Results 121 to 130 of about 40,713,960 (307)
Unraveling genotype–phenotype relationships in hereditary hemochromatosis through integrated biobank data analysis
BMC GenomicsBackground Type I hereditary hemochromatosis (HH), caused by pathogenic HFE variants, is among the most common autosomal recessive disorders in Northern Europe.Miriam Nurm, Tarmo Annilo, Sebastian May-Wilson, Anu Reigo, Reedik Mägi, Urmo Võsa, Neeme Tõnisson, Estonian Biobank Research Team, Toomas Haller +8 moredoaj +1 more source‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...Jack P. K. Bravowiley +1 more sourceGenetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies [PDF]
, 2012 <p>Background - Various genome-wide association studies (GWAS) have been done in ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have been 3500 cases or less.Furie, K., Benn, M. (Marianne), Carty, C., Reiner, AP, Palmer, Colin N.A., Markus, Hugh S, Lindgren, Arne,, Fornage, Myriam, Algra, Ale, Nalls, Mike A, de Bakker, P.I.W., Rothwell, Peter M., Worrall, Bradford B, Nalls, Mike A., Kuhlenbaeumer, Gregor, Deary, Ian, Levi, C., Palmer, Colin N. A., Delavaran, Hossein,, Berger, K., Reiner, A.P., Sharma, P, The Australian Stroke Genetics Collaborative, including Jonathan Golledge, Higgins, P., Palmer, CN, Worrall, BB, Vicente, A.M. (Astrid M), Helgadottir, A, Thorleifsson, G. (Gudmar), Rothwell, Peter M, Kuhlenbäumer, G., Pandolfo, M, Khan, M.I. (Muhammad), Khan, M.S., Stefansson, K, Wiggins, Kerri L., Lindgren, Arne, Vicente, Astrid M., Hofman, A., Bis, JC, Kittner, Steven J., Kittner, Steven, Boncoraglio, G. (Giorgio Battista), Schmidt, Reinhold, Palmer, C.N.A. (Colin), Nordestgaard, Børge G., Paré, Guillaume, Wiggins, K.L. (Kerri), Delavaran, H, de Bakker, Paul I. W., Cheng, Y.-C. (Yu-Ching), Sale, P. (Patrizio), Cheng, YC, Wiggins, K.L., Meschia, JF, Pandolfo, M. (Massimo), Levi, C, Sudlow, C. (Cathie), Saleheen, D, ?, ?, Ringelstein, E.B., Fomage, Myriam, Bevan, S, Wiggins, KL, Gretarsdottir, S. (Solveig), Zwart, J-A. (John-Anker), Nordestgaard, B.G., Deary, I.J. (Ian), Kuhlenbäumer, G, Mosley, Thomas H, Paré, G., Nalls, M.A., Algra, A. (Ale), Hopewell, Jemma C., Oliveira, SA, Berger, K. (Klaus), Traylor, M, Seshadri, S., Boncoraglio, G.B., Valdimarsson, Einar, Wiggins, Kerri L, van Zuydam, Natalie R., Lemmens, Robin, Carty, Cara, Worrall, B.B. (Bradford B.), Fernandez-Cadenas, I. (Israel), Benn, M, Achterberg, Sefanja, Vicente, Astrid M, Thijs, V, Ikram, M Arfan, Doney, AS, Dichgans, M, Zuydam, N.R. van, Wellcome Trust Case Control Consortium 2 (WTCCC2), Norrving, Bo,, Bakker, P.I.W. (Paul) de, Furie, K.L. (Karen), Nalls, M.A. (Michael), Yadav, S, Fernandez-Cadenas, I., Longstreth, W.T., Paré, G. (Guillaume), Mitchell, BD, Bakker, P.I.W. de, Norrving, B., Holliday, Elizabeth G., van Zuydam, N.R., Achterberg, S, van Zuydam, N.R,, Traylor, Mathew, Reiner, Alex P, Sharma, Pankaj, Montaner, J., Rothwell, PM, Kee, Weang, O'Donnell, M., Carty, C. (Cara), Cheng, Yu-Ching, Carty, C, Lund University., Rothwell, P.M. (Peter), Pandolfo, Massimo, Schmidt, Helena, Int Stroke Genetics Consortium, Norrving, Bo, de Bakker, Paul I W, Davies, Gail, Chen, W-M., Gretarsdottir, S., Gschwendtner, A., Bevan, Steve, Cheng, Y.