Results 101 to 110 of about 43,083,361 (310)
Not so benign
eLife, 2018 Susceptibility to uterine fibroids, benign tumors that affect the health of many women, is linked to genes that are responsible for preserving genome integrity and promoting genitourinary development.Barbara Riveradoaj +1 more sourceTranslophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura +11 morewiley +1 more sourceGenome-Wide Association Study of Vascular Dementia [PDF]
Stroke, 2012 Background and Purpose— Most studies investigating the genetics of dementia have focused on Alzheimer disease, but little is known about the genetics of vascular dementia. The aim of our study was to identify new loci associated with vascular dementia. Methods— We performed a genome-Schrijvers, Elisabeth M.C., Schürmann, Britta, Koudstaal, Peter J., Van Den Bussche, Hendrik, Van Duijn, Cornelia M., Hentschel, Frank, Heun, Reinhard, Hofman, Albert, Jessen, Frank, Kölsch, Heike, Kornhuber, Johannes, Peters, Oliver, Rivadeneira, Fernando, Rüther, Eckart, Uitterlinden, André G., Riedel-Heller, Steffi, Dichgans, Martin, Wiltfang, Jens, Maier, Wolfgang, Breteler, Monique M.B., Ikram, M. Arfan +20 moreopenaire +5 more sourcesGenome-Wide Association Studies and Beyond [PDF]
Annual Review of Public Health, 2010 Genome-wide association studies (GWAS) provide an important avenue for undertaking an agnostic evaluation of the association between common genetic variants and risk of disease. Recent advances in our understanding of human genetic variation and the technology to measure such variation have made GWAS feasible.openaire +2 more sourcesMeta-Analysis in Genome-Wide Association Studies [PDF]
Pharmacogenomics, 2009 The advent of genome-wide association studies has allowed considerable progress in the identification and robust replication of common gene variants that confer susceptibility to common diseases and other phenotypes of interest. These genetic effect sizes are almost invariably moderate to small in magnitude and single studies, even if large, are ...Zeggini, E., Ioannidis, J. P.openaire +3 more sourcesNo evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index:results from meta-analyses of 80,607 subjects [PDF]
, 2014 Plasma fibrinogen is an acute phase protein playing an important role in the blood coagulation cascade having strong associations with smoking, alcohol consumption and body mass index (BMI).Seedorf, Udo, Maat, Moniek P. M. de, Trompet, S., Ridker, P.M., Caroline Hayward (149856), Sanna, Serena, Boerwinkle, E., Fornage, Myriam, Huffman, J.E. (Jennifer), Biffar Reiner, Strawbridge, RJ, Bandinelli, S, Dongen, J. van, Rudnicka, AR, Toshiko Tanaka, Peters, Annette, Sanna, S., Marco Masala, Rose, LM, John M Starr, Huffman, JE, Rudnicka, Alicja R., Cucca, F. (Francesco), Baumert, J. (Jens), Reiner, A.P., McKnight B, McArdle WL, Maria Sabater-Lleal, Navarro, Pau, Uitterlinden, André G, Anders Mälarstig, Sabater-Lleal Maria, Stella Trompet (174901), Huffman JE, Morange Pierre-Emmanuel, Trompet, S. (Stella), Mälarstig, A, Grotevendt Anne, Hugh Watkins, Chu, A.Y., Franco, O.H., Alexander P. Reiner (178706), Willemsen, G.A.H.M. (Gonneke), O'Donnell, CJ, Deary, Ian