Results 131 to 140 of about 674,070 (352)

Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain [PDF]

, 2020
Md Shafiqur Rahman, Bendik S Winsvold, S.O. Chavez Chavez, Sigrid Børte, Yakov A. Tsepilov, Sodbo Zh. Shapov, Yurii S. Aulchenko, Knut Hagen, Egil A. Fors, Kristian Hveem, John‐Anker Zwart, Joyce B. J. van Meurs, Maxim B. Freidin, Frances M. K. Williams, Frances M.K. Williams   +14 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Replication of the Wellcome Trust genome-wide association study of essential hypertension: the Family Blood Pressure Program [PDF]

, 2008
Georg Ehret, Alanna C. Morrison, Ashley O’Connor, Megan L. Grove, Lisa Baird, Karen Schwander, Alan B. Weder, Stephen S. Rich, D. C. Rao, Steven C. Hunt, Eric Boerwinkle, Aravinda Chakravarti   +11 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Nature, 2007
P. Burton, D. Clayton, L. Cardon, N. Craddock, P. Deloukas, A. Duncanson, D. Kwiatkowski, M. McCarthy, W. Ouwehand, N. Samani, J. Todd, P. Donnelly, J. Barrett, D. Davison, D. Easton, David Evans, H. Leung, J. Marchini, A. Morris, C. Spencer, M. Tobin, A. Attwood, J. Boorman, B. Cant, Ursula Everson, Judith M. Hussey, J. Jolley, A. S. Knight, K. Koch, Elizabeth Meech, S. Nutland, C. Prowse, H. Stevens, N. Taylor, G. Walters, N. Walker, N. Watkins, T. Winzer, Richard W Jones, W. McArdle, S. Ring, D. Strachan, M. Pembrey, G. Breen, D. Clair, S. Caesar, K. Gordon-Smith, L. Jones, C. Fraser, E. Green, D. Grozeva, M. Hamshere, P. Holmans, I. Jones, G. Kirov, V. Moskvina, I. Nikolov, M. O’Donovan, M. Owen, D. Collier, A. Elkin, A. Farmer, R. Williamson, P. McGuffin, A. Young, I. Ferrier, S. Ball, A. Balmforth, J. Barrett, D. Bishop, M. Iles, A. Maqbool, N. Yuldasheva, A. Hall, P. Braund, R. Dixon, M. Mangino, Suzanne E Stevens, J. Thompson, F. Bredin, M. Tremelling, M. Parkes, H. Drummond, C. Lees, E. Nimmo, J. Satsangi, S. Fisher, A. Forbes, C. Lewis, Clive M. Onnie, N. Prescott, J. Sanderson, C. Mathew, J. Barbour, M. Mohiuddin, C. Todhunter, J. Mansfield, T. Ahmad, Fraser Cummings, D. Jewell, J. Webster, Morris J. Brown, G. Lathrop, J. Connell, A. Dominiczak, C. Marcano, B. Burke, R. Dobson, J. Gungadoo, Kate L. Lee, P. Munroe, S. Newhouse, Abiodun K Onipinla, C. Wallace, M. Xue, M. Caulfield, M. Farrall, A. Barton, I. Bruce, Hannah Donovan, S. Eyre, Paul D. Gilbert, S. Hider, A. Hinks, S. John, C. Potter, A. Silman, D. Symmons, W. Thomson, Jane Worthington, D. Dunger, B. Widmer, T. Frayling, R. Freathy, H. Lango, J. Perry, B. Shields, M. Weedon, A. Hattersley, G. Hitman, M. Walker, K. Elliott, C. Groves, C. Lindgren, N. W. Rayner, N. Timpson, E. Zeggini, M. Newport, G. Sirugo, Emily J. Lyons, F. Vannberg, A. Hill, L. Bradbury, C. Farrar, J. J. Pointon, Paul Wordsworth, M. Brown, J. Franklyn, J. Heward, M. Simmonds, S. Gough, S. Seal, M. Stratton, N. Rahman, M. Ban, A. Goris, S. Sawcer, Alastair Compston, D. Conway, M. Jallow, K. Rockett, S. Bumpstead, Amy Chaney, K. Downes, Mohammed J. R. Ghori, R. Gwilliam, S. Hunt, M. Inouye, A. Keniry, E. King, R. McGinnis, Simon C. Potter, R. Ravindrarajah, P. Whittaker, Claire Widden, D. Withers, Niall J. Cardin, T. Ferreira, Joanne Pereira-Gale, Ingileif B. Hallgrímsdóttir, Bryan N. Howie, Z. Su, Y. Teo, Damjan Vukcevic, D. Bentley, A. Compston   +195 more
semanticscholar   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Deciphering the Genetic Basis of Allelopathy in japonica Rice Cultivated in Temperate Regions Using a Genome-Wide Association Study

Rice
Allelopathy has been considered as a natural method of weed control. Despite the nature of allelochemical compounds has been studied, little is known about the genetic basis underlying allelopathy.
Julia García-Romeral, Raúl Castanera, Josep Casacuberta, Concha Domingo   +3 more
doaj   +1 more source

A genomic analysis of twinning rate and its relationship with other reproductive traits in Holstein-Friesian cattle

Journal of Dairy Science
: Twin births in dairy cattle is generally unfavorably associated with reproductive performance and calf survival in dairy cows. Genetic selection to reduce twinning rate in dairy cattle may be desirable, provided no undesirable correlated responses in ...
Brian W. Kirkpatrick, Donagh P. Berry
doaj   +1 more source

Redundancy analysis, genome‐wide association studies and the pigmentation of brown trout (Salmo trutta L.)

, 2022
Théo Valette, Maëva Leitwein, J. M. LASCAUX, Érick Desmarais, Patrick Berrebi, Bruno Guinand   +5 more
openalex   +2 more sources

Genome-Wide Association Study Detects Loci Involved in Scab Susceptibility in Japanese Apricot [PDF]

, 2023
Koji Numaguchi, Tomoaki Kashiwamoto, Ryo Ishikawa, Takashige Ishii, Yuto Kitamura   +4 more
openalex   +1 more source