-C., Abboud, S, Sharma, P. (Pankaj), Doney, Alexander S.F.; id_orcid, Norrving, B. (Bo), Benn, M., Ferro, Jose M., Slowik, A, Walters, Matthew, Yadav, S. (Sunaina), Delavaran, H. (Hossein), Holliday, E.G., Lindgren, A. (Arne), Meschia, James F, Farrall, M. (Martin), Pera, J, Longstreth, W. T., Oliveira, Sofia A., Helgadottir, H.T. (Hafdis), Ferro, Jose M, Reiner, Alex P., Slowik, A., Ringelstein, E.Bernd, Thorsteinsdottir, U, International Stroke Genetics Consortium, Sudlow, C., Longstreth, W, Chen, W.M., Malik, R. (Rainer), Mosley, Thomas H., Markus, H.S., Thorsteinsdottir, U. (Unnur), Abboud, S., Psaty, B.M. (Bruce), Mosley, T.H., Thijs, Vincent, Ikram, Arfan, Saleheen, D., Walters, M.R. (Matthew), Traylor, M., de Bakker, P.I., Montaner, J, O'Donnell, M, Oliveira, Sofia A, Ho, W.K., Kostulas, Konstantinos, Hofman, Albert, Palmer, CNA, Levi, C. (Christopher), Chen, W.-M., Higgins, P, Bevan, S., Longstreth Jr, W.T., Doney, A.S., Mitchell, B.D. (Braxton), Seshadri, S. (Sudha), Sale, M, Ho, WK, Furie, Karen, Delavaran, H., Sale, M., Valdimarsson, E, Cheng, Y.C., Slowik, A. (Agnieszka), DeStefano, A.L. (Anita), Rosand, J. (Jonathan), Davies, G. (Gail), Helgadottir, Anna, Psaty, Bruce M., O'Donnell, M. (Martin), Australian Stroke Genetics Collaborative, Wellcome Trust Case Co, Mitchell, Braxton D., Walters, M., Doney, ASF, van Zuydam, Natalie R, de Bakker, PIW, Rosand, Jonathan, Holliday, Elizabeth G, Fernandez-Cadenas, I, Bis, Joshua C, Delavaran, Hossein, Bevan, S. (Steve), Achterberg, S. (Sefanja), Valdimarsson, E. (Einar), Lemmens, R, Bis, J.C. (Joshua), Benn, Marianne, Parati, E.A., Kubisch, C. (Christian), Gschwendtner, A. (Andreas), Hofman, Bert, Farrall, M, Montaner, J. (Joan), Meschia, J.F. (James F.), Khan, Muhammad Saleem, Kittner, Steven J, Levi, Christopher, Sudlow, Catherine; id_orcid, Davies, G, Palmer, C.N.A., Oliveira, S.A. (Sofia), Psaty, Bruce M, Rothwell, P.M., Pera, M.F. (Martin ), Parati, E.A. (Eugenio), Oliveira, S.A., Furie, K, Dichgans, M., van Zuydam, NR, Boncoraglio, Giorgio B, Kittner, S, Berger, Klaus, Pera, Joanna, Davies, G., Higgins, P. (Peter), Pandolfo, M., Holliday, EG, Valdimarsson, E., Rosand, J., Palmer, Colin N A, Ho, Weang Kee, Deary, I., Bis, J.C., Lemmens, R., Clarke, Robert, Boncoraglio, Giorgio B., Sudlow, C, Kuhlenbäumer, G. (Gregor), Schmidt, H., Abboud, Sherine, Ferro, M.T. (María), Australian Stroke Genetics Collabo, Higgins, Peter, Worrall, Bradford B., Mitchell, Braxton D, Malik, R., Boncoraglio, GB, Lindgren, A, Clarke, R., Thorsteinsdottir, Unnur, Fornage, M., Mosley, TH, Ringelstein, E Bernd, Parati, Eugenio A, DeStefano, A.L., Lemmens, R. (Robin), Stefansson, K., Markus, HS, Chen, Wei-Min, Doney, Alexander S. F., Ringelstein, EB, Bis, Joshua C., Ikram, M.A., Rosand, J, Ferro, J. M., Norrving, B, Farrall, M., Seshadri, S, International Stroke Genetics Consortium., Walters, Mathew, Kostulas, K. (Konstantinos), Thorleifsson, G, Doney, Alexander S.F., Malik, R, Destefano, AL, Slowik, Agnieszka, Thijs, V. (Vincent), Lindgren, A., Longstreth, Wt, Nordestgaard, B.G. (Børge), Clarke, R. (Robert), Stefansson, Kan, Kostulas, K., Destefano, Anita L, Schmidt, R, Fomage, M., Farrall, Martin, Ferro, J.M., Schmidt, R. (Reinhold), Schmidt, H, WTCCC 