J, Kavousi, M, Ridker PM, Rose, Lynda M, Hofman, A., Sarah H. Wild (130180), Melanie Waldenberger, Starr John M., Basu, S. (Saonli), Kenneth J Mukamal, J. Wouter Jukema (127361), Franzosi, Maria Grazia, Rose, L.M. (Lynda), Kavousi Maryam, Mukamal KJ, de Geus, Eco J C, Sattar, N, Aarno Palotie (41342), Rivadeneira, F, Wilson JF, Naitza Silvia, Strachan, David P., Henry Völzke (64286), Oudot-Mellakh, T, Lumley, T., Rumley, Ann, Anders Mälarstig (3900385), Baumert, J., Naveed Sattar, Hofman Albert, Starr, J.M. (John), Abbas Dehghan, Lopez, L.M., Westendorp RG, de Geus, EJ, Slagboom, PE, Schlessinger, D. (David), Morange, Pierre-Emmanuel, Illig T, Biffar, R, Thomas Illig, Rückerl, Regina, Homuth, G. (Georg), Völzke, H. (Henry), Kolcic, I. (Ivana), Huffman, Jennifer E, Homuth G, Chasman, Daniel I., van Dongen, J.; id_orcid, Baumert Jens, Fernando Rivadeneira, Rückerl, R, Strawbridge, R.J., Chu, AY, Franco, Oscar H, Silveira, Angela, de Craen, Anton J M, Franzosi, MG, Daniel I Chasman, Wild, S.H. (Sarah), Silvia Naitza, Steri, M, Geus, Eco J. C. de, Seedorf, U, Buckley, B.M., Tang Weihong, Smith N.L., Dehghan A, de Craen, A.J., Illig, T., Morange, P.-E. (P.), Barbara McKnight, Johan Eriksson (131534), Lorna M. Lopez (107685), Christopher J. O'Donnell (183188), Stefania Bandinelli (150002), Franzosi, M., Annette Peters, Rudi G J Westendorp, Kolcic Ivana, Wilson, James F, Maristella Steri (186157), van Dongen, J, O'Donnell, C.J. (Christopher), Ian J Deary, Folsom, Aaron R, Völzke, H, Jaejoon Song (680719), Sanna Serena, Witteman, Jacqueline C.M., Dehghan, Abbas, Stott, D.J. (David. J.), Slagboom, P.E., Hofman A, Wallaschofski, Henri, de Geus, EJC, Ferrucci Luigi, Hottenga, JJ (Jouke Jan), Stott David J., Reiner AP, Hottenga, J.J., James F. Wilson (150146), Chu, A.Y. (Audrey), Stott, D.J., Huang, J., Mukamal, K.J., Luigi Ferrucci (150038), Mukamal, K. (Kenneth), Polasek, Ozren, Anne Grotevendt (680720), Clarke R, Eco J C de Geus, McArdle, W.L. (Wendy), Martina Müller-Nurasyid, Müller-Nurasyid, M., Robert Clarke (17961), Trompet, Stella, Wild, Sarah H, Ian Ford (30666), Harry Campbell (30339), Mälarstig, Anders, Sabater-Lleal, M., Waldenberger, M., Morange PE, Van Dongen, J. (Jenny), Joshua C Bis, Lumley, Thomas, Wilson, James F., Chu, Audrey Y., Smith, Nicholas L., Cucca, Francesco, Myriam Fornage, Ozren Polasek (3965693), Maria Sabater-Lleal (396331), Chen, M.H., Schlessinger, David, Illig, Thomas, Jenny van Dongen (109719), Seedorf, U. (Udo), Voezke, Henry, Rückerl, R. (Regina), de Craen, Anton J. M., Masala M, Navarro, P. (Pau), Sabater-Lleal, Maria, Marco Masala (274614), Koenig W, Widen, E. (Elisabeth), Elisabeth Widen, Alexander P Reiner, Trégouët, David-Alexandre, Masala, M, Reiner Biffar, Tanaka, T, Oscar H Franco, Franco, O.H. (Oscar), John M. Starr (107707), Jukema JW, Franco OH, Tofler, Geoffrey H., Polasek, O. (Ozren), Ford Ian, Smith, N.L., Taylor K, Ridker Paul M., Westendorp, RGJ, Mälarstig A, Mukamal, Kenneth J., O'Donnell Christopher J., Basu, Saonli, Alexander Teumer (112757), Rudnicka AR, Palotie Aarno, Strachan David P., Anders Hamsten (62728), Watkins H, Smith, N.L. (Nicholas L.), David-Alexandre Trégouët, Bis, Joshua