Results 31 to 40 of about 43,083,361 (310)

Genome-Wide Association Study of Motor Coordination [PDF]

Frontiers in Human Neuroscience, 2021
The ability to finely control our movement is key to achieving many of the