2, Palmer, Colin N.A.; id_orcid, Helgadottir, A., Fernandez-Cadenas, Israel, Stefansson, Kari, Nordestgaard, BG, Ikram, M. Arfan, Sharma, P., Abboud, S. (Shimon), Clarke, R, Parati, EA, Gretarsdottir, Solveig, Berger, K, Hofman, A. (Albert), Palmer, C.N., Kittner, S., Algra, A, Fornage, M. (Myriam), Ringelstein, E.B. (E. Bernd), Nalls, MA, Fornage, M, O'Donnell, Martin, Longstreth, W., Kittner, T. (Thomas), Algra, A., Thorsteinsdottir, U., Kittner, S.J., Sale, Michele, Fomage, M, Reiner, A. (Alexander), Kittner, SJ, Ikram, MA, Deary, I, Worrall, B.B., Ferro, JM, Gschwendtner, Andreas, Dichgans, Martin, Holliday, E.G. (Elizabeth), Thorleifsson, G., Gschwendtner, A, Schmidt, R., de Bakker, Paul I.W., Nordestgaard, Børge G, Traylor, M. (Matthew), Mosley, T.H. (Thomas), DeStefano, Anita L., Doney, A.S.F. (Alex), Nordestgaard, Borge G., Thorleifsson, Gudmar, Yadav, S., Kostulas, K, Vicente, A.M., Australian Stroke Genetics Collaborative, Wellcome Trust Case Control Consortium 2 (WTCCC2), Psaty, BM, de Bakker, PI, Parati, Eugenio A., Saleheen, Danish, Khan, MS, Vicente, AM, Walters, M, Psaty, B.M., Hofman, A, Hopewell, Jemma C, Meschia, J.F., Pera, J., Doney, A.S.F., Mitchell, B.D., Markus, Hugh S., Kuhlenbäumer, Gregor, Hopewell, JC, Zuydam, N.R. (Natalie) van, Chen, WM, Thijs, V., Gretarsdottir, S, Yadav, Sunaina, Markus, H.S. (Hugh), Hopewell, J., Ringelstein, E. Bernd, Sudlow, Cathie, Paré, G, Montaner, Joan, Ho, W.K. (Weang Kee), Achterberg, S., Doney, Alexander S F, Seshadri, Sudha, Hopewell, J.C., Meschia, James F., Ikram, M.A. (Arfan), Malik, Rainer, Hopewell, Jemma, Traylor, Matthew, Cheng, Y-C +403 morecore +2 more sourcesChapter 11: Genome-Wide Association Studies
PLoS Computational Biology, 2012 Genome-wide association studies (GWAS) have evolved over the last ten years into a powerful tool for investigating the genetic architecture of human disease. In this work, we review the key concepts underlying GWAS, including the architecture of common diseases, the structure of common human genetic variation, technologies for capturing genetic ...William S. Bush, Jason H. Mooreopenaire +5 more sourcesGenome-wide association and functional follow-up reveals new loci for kidney function [PDF]
, 2012 Chronic kidney disease (CKD) is an important public health problem with a genetic component. We performed genome-wide association studies in up to 130,600 European ancestry participants overall, and stratified for key CKD risk factors. We uncovered 6 new Döring, Angela, Atkinson, Elizabeth J, Gary C Curhan, Wichmann HE, Thun, G.-A., Trompet, S., Heid, I. M., Goessling Wolfram, Kroemer H.K., Boerwinkle, E., Kähönen M., Wilson J.F., Franke A., Biffar Reiner, Palmer, C., Zemunik T, Toshiko Tanaka, Rettig Rainer, Rao, Madhumathi, Toniolo, D. (Daniela), Smith, AV, Liu C.