C, Franzosi Maria Grazia, Serena Sanna, Tofler, G.H. (Geoffrey), Räikkönen, K. (Katri), Tiphaine Oudot-Mellakh, Wendy L. McArdle (110155), Bis, J.C. (Joshua), Biffar, R., Alicja R. Rudnicka (168859), Chasman, D.I. (Daniel), Stott, David J, Campbell, Harry, Fornage Myriam, Teumer, A. (Alexander), Rudnicka Alicja R., Dehghan Abbas, Folsom, Aaron R., Jukema, J. Wouter, Naitza, Silvia, Song, J, Sattar Naveed, Wilson James F., Koenig, W., Maryam Kavousi (524142), Davies, G, Francesco Cucca, Wallaschofski, H. (Henri), Dorret I Boomsma, Gonneke Willemsen (75573), Räikkönen, K, Biffar R, Jacqueline C. M. Witteman (175109), Steri Maristella, Morange, PE, Ozren Polasek, J Wouter Jukema, Basu Saonli, Palotie, Aarno, Stott, David J., Bis JC, Franco, Oscar H., Dorret I. Boomsma (109746), Rivadeneira Fernando, Hottenga, J.J. (Jouke Jan), Starr, J.M., Martina Müller-Nurasyid (193464), Paul M Ridker, Peters A, Liu, K.Y., Trégouët DA, Craen, A.J. (Anton) de, Folsom AR, Melanie Waldenberger (236985), Chasman, DI, Georg Homuth (110202), Bis Joshua C., Jennifer E Huffman, Hottenga Jouke-Jan, Boomsma Dorret I., McKnight, B, Eriksson, J., Jens Baumert, Lahti, Jari, Ivana Kolcic, Jaejoon Song, Bis, J.C., Wilson, J.F., Naitza, S. (Silvia), Lynda M Rose, Buckley BM, Lorna M Lopez, Kent Taylor (103741), Wolfgang Koenig, Siscovick David S., Maelarstig, Anders, Deary, IJ, Fornage M, Seedorf, U., Widen, Elisabeth, Jukema, J.W. (Jan Wouter), Campbell, H., Grotevendt, A. (Anne), Fornage, M., Weihong Tang (178672), Trompet Stella, Tiphaine Oudot-Mellakh (161558), Watkins, H. (Hugh), Koenig, W. (Wolfgang), Kenneth J. Mukamal (301147), Wilson, James F; id_orcid, Westendorp, R.G.J., Hottenga JJ, Tregouet, D.-A. (David-Alexandre), McArdle Wendy L., Bis, Joshua C., Jukema J. Wouter, Tanaka, T. (Toshiko), Huang, Jie, Navarro P, Thomas Lumley, Teumer, Alexander, Bengt Sennblad, de Maat, Moniek P M, Anuj Goel (258576), Deary, I.J., David Schlessinger, Toshiko Tanaka (174638), Illig, T, Bandinelli, S. (Stefania), Hottenga, JJ, Siscovick, David S., Pau Navarro, Ming-Huei Chen, Clarke, R. (Robert), Lahti, J, Palotie A, Saonli Basu (28868), Willemsen, G.; id_orcid, Deary IJ, Henri Wallaschofski, Lowe Gordon D., Navarro, P., Eriksson, J. (Johan), Hayward C, Masala, G. (Giovanna), Baumert, J, Gail Davies (107670), Raeikkonen, Katri, Rose, L.M., Hamsten Anders, Boomsma, Dorret I., McArdle, W.L., Morange, P.E., Chen Ming-Huei, Davies G, Basu, S., Boerwinkle Eric, Hayward, Caroline, Hofman, A. (Albert), David Schlessinger (2399), Abbas Dehghan (174878), Albert Hofman, Maat, M.P.M. (Moniek) de, Fornage, M, Sattar N, Uitterlinden André G., Ford, I., Silveira Angela, Grotevendt, A, Lahti Jari, Siscovick, David S, Geus, E.J.C. (Eco) de, Aarno Palotie, Homuth Georg, Boomsma DI, Rudnicka, A.R. (Alicja), Maristella Steri, Müller-Nurasyid, Martina, Strawbridge Rona J., Deary Ian J., Palotie, A. (Aarno), Cucca, F, Katri Räikkönen, Liu, Kiang, Grotevendt A, Stott, DJ, Buckley, B.M. (Brendan M.), Naitza, S., Alexander Teumer, Sennblad, B., Weihong Tang, Mälarstig, A., Boerwinkle E, Watkins, Hugh, Chen, M.