Results 1 to 10 of about 851,678 (251)
Cells, 2022 Several genes associated with periodontitis have been identified through genome-wide association studies (GWAS); however, known genes only explain a minority of the estimated heritability.
Guirong Zhu +4 more
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Identification of Druggable Genes for Asthma by Integrated Genomic Network Analysis
Biomedicines, 2022 Asthma is a common and heterogeneous disease characterized by chronic airway inflammation. Currently, the two main types of asthma medicines are inhaled corticosteroids and long-acting β2-adrenoceptor agonists (LABAs).
Wirawan Adikusuma +7 more
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Replication of the Association of the 6q22.31c Locus near with Pulse Rate in the Korean Population [PDF]
Genomics & Informatics, 2012 Pulse rate is known to be related to diverse phenotypes, such as cardiovascular diseases, lifespan, arrhythmia, hypertension, lipids, diabetes, and menopause. We have reported two genomewide significant genetic loci responsible for the variation in pulse
Nam Hee Kim +3 more
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The genetics of obesity: A narrative review [PDF]
Precision and Future Medicine, 2022 Monogenic obesity is a rare, early-onset, and severe form of obesity that has a Mendelian inheritance pattern, high penetrance, and large genetic effect. In contrast, common polygenic obesity is more prevalent and has pattern of heritability derived from
Young Bae Sohn
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How data science and AI-based technologies impact genomics
Singapore Medical Journal, 2023 Advancements in high-throughput sequencing have yielded vast amounts of genomic data, which are studied using genome-wide association study (GWAS)/phenome-wide association study (PheWAS) methods to identify associations between the genotype and phenotype.
Jing Lin, Kee Yuan Ngiam
doaj +1 more source
Frontiers in Plant Science, 2023 IntroductionMycosphaerella leaf disease (MLD) is one of the most prevalent foliar diseases of Eucalyptus globulus plantations around the world. Since resistance management strategies have not been effective in commercial plantations, breeding to develop ...
Marianella Quezada +5 more
doaj +1 more source
Genome-Wide Association Study on Longitudinal Change in Fasting Plasma Glucose in Korean Population [PDF]
Diabetes & Metabolism Journal, 2023 Background Genome-wide association studies (GWAS) on type 2 diabetes mellitus (T2DM) have identified more than 400 distinct genetic loci associated with diabetes and nearly 120 loci for fasting plasma glucose (FPG) and fasting insulin level to date ...
Heejin Jin +6 more
doaj +1 more source
Genome-wide association study of male sexual orientation [PDF]
, 2017 Family and twin studies suggest that genes play a role in male sexual orientation. We conducted a genome-wide association study (GWAS) of male sexual orientation on a primarily European ancestry sample of 1,077 homosexual men and 1,231 heterosexual men ...
Cloninger, C. Robert +2 more
core +5 more sources
Dissecting the genetic heterogeneity of gastric cancerResearch in context
EBioMedicine, 2023 Summary: Background: Gastric cancer (GC) is clinically heterogenous according to location (cardia/non-cardia) and histopathology (diffuse/intestinal). We aimed to characterize the genetic risk architecture of GC according to its subtypes.
Timo Hess +133 more
doaj +1 more source
Meta-Analysis of Genome-Wide Linkage Studies in Celiac Disease. [PDF]
, 2009 OBJECTIVE: A meta-analysis of genome-wide linkage studies allows us to summarize the extensive information available from family-based studies, as the field moves into genome-wide association studies. METHODS: Here we apply the genome scan meta-analysis
Babron MC +9 more
core +1 more source