-T., Harshal Deshmukh, Curhan, G. C., Foster, Meredith C, Taliun, D, Heid Iris M., Gao, XY, Ridker P., Glazer, N., Fox Caroline S., Liu, Ching-Ti, Struchalin, M.V. (Maksim), Trompet, S. (Stella), O´Connell, J.R., Böger C.A., Chu, A.Y., de Andrade M, Smith AV, Fuchsberger Christian, Krämer, B.K., Hwang, S. J., Atkinson, Elizabeth J., Igl, W., Harris, T.B. (Tamara), Jingzhong Ding, Turner ST, Vollenweider Peter, Voelker, Uwe, Adrienne Tin (160761), Toniolo, D, J. Wouter Jukema (127361), Johnson, A.D. (Andrew), Vincent Chouraki, Uitterlinden A.G., Gorski, M. (Mathias), Adam M, Andrews JS, Rivadeneira, F, Turner, S. T., Wheeler, H.E., Gyllensten, Ulf,, Turner, ST, Rao M, Henry Völzke (64286), Meredith C. Foster (165430), Tin, A., Florian Kronenberg (87557), Andrews, J.S. (Jeanette), Nikopensius, Tiit, Shuldiner AR, Rudan, I. (Igor), Jie Jin Wang (103779), Borecki, I, Freedman, BI, Portas L, Ulivi, S, Nauck, Matthias, et al., Rao Madhumathi, Smith, A.V. (Albert Vernon), Stumvoll Michael, Ketkar S, Imboden, Medea, Peter P. Pramstaller (150111), Trompet S., Gudny Eiriksdottir (8872), Doney, A., Hastie N., Karlhans Endlich, Illig T, Vitart, Veronique, Homuth, G. (Georg), Rao M., Johansson, Åsa,, Kolcic, I. (Ivana), O'Seaghdha, Conall, Kähönen, M., Ketkar, S, Cavalieri, M., Probst-Hensch, NM, Wright, A.F., Gao, X., Deshmukh H, Minelli, Cosetta, Gasparini P., Chu, AY, Ciullo, M., Conall M O'Seaghdha, Ulf Gyllensten, Li, M. (Man), Probst-Hensch, Nicole M., Paulweber, B, Wild, S.H. (Sarah), Robino, A, Atkinson EJ, Rettig R, Buckley, B.M., Dehghan A, Johansson, Å, Illig, T., Yang, Q., Franke, Andre, Wang, J.J. (Jie Jin), Adam M., Biffar R., Colhoun, H., Cornelis MC, Curhan GC, Kolcic Ivana, Thun, G.A., Borecki I, Ding, JZ (Jing Zhong), Tönjes A., Tönjes, A. (Anke), Ding Jingzhong, Iris M Heid, Völzke, H, Kim, SK, Lohman K, Kroemer, H. K., Thun, G. A., Liu, CT, Hofman A, Köttgen, Anna, Qiong Yang, Ferrucci Luigi, Adam Martin, Boban, M., Wright, AF, Aulchenko, Y.S., Mariza de Andrade (31845), Holliday, E.G., Zaboli, G, Ding, Jingzhong, Albert V Smith, Bernhard Paulweber, Probst-Hensch Nicole M., Florian Ernst, Nick Hastie, Luigi Ferrucci (150038), Endlich Karlhans, Stumvoll, M. (Michael), Nicole M Probst-Hensch, Polasek, Ozren, Matthias Nauck, Stuart K. Kim (112150), De Andrade, M, Andrews, Jeanette S., van Duijn, Cornelia M., Anna Köttgen, Ciullo, M, Kao, WHL, Karlhans Endlich (112716), Garnaas Maija, Trompet, Stella, Palmer, Colin; id_orcid, Murgia, Federico, Struchalin, M., Gibson, G., Thor Aspelund, Ozren Polasek (3965693), Chen, M.H., Ching-Ti Liu, Pramstaller, PP, Hwang Shih-Jen, Rettig R., Vollenweider, P, Wilmar Igl, Oostra Ben A., Kovacs P, Afshin Parsa (175121), Coresh, J., Kutalik, Z. (Zoltán), Esko, T. (Tõnu), Fuchsberger, C., Pirastu, M, Cornelis, Marilyn C, Pistis, G, Chouraki, V. (Vincent), Tanaka, T, Haun M., Struchalin Maksim, Thun GA, Mägi, R., Mitchell, Braxton D., Demirkan, A, Köttgen, A., Colhoun H, Deshmukh, H., Liu Y., Launer, L. J., Garnaas M., Heid, I.M. (Iris), Andrade, M. de, Franke, A., Biffar, R., Chasman, D.I. (Daniel), Gyllensten Ulf, Campbell, Harry, Teumer, A. (Alexander), Goessling, W, Man Li (81239), Colin Palmer (165015), Liu, C. T., Ellinghaus, D., Wichmann H.-E., Wang JJ, Feitosa, M.F. (Mary Furlan), Jacqueline C. M. Witteman (175109), Bochud, M., Andrews, J. S., Bergmann, S, Tin Adrienne, O'Seaghdha C.M., Parsa, A., Goessling W, Döring Angela, Li G., Uitterlinden Andre G., Thun G.