-H. (Ming-Huei), Bandinelli Stefania, de Maat, Moniek P. M., Hayward, C. (Caroline), Joshua C. Bis (183182), Slagboom, PE (Eline), Tang, W., Hottenga, Jouke-Jan, Taylor, K.D. (Kent), Franzosi, M.G., Reiner Alexander P., Oscar H. Franco (303354), Wallaschofski H, Angela Silveira (162071), Craen, Anton J. M. de, Seedorf U, Wilson, JF, Hamsten A, Audrey Y Chu, Müller-Nurasyid Martina, Goel, A. (Anuj), Polasek O, Wild, Sarah H., Trégouët, D.A., de Geus, Eco J. C., Rumley, A. (Ann), Sanna, S. (Serena), Widen, E, Sabater-Lleal, M, Hugh Watkins (62729), Robert Clarke, Tofler GH, Lowe GD, Chasman, D.I., Goel Anuj, Bandinelli S, Schlessinger D, Campbell Harry, Lopez, L.M. (Lorna M.), Tang, WH, Lowe, GD, Oudot Mellakh T, Kiang Liu (113645), Rudnicka, Alicja R, Rumley Ann, Biffar, Reiner, Ridker, Paul M., Taylor, K, Silvia Naitza (186150), Thomas Lumley (57337), Taylor Kent, Uitterlinden AG, Huang Jie, Räikkönen, Katri, Boerwinkle, E. (Eric), Witteman, JC, Reiner, AP, Rivadeneira Ramirez, F. (Fernando), Baumert J, McKnight, Barbara, Schlessinger David, Ford, I. (Ian), Folsom, AR, Oudot-Mellakh, T., Rudi G. J. Westendorp (188393), Campbell, H. (Harry), Chu Audrey Y., Völzke Henry, Sanna, S, Taylor, K., Kavousi, M., de Geus EJ, Liu Kiang, Illig Thomas, Peters Annette, Huffman, Jennifer E., Myriam Fornage (45591), Elisabeth Widen (75580), Mukamal, Kenneth J, Buckley, BM, Goel, A, Maria Grazia Franzosi, Franco Duran, OH, Thomas Illig (44906), Wallaschofski, H, Ford, I, Müller-Nurasyid, M. (Martina), Wallaschofski, H., Widen, E., Pierre-Emmanuel Morange (161602), Boerwinkle, Eric, Rueckerl, Regina, Navarro, P, Jens Baumert (39941), Paul M. Ridker (191917), Boerwinkle, E, Uitterlinden, AG, Illig, T. (Thomas), Wild, SH, David P Strachan, Tofler Geoffrey H., Bis, JC, Bandinelli, S., Folsom, A.R. (Aaron), de Maat, M.P.M., Pierre-Emmanuel Morange, Rivadeneira F, Eriksson, Johan, Jie Huang (104235), Liu, K, Chen MH, Rose LM, Chu, Audrey Y, Jukema, JW, Goel, Anuj, Watkins, H., David J. Stott (280323), Jari Lahti, Schlessinger, D., Lopez, Lorna M., Slagboom PE, Udo Seedorf (18766), Starr, John M., Palotie, A, Ian Ford, Homuth, G, Ann Rumley, Smith Nicholas L., Serena Sanna (145737), Mukamal, KJ, Campbell, Harry; id_orcid, Lahti, J. (Jari), Westendorp Rudi G. J., Francesco Cucca (145742), Maryam Kavousi, Taylor, Kent, Ferrucci, L. (Luigi), Chasman, Daniel I, Jennifer E. Huffman (220403), Kolcic, I., Widen Elisabeth, Folsom Aaron R., Eriksson, J, Anton J M de Craen, Mälarstig Anders, de Craen, AJM, Huang, J. (Jian), Ford, Ian, Eriksson J, McKnight, B., Witteman, Jacqueline C M, Steri, M. (Maristella), Steri, M., Liu K, Lumley T, Franzosi MG, Franco Oscar H., Huffman Jennifer E., Strawbridge, Rona J., Palotie, A., McKnight Barbara, Baumert, Jens, Tofler, Geoffrey H, van Dongen Jenny, Basu S, Sennblad B, Bengt Sennblad (43745), Wild Sarah H., Silveira A, Bandinelli, Stefania, O'Donnell CJ, Christopher J O'Donnell, de Maat, MP, Jacqueline C M Witteman, McKnight, B. (Barbara), Huang, J, Brendan M Buckley, Pau Navarro (160568), Franco, OH, Folsom, A.R., Cucca, F., Sennblad Bengt, David S. Siscovick (174822), Chen, Ming-Huei, Chen, MH, Navarro Pau, Chasman DI, Rumley, A., Goel, A., Tang, Weihong, Henri Wallaschofski (112750), David