Results 21 to 30 of about 1,303,219 (221)

Genome- and Transcriptome-wide Association Studies to Discover Candidate Genes for Diverse Root Phenotypes in Cultivated Rice

open access: yesRice, 2023
Root system architecture plays a crucial role in nutrient and water absorption during rice production. Genetic improvement of the rice root system requires elucidating its genetic control.
Shujun Wei   +7 more
doaj   +1 more source

Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes

open access: yesHuman Genomics, 2019
Background While genome-wide association studies (GWAS) of multiple myeloma (MM) have identified variants at 23 regions influencing risk, the genes underlying these associations are largely unknown. To identify candidate causal genes at these regions and
Molly Went   +28 more
doaj   +1 more source

Genome-wide association studies in Plasmodiumspecies [PDF]

open access: yesBMC Biology, 2010
Abstract Genome-wide association studies (GWAS) look for correlations between traits of interest and genetic markers spread throughout the genome. A recent study in BMC Genetics has found that populations of the malaria parasite Plasmodium vivax should be amenable to GWAS searching for a genetic basis of parasite pathogenicity.
Penman, Bridget   +3 more
openaire   +6 more sources

Genome-Wide Association Study of Motor Coordination [PDF]

open access: yesFrontiers in Human Neuroscience, 2021
The ability to finely control our movement is key to achieving many of the educational milestones and life-skills we develop throughout our lives. Despite the centrality of coordination to early development, there is a vast gap in our understanding of the underlying biology.
Mountford, HS   +3 more
openaire   +7 more sources

Developing Novel Therapeutic Strategies Against Ring Finger Protein 213 Vasculopathy: Is It an Achievable Goal?

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
See Article Choi et ...
Minghua Liu, Jose Gutierrez
doaj   +1 more source

Guidelines for Genome-Wide Association Studies

open access: yesPLoS Genetics, 2012
Genome-wide association studies (GWAS) have revolutionized human genetics. They have led to the identification of thousands of loci that affect both normal variation and susceptibility to disease, and have clarified our understanding of the genetic architecture of complex traits.
Scott M. Williams   +3 more
openaire   +5 more sources

Genome-wide association study of Tourette's syndrome [PDF]

open access: yesMolecular Psychiatry, 2012
Tourette's syndrome (TS) is a developmental disorder that has one of the highest familial recurrence rates among neuropsychiatric diseases with complex inheritance. However, the identification of definitive TS susceptibility genes remains elusive. Here, we report the first genome-wide association study (GWAS) of TS in 1285 cases and 4964 ancestry ...
Barbara Kremeyer   +114 more
openaire   +9 more sources

Selecting Closely-Linked SNPs Based on Local Epistatic Effects for Haplotype Construction Improves Power of Association Mapping

open access: yesG3: Genes, Genomes, Genetics, 2019
Genome-wide association studies (GWAS) have gained central importance for the identification of candidate loci underlying complex traits. Single nucleotide polymorphism (SNP) markers are mostly used as genetic variants for the analysis of genotype ...
Fang Liu   +3 more
doaj   +1 more source

ICAM-1 molecular mechanism and genome wide SNP's association studies

open access: yesIndian Heart Journal, 2015
Macrophages transformed foam cell formation occurs as a result of leukocyte accumulation mediated through intercellular adhesion molecule 1 (ICAM1), vascular cell adhesion molecule 1 (VCAM1), and E-selectin, secreted by inflamed or damaged endothelium ...
C. Anbarasan   +3 more
doaj   +1 more source

Genome-wide Association Study of Chicken Plumage Pigmentation [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2013
To increase plumage color uniformity and understand the genetic background of Korean chickens, we performed a genome-wide association study of different plumage color in Korean native chickens. We analyzed 60K SNP chips on 279 chickens with GEMMA methods
Mi Na Park   +8 more
doaj   +1 more source

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