-A., Hu, Frank B., Portas, Laura, Gorski M, Chasman, DI, Georg Homuth (110202), Kardia, S.L.R., Kronenberg F, Holliday, E. G., Pistis, G. (Giorgio), Fox, C.S., Vilmundur Gudnason, Mitchell, Paul, Freedman Barry I., Doering, Angela, Ruggiero D., Wild S.H., Li, M., Ivana Kolcic, Chu, Audrey Yu-lei, Wilson, J.F., Imboden M, Goessling, W. (Wolfram), Raitakari, O., van Duijn CM, Wolfgang Koenig, Marie Metzger (156894), Chen M.-H., Launer Lenore J., Li M., Ding, J.Z., Schmidt, H., Mladen Boban, Ghazal Zaboli (174959), Ernst, F, Jacobs, Gunnar, Wichmann, HE, Isaacs, A., Kardia, Sharon L. R., Stracke, Sylvia, Trompet Stella, Stuart K Kim, Boban, Mladen, Koenig, W. (Wolfgang), Hwang, S.J., Wilson, James F; id_orcid, Nicole Glazer, Kim S.K., Feitosa M., Kovacs, P, Bergmann, S., Völker, U., Jukema J. Wouter, Rettig, R. (Rainer), Teumer, Alexander, Wright Alan F., Demirkan, A. (Ayşe), Ciullo Marina, Toshiko Tanaka (174638), Illig, T, Cavalieri M., Ming-Huei Chen, Bochud M., Aulchenko, Yurii S., Ute Nöthlings (140098), Toniolo Daniela, Nauck Matthias, Prokopenko, I, Giorgio Pistis, Böger CA, Struchalin, M, Schmidt, R. (Reinhold), Gian-Andri Thun, Kao WH, Hayward C, Colhoun Helen, Paul Mitchell (103717), Guo Li (174860), Cinzia Sala (74631), Siscovick D.S., Kardia, S.L., Gasparini, Paolo, Gudnason Vilmundur, Fox, Caroline, Giulianini F., Kovacs, Peter, Laura Portas (175069), Jacobs G, Parsa, A. (Afshin), Chen Ming-Huei, Reedik Mägi, Hayward, Caroline, Hofman, A. (Albert), Lehtimäki T, Viikari Jorma, Abbas Dehghan (174878), Albert Hofman, Igl, Wilmar, Daniel Taliun, Wild, S. H., Aspelund Thor, Ford, I., Nauck M., CARDIoGRAM Consortium, Kroemer, H.K., Hu Frank B., Heid I.M., Wheeler H.E., O'Seaghdha, Conall M, Coresh, J, Nick Hastie (175020), Tin, Adrienne, Mitchell, P, Schmidt, R., Helena Schmidt (174915), Aspelund, T, Deshmukh, Harshal, Elizabeth G Holliday, Wheeler HE, Oostra, B.A., Pirastu Mario, Stumvoll M, Turner, S.T., Völker U., Glazer N., Mitchell, P., Atkinson E.J., Chu A.Y., Paul Mitchell, Peter Kovacs (103720), Martin Adam (175082), Wilson, JF, Yang Q, Rossella Sorice, Alan R. Shuldiner (110828), Böger, Casten A, Tiit Nikopensius, Ernst Florian, Portas, L., Sorice, R, Taliun Daniel, Nikopensius T., Jukema J.W., Li, G., Metzger M., Cavalieri, M. (Margherita), Cinzia Sala, Zaboli G, Glazer Nicole, Pistis Giorgio, Kao, W. H. Linda, Wilson, J.F. (James), Murgia, F, Foster, M.C., Pattaro C., Wright A.F., Kardia, S.L.R. (Sharon), Andre Franke, Ellinghaus D, Braxton D Mitchell, Yurii S. Aulchenko (148330), Mitchell B.D., Peter Kovacs, Kaehoenen, Mika, Stracke S., Li, G (Guo), Rivadeneira Ramirez, F. (Fernando), Mario Pirastu (175088), Olden M, Ford, I. (Ian), Oostra B.A., Campbell, H. (Harry), Holliday EG, Wichmann, H.-E., Ciullo M, Lenore J. Launer (110269), Hu, F.B., Kao, W.H.L., Buckley, BM, WTCCC2, Gao, X, Thomas Illig (44906), Sala, C, Colhoun, Helen, Van Duijn, CM, Demirkan, A., Bochud, Murielle, Yang Q., Aspelund T, Eiriksdottir, G, Gasparini, P., Nikopensius Tiit, Wang, JJ, Uitterlinden, AG, Illig, T. (Thomas), Homuth G., Tamara B Harris, Deshmukh Harshal, Vitart Veronique, Madhumathi Rao, Chen MH, Haun, Margot, Hundertmark C., Carsten A Böger, Giulianini, F., Chu, Audrey Y, Aspelund, T. (Thor), Andrews Jeanette S., Madhumathi Rao (174925), Margherita Cavalieri (174919), Kronenberg F., Nauck, M., Cosetta