S Siscovick, Jari Lahti (149903), P. Eline Slagboom (28184), Udo Seedorf, Eriksson Johan, Räikkönen Katri, Lowe, G.D., Brendan M. Buckley (175076), Buckley Brendan M., Lynda M. Rose (225264), Trégouët David-Alexandre, Waldenberger, Melanie, Johan Eriksson, Naitza, S, Ferrucci, L, Uitterlinden, A.G. (André), Lahti, J., McArdle, Wendy L., Anders Hamsten, Ridker, PM, Jukema, J.W., Luigi Ferrucci, Koenig, W, Lowe, Gordon D, Aaron R Folsom, Waldenberger, M. (Melanie), Anuj Goel, Davies, Gail, Homuth, G., Buckley, Brendan M., Lopez Lorna M., Dehghan, A., Koenig, Wolfgang, Teumer, A., Rumley A, Masala, M., Sennblad, B, Oudot-Mellakh Tiphaine, Rose, Lynda M., Müller-Nurasyid, M, Gordon D Lowe, Teumer, A, Sennblad, B. (Bengt), Westendorp, Rudi G. J., Kavousi, M. (Maryam), Polasek, O., Chu AY, Wild, Sarah H; id_orcid, Regina Rückerl (72005), Nicholas L. Smith (354787), Homuth, Georg, Witteman Jacqueline C. M., de Maat Moniek P. M., Starr, JM, Annette Peters (62601), Lopez, Lorna M, André G. Uitterlinden (2213413), Wild SH, Angela Silveira, Hofman, Albert, Grotevendt, Anne, Deary, Ian J., Eric Boerwinkle, Teumer Alexander, Chasman Daniel I., Davies Gail, Aaron R. Folsom (178702), Tang, W, Basu, S, Hayward, C, de Craen AJ, Rückerl, R., Hamsten, A, Geus, E.J.C. de, Strachan, D.P. (David), Rona J Strawbridge, Wolfgang Koenig (26222), Strachan, DP, Jouke-Jan Hottenga (75574), Lumley Thomas, Audrey Y. Chu (174895), Stefania Bandinelli, Wallaschofski Henri, Rumley, A, Buckley, Brendan M, Davies, G. (Gail), Siscovick, D.S. (David), Daniel I. Chasman (120866), Waldenberger, M, Ferrucci, L., Gail Davies, de Geus Eco J. C., Jouke-Jan Hottenga, Regina Rückerl, Slagboom, P.E. (Eline), Henry Völzke, Geoffrey H. Tofler (680721), Tanaka, T., Liu, K., Müller Nurasyid M, Lopez LM, Peters, A. (Annette), Witteman, Jacqueline C. M., Tofler, GH, Strachan, David P, Grotevendt, A., Song Jaejoon, Tanaka Toshiko, Ian J. Deary (107724), Mueller-Nurasyid, Martina, Hayward, C., Jenny van Dongen, Dongen, Jenny van, Waldenberger M, Campbell, H, Rudnicka, A.R., de Maat, Moniek; id_orcid, Strawbridge, Rona J, Alicja R Rudnicka, Hofman, Bert, Jukema, J Wouter, Watkins, H, Kolcic, I, Oudot-Mellakh, Tiphaine, Widen E, Nicholas L Smith, Naveed Sattar (8785), Lowe, G.D.O. (Gordon), Ferrucci, Luigi, Dehghan, A, Boomsma, D.I. (Dorret), Sattar, Naveed, Lumley, T, Silveira, A., Ming-Huei Chen (73691), Witteman JC, Moniek P M de Maat, Hamsten, A., Westendorp, Rudi G J, Rose Lynda M., Sanna S, Stott DJ, Siscovick, DS, Slagboom, P. Eline, Davies, G., David J Stott, Ridker, Paul M, Rivadeneira, Fernando, Lahti J, Waldenberger Melanie, O'Donnell, Christopher J., Willemsen G, Willemsen, Gonneke, Stella Trompet, de Craen, AJ, Clarke, Robert, Tang, W. (Weihong), Kent Taylor, Gordon D. Lowe (372011), Davies, G.E., Katri Räikkönen (149957), de Geus, E.J.C.; id_orcid, Saonli Basu, Völzke, Henry, Tregoueet, David-Alexandre, Peters, A., Wild, S.H., Clarke, R., Gonneke Willemsen, Sabater Lleal M, Hamsten, A. (Anders), James F Wilson, Eric Boerwinkle (36288), Meyre, David, Anne Grotevendt, Geoffrey H Tofler, Slagboom P. Eline, Steri M, Willemsen, G, Caroline Hayward, Boomsma, D.I.; id_orcid, Wilson, J.F. (James