstract Background and aims Cannabis is the most widely used illicit drug worldwide and is often co‐used with tobacco, the leading cause of preventable death. Although cannabis and tobacco have distinct neurobiological actions, their associations with brain volumes are unclear.
Katherine Sawyer, Tom P. Freeman, Martine Skumlien, Esther Walton, Thomas Lancaster, Jorien L. Treur, Valentina Lorenzetti, Anna K. M. Blackwell, Chloe Burke, Richie J. Carr, Constantinos Constantinides, Maisie Cox, Sarah Dance, Shadi Daryan, Sorcha Hamilton, Tom Jenkins, Gemma M. J. Taylor   +16 more
wiley   +1 more source

Ordinal GWAS analysis of the frailty phenotype identified a novel locus at 12q22 that underscores the role of the neurological and immune systems. [PDF]

NPJ Aging
Borhan S, An Nguyen LM, Pigeyre M, Pare G, Adachi J, Papaioannou A, Griffith LE, Thabane L, Raina P.   +8 more
europepmc   +1 more source

A genetically informed cross‐lagged twin study of the longitudinal association between addiction‐related behaviors and obesity

Addiction, EarlyView.
Abstract Background and aims Addiction‐related behaviors, such as loss of control eating (LOC), cigarette smoking and alcohol consumption, have been associated with high body mass index (BMI). This study aimed to assess genetic and environmental contributions to these associations over time.
Baiyu Qi, Heather M. Highland, Mariaelisa Graff, Cynthia M. Bulik, Soo Hyun Rhee, Michael C. Stallings, John K. Hewitt, Daniel E. Gustavson, Chandra A. Reynolds, Kari E. North, Melissa A. Munn‐Chernoff   +10 more
wiley   +1 more source

Genome-wide fine-mapping improves identification of causal variants. [PDF]

Nat Genet
Wu Y, Zheng Z, Thibaut L, Lin T, Feng Q, Cheng H, Yengo L, Goddard ME, Wray NR, Visscher PM, Zeng J.   +10 more
europepmc   +1 more source