Minelli, Campbell, Harry; id_orcid, Metzger Marie, Ferrucci, L. (Luigi), Sharon L R Kardia, Kolcic, I., Wheeler, HE, Kollerits, Barbara, Angela Döring (64291), de Andrade Mariza, Florian Ernst (174614), David Ellinghaus (87596), Liu CT, Ford, Ian, Conall M. O'Seaghdha (174855), Ford I., Colhoun H., Daniela Toniolo, Imboden M., Zemunik T., Shuldiner, A.R., Ingrid Borecki (175089), Kutalik Zoltan, Boerwinkle E., Paulweber Bernhard, Liu Y, Pattaro C, Wild Sarah H., Kovacs Peter, Province, M., Sorice R., Prokopenko, Inga, Hwang S.-J., Bergmann, Sven, Launer, Lenore J., Fox, C. S., Bergmann, S.M. (Sven), Wichmann, H. E., Giulianini Franco, Garnaas, M., Jacobs G., Imboden, M. (Medea), Franke Andre, Parsa A, Magi, Reedik, Liu, C.-T., Esko, T, David S. Siscovick (174822), Gierman Hinco J., David Ellinghaus, Brendan M. Buckley (175076), Buckley Brendan M., Lohman, K, Nikopensius, T, Aulchenko, Y. S., Boban, M, Maija Garnaas, Gunnar Jacobs (174977), Andre G. Uitterlinden (89938), Minelli C., Jukema, J.W., Schmidt, Helena, Ferrucci L., Luigi Ferrucci, Koenig, W, Stumvoll M., Probst-Hensch, N.M., Gyllensten U., Homuth, G., Mika Kähönen, H-Erich Wichmann, Meredith C Foster, Uitterlinden, A. G., Jacobs, Gunar, Andres Metspalu (61760), Sorice, Rossella, Fuchsberger, Christian, Goessling, Wolfram, Curhan Gary C., Coresh J, Haun M, Paolo Gasparini (139832), Laura Portas, Esko Tõnu, Rainer Rettig (112747), Endlich K., Freedman, B.I., Haun, M. (Margot), Polasek, O., Chu AY, Hinco J Gierman, Ayse Demirkan (174933), Endlich, Karlhans, Homuth, Georg, Harris, TB, Nöthlings Ute, Hundertmark, C., Zemunik, T. (Tatijana), Sorice, R., Franke, A. (Andre), O'Connell, J.R., Kollerits B, Jingzhong Ding (165392), Province Michael, Elizabeth J. Atkinson (174866), Li, Guo, Oostra, B.A. (Ben), Gao X, Kao W.H.L., Ruggiero Daniela, Parsa Afshin, Yongmei Liu, Antonietta Robino (149863), Vitart, V, Mitchell, B.D. (Braxton), Fuchsberger C, Raitakari O., Hayward, C, Pramstaller PP, Deshmukh H., Rossella Sorice (140754), Vilmundur Gudnason (8873), Borecki, I.B. (Ingrid), Gyllensten, U. (Ulf), Gorski, M, Eiriksdottir Gudny, Böger, CA, Audrey Y. Chu (174895), W. H. Linda Kao (160779), Helena Schmidt, Probst Hensch NM, Ding J., Igor Rudan, Wichmann, H. -Erich, Siscovick, D.S. (David), Paulweber, Bernhard, O'Seaghdha, C. M., Ferrucci, L., Foster Meredith C., Oostra, B. A., Palmer C., O'Seaghdha, C.M., Marie Metzger, Henry Völzke, Antonietta Robino, Esko T, Alex Doney (175054), Isaacs, A, Tönjes, A, Gudnason V., Lehtimäki, T, Helen Colhoun, Cornelis, Marilyn, Giulianini F, Thun Gian-Andri, Campbell, H, Claudia Hundertmark (174852), Hofman, Bert, Wright, A. F., Kutalik Z., Toniolo, D., Hwang SJ, Eiriksdottir G, Kolcic, I, Ferrucci, Luigi, Teumer A., Johnson A.D., Bernhard K Krämer, Olden, M., Olden, M, Hundertmark Claudia, Michael Stumvoll, Mägi R., Jorma Viikari, Witteman JC, Ulivi, Sheila, Kim, Stuart K., Heid, IM, Fuchsberger, C, Wichmann, H.