F), Westendorp, R.G.J. (Rudi), de Maat MP, Navarro, Pau; id_orcid, Trompet S, Boomsma, Dorret I, Tofler, G.H., Harry Campbell, Rückerl R, Siscovick DS, Sabater-Lleal, M. (Maria), Song, J., van Dongen, Jenny, Ivana Kolcic (3212697), Strachan, D.P., Smith, Nicholas L, Jie Huang, Uitterlinden, André; id_orcid, Maria Grazia Franzosi (62722), P Eline Slagboom, Rivadeneira, F., Hayward Caroline, De Maat, De, Reiner Biffar (135695), Sattar, N. (Naveed), Craen, A.J.M. de, Huffman, J.E., Kavousi M, Völzke H, Koenig Wolfgang, Seedorf Udo, Rückerl Regina, Clarke, R, O'Donnell, C.J., Dehghan, A. (Abbas), Völzke, H., Eco J. C. de Geus (109745), Fornage, M. (Myriam), Lopez, LM, Räikkönen K, O'Donnell, Christopher J, Sattar, N., Masala, Marco, Strawbridge, R.J. (Rona), van Dongen J, André G Uitterlinden, David-Alexandre Trégouët (133741), Ann Rumley (90044), Willemsen Gonneke, Tanaka T, Song, Jaejoon, Mälarstig, A. (Anders), Siscovick, D.S., Tang W, Reiner, A. (Alexander), Rona J. Strawbridge (419006), Goel A, Slagboom, P Eline, Boomsma, DI, Moniek P. M. de Maat (316792), McArdle, Wendy L, Starr JM, Reiner, Alexander P, Uitterlinden, A.G., Naitza S, Teumer A, Sarah H Wild, Silveira, A, Biffar, R. (Reiner), Ford I, Masala Marco, Ridker, P.M. (Paul), Huang J, Kolcic I, Peters, A, McArdle, WL, Polasek Ozren, Starr, John M, Sennblad, Bengt, Ferrucci L, David P. Strachan (110302), Westendorp, RG, Räikkönen, K., Strawbridge RJ, Willemsen, G., Georg Homuth, Tanaka, Toshiko, Kolcic, Ivana, Trégouët, DA, Schlessinger, D, Smith, NL, de Craen Anton J. M., Boomsma, D.I., Hofman, A, Lumley, T. (Thomas), Barbara McKnight (103714), Tang, W.H., Albert Hofman (107303), Trompet, S, Silveira, A. (Angela), Anton J. M. de Craen (188398), Witteman, J.C.M. (Jacqueline), Song, J. (Jaejoon), Cucca Francesco, Kiang Liu, Witteman, J.C.M., Hayward, Caroline; id_orcid, Clarke Robert, Kavousi, Maryam, Strachan DP, Lowe, Gordon D., Oudot-Mellakh, T. (Tiphaine), Polasek, O, Wendy L McArdle, Song J, Deary, I.J. (Ian J.), Campbell H, Steri, Maristella, Mukamal Kenneth J., Watkins Hugh, Hamsten, Anders, Fernando Rivadeneira (61551), Reiner, Alexander P., Maat, M.P.M. de, O'Donnell, Christopher J., Rueckerl Regina, Deary Ian J, Uitterlinden, Andre G., Strachan David P, Siscovick David S, Boomsma Dorret I, Jukema J Wouter, Chu Audrey Y, Stott David J, Lopez Lorna M, Franco Oscar H, Starr John M, Buckley Brendan M, Smith Nicholas L, Huffman Jennifer E, MuellerNurasyid Martina, McArdle Wendy L, Raeikkonen Katri, Ridker Paul M, OudotMellakh Tiphaine, de Maat Moniek P M, Rudnicka Alicja R, Witteman Jacqueline C M, de Craen Anton J M, Wilson James F, Maelarstig Anders, Rose Lynda M, Slagboom P Eline, Chen MingHuei, Voezke Henry, de Geus Eco J C, SabaterLleal Maria, Hottenga JoukeJan, Mukamal Kenneth J, Chasman Daniel I, Tregoueet DavidAlexandre, Wild Sarah H, Bis Joshua C, Uitterlinden Andre G, Tofler Geoffrey H, Lowe Gordon D, O'Donnell Christopher J, Westendorp Rudi G J, Strawbridge Rona J, Morange PierreEmmanuel, Reiner Alexander P, Folsom Aaron R +940 morecore +1 more sourceThe Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen +6 morewiley +1 more source
