Results 21 to 30 of about 850,713 (297)

Genome-Wide Association Studies of Asthma

open access: yesAllergology International, 2011
Bronchial asthma is a common inflammatory disease caused by a combination of genetic and environmental factors. To discover the genes and cellular pathways underlying asthma, a large number of genetic studies have been conducted.
Mayumi Tamari   +2 more
doaj   +1 more source

Selecting Closely-Linked SNPs Based on Local Epistatic Effects for Haplotype Construction Improves Power of Association Mapping

open access: yesG3: Genes, Genomes, Genetics, 2019
Genome-wide association studies (GWAS) have gained central importance for the identification of candidate loci underlying complex traits. Single nucleotide polymorphism (SNP) markers are mostly used as genetic variants for the analysis of genotype ...
Fang Liu   +3 more
doaj   +1 more source

Rare coding SNP in DZIP1 gene associated with late-onset sporadic Parkinson's disease [PDF]

open access: yes, 2011
We present the first application of the hypothesis-rich mathematical theory to genome-wide association data. The Hamza et al. late-onset sporadic Parkinson's disease genome-wide association study dataset was analyzed.
A Lerner   +47 more
core   +3 more sources

Developing Novel Therapeutic Strategies Against Ring Finger Protein 213 Vasculopathy: Is It an Achievable Goal?

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
See Article Choi et ...
Minghua Liu, Jose Gutierrez
doaj   +1 more source

ICAM-1 molecular mechanism and genome wide SNP's association studies

open access: yesIndian Heart Journal, 2015
Macrophages transformed foam cell formation occurs as a result of leukocyte accumulation mediated through intercellular adhesion molecule 1 (ICAM1), vascular cell adhesion molecule 1 (VCAM1), and E-selectin, secreted by inflamed or damaged endothelium ...
C. Anbarasan   +3 more
doaj   +1 more source

Genome-wide Association Study of Chicken Plumage Pigmentation [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2013
To increase plumage color uniformity and understand the genetic background of Korean chickens, we performed a genome-wide association study of different plumage color in Korean native chickens. We analyzed 60K SNP chips on 279 chickens with GEMMA methods
Mi Na Park   +8 more
doaj   +1 more source

A genome-wide association study of anorexia nervosa. [PDF]

open access: yes, 2014
Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by dangerously low body weight. Neither candidate gene studies nor an initial genome-wide association study (GWAS) have yielded significant and replicated results.
A A van Elburg   +218 more
core   +2 more sources

Genetic Pathways to Insomnia

open access: yesBrain Sciences, 2016
This review summarizes current research on the genetics of insomnia, as genetic contributions are thought to be important for insomnia etiology. We begin by providing an overview of genetic methods (both quantitative and measured gene), followed by a ...
Mackenzie J. Lind, Philip R. Gehrman
doaj   +1 more source

Genomic characterization and phylogenetic analysis of Salmonella enterica serovar Javiana [PDF]

open access: yesPeerJ, 2020
Salmonella enterica serovar Javiana is the fourth most reported serovar of laboratory-confirmed human Salmonella infections in the U.S. and in Tennessee (TN). Although Salmonella ser.
Lauren K. Hudson   +7 more
doaj   +2 more sources

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