-Erich, Heyo K Kroemer, Uitterlinden, André, Anke Tönjes, Krämer, Bernhard K., Tin A, Hundertmark, Claudia, Siscovick, DS, Struchalin, Maksim, Gao, X.Y., Kollerits, B. (Barbara), Holliday, EG, Gian-Andri Thun (142891), Sven Bergmann, Albert V. Smith (103644), Johansson Åsa, Stella Trompet, Murgia, F., Chen, M. H., Franco Giulianini, Lehtimaeki, Terho, Coresh, J. (Josef), Nothlings, Ute, Olden, M. (Matthias), Michael Province (175044), Demirkan Ayse, Wild, S.H., de Andrade, M., James F Wilson, Eiriksdottir, G., Eric Boerwinkle (36288), Federico Murgia (174898), Bernhard Paulweber (102633), Robino Antonietta, Johnson, AD, Alan F Wright, Metspalu A, Mitchell Paul, Catherine Helmer (175026), Wheeler, Heather E., Medea Imboden (110145), Gorski, M., Probst-Hensch, N. M., Caroline Hayward, Krämer B.K., Harris, Tamara B., Chouraki, Vincent, Trompet S, Giulianini, Franco, Harry Campbell, Ivana Kolcic (3212697), Frank B. Hu (127167), Launer, LJ (Lenore), Demirkan, Ayse, Schmidt, R, Uitterlinden, André; id_orcid, Schmidt, H, Ben A Oostra, Province, Michael, Veronique Vitart, Rivadeneira, F., Helmer, C, Hayward Caroline, Reiner Biffar (135695), Viikari, J, Rudan, Igor, Anna Köttgen (3111024), Mitchell Braxton D., Völzke H, Koenig Wolfgang, Martin Adam, Veronique Vitart (149854), Sylvia Stracke (175001), Turner S.T., Guo Li, Wilson, J. F., Dehghan, A. (Abbas), Smith, A. 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R., Ciullo M., Isaacs, Aaron; id_orcid, Andrews J.S., Duijn, C.M. van, Lohman Kurt, Shih-Jen Hwang (79945), Harris TB, Zemunik Tatijana, Franke, A, Bergmann S, Paul Ridker, Ruggiero, D, Gierman, HJ, Gyllensten, Ulf, Helmer C, Nikopensius T, Franke A, Bochud M, Fuchsberger C., Dehghan, Abbas, Atkinson, EJ, Cristian Pattaro, Minelli C, Caroline S Fox, Schmidt Helena, Pramstaller, P. P., Taliun D., O'Connell, J. R., Demirkan A., van Duijn C.M., James F. Wilson (150146), Böger, C. A., Bergmann S., Palmer Colin, Johnson AD, Wright, A.F. (Alan), Stephen T. Turner (103474), Ching-Ti Liu (100170), Mary Feitosa (165417), Vitart, V. (Veronique), Pistis G., Ridker Paul, Margot Haun, H.-Erich Wichmann (72009), Ian Ford (30666), Harry Campbell (30339), Boban Mladen, Freedman BI, Pirastu M., Ulivi, S., Raitakari, Olli, Krämer BK, Rudan Igor, Rudan, I., Jukema, J. W., Ulivi S., Franco Giulianini (175060), Wilson, James F., Sala, C. (Cinzia), Chu, Audrey Y., Hinco J. Gierman (174862), Ulf Gyllensten (13773), Siscovick, D. S., Stracke, S., Doney, A, Metzger M, Li, Man, Wang, J. J., Illig, Thomas, Tõnu Esko (102379), Döring, A. (Angela), Hu, Frank, Völker Uwe, Mary Feitosa, Igl, W, Chen, M.-H., Koenig W, Adam, M, Vitart V, O'Connell, Jeffrey R, Ketkar S., Imboden Medea, Cosetta Minelli (38846), Johnson, Andrew D., Reiner Biffar, Völzke H., Matthias Olden, Mariza de Andrade, Aulchenko, Y.S. (Yurii), Hwang, Shih-Jen, Jukema JW, Portas L., Hwang, SJ, Polasek, O. (Ozren), Lohman, Kurt, Ford Ian, Wellcome Trust Case Control Consortium 2, Gyllensten, U, Vitart V., Harshal Deshmukh (174893), Freedman B.I., Caroline S. Fox (110474), Yang, Q. (Qiong Fang), Alexander Teumer (112757), Holliday, Elizabeth G, Kao W. H. Linda, Marilyn C. Cornelis (174871), Boger, C.A., Kroemer, H.K. (Heyo), Parsa, Afshin, Kovacs P., Tõnu Esko, Liu Ching-Ti, Dehghan Abbas, Buckley B.M., Jukema, J. Wouter, Haun, M, Anke Tönjes (103703), Johnson, A.D., Afshin Parsa, Ernst F., Vollenweider, P., Völker U, Jeffrey R. O'Connell (170220) +999 morecore +2 more sourcesTIMP4 as a Potential Complementary Biomarker and Therapeutic Target in Membranous Nephropathy: A Multi-Omics Investigation with Clinical Validation
Journal of Inflammation ResearchQingsong Chen, Gang Wang, Ruo Zhao, Qiyuan Hu, Jiayun Li, Yuting Wang, Jingyang Ran, Qi Huang, Guiquan Yu, Yanjia Luo, Xiaohui Liao Department of Nephrology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ...Chen Q, Wang G, Zhao R, Hu Q, Li J, Wang Y, Ran J, Huang Q, Yu G, Luo Y, Liao X +10 moredoaj Comprehensive Evidence for Mortality and Underlying Morbidity Related to Visceral Fat Distribution
Med ResearchLinking obesity to mortality is an intriguing and controversial topic. This study tried to comprehensively assess 8 adiposity surrogates and mortality association among middle‐to‐old‐aged adults to identify a superior one, and explore explanatory ...Haolong Zhou, Danyang Ling, Qin Huang, Jiaojun Liang, Guanhua Su, Zhangbo Cui, Ziwei Chen, Xiaowen Ma, Zhou Jiang, Shuo Zheng, Haodong Tian, Qi Wang +11 moredoaj +1 more sourceDifferential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales +11 morewiley +1 more sourceGenome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1. [PDF]
, 2011 Hypovolemic shock (dengue shock syndrome (DSS)) is the most common life-threatening complication of dengue. We conducted a genome-wide association study of 2,008 pediatric cases treated for DSS and 2,018 controls from Vietnam.Simmons, C, Tuan, NM, Long, H.T., Sarah J Dunstan, Gan, Tran Thi, Martin L Hibberd, Chau, T.N.B., Long, Hoang Truong, Van N Vinh Chau, Nguyen, Khor, C.C., Tuan, Nguyen Minh, Hieu, Nguyen Trong, Hong, Rick T. H., Wills, Bridget, Lanh, M.N., Tan, Dennis EK, Thuy, Tran Thi, Tham, NTH, Farrar, Jeremy, Gan, TT, Dunstan, Sarah, Dunstan, SJ, Pang, J., Teo, Y-Y, Nguyen Minh Tuan, Lien, LB, Tuan, N.M., Tran Thi Thuy, Davila, Sonia, Pang, J, Lanh, MN, Long, HT, Hoang Truong Long, Thuy, T.T., Sonia Davila, Binh, Nguyen Thi Nguyet, Simmons, Cameron P, Davila, S, Nguyen Trong Hieu, Tan, DEK, Ong, R.T.H., Tham, Nguyen Thi Hong, Le Bich Lien, Hibberd, ML, Sakuntabhai, A, Chau, TN, Gan, T.T., Mai Ngoc Lanh, Van Tram, T, Anavaj Sakuntabhai, Dennis E K Tan, Teo, Yik-Ying, Binh, NTN, Nguyet, N.M., Tan, Dennis E. K., Hibberd, Martin L, Dunstan, Sarah J, Ong, RT, Chau, Tran Nguyen Bich, Simmons, Cameron, Rick T H Ong, Teo, YY, Wills, B, Van N Vinh Chau, N, Wills, B., Simmons, Cameron P., Lien, L.B., Ta Van Tram, Tan, D.E.K., Chiea Chuen Khor, Pang, Junxiong, Ong, RTH, Nguyen Thi Nguyet Binh, Dunstan, S, Nguyen Minh Nguyet, Farrar, J, Nguyet, NM, van Vinh Chau, Nguyen, Jeremy Farrar, Khor, CC, Simmons, C.P., Nguyen Thi Hong Tham, Tri, Le Trung, Hibberd, M.L., Van Tram, Ta, Le Trung Tri, Tan, DE, Simmons, CP, Tran Thi Gan, Sakuntabhai, A., Nguyet, Nguyen Minh, Van N Vinh Chau, N., Nguyen Van N Vinh Chau, Lanh, Mai Ngoc, Farrar, J., Hibberd, Martin, L., Binh, N.T.N., Junxiong Pang, Sakuntabhai, Anavaj, Khor, Chiea Chuen, Tri, L.T., Van Tram, T., Thuy, TT, Binh, NT, Ong, Rick TH, Tran Nguyen Bich Chau, Bridget Wills, Yik-Ying Teo, Hieu, NT, Davila, S., Cameron P Simmons, Lien, Le Bich, Tri, LT, Chau, TNB, Hibberd, Martin,, Tham, N.T.H., Hieu, N.T., Tham, NT, Dunstan, S.J., Teo, Y.-Y. +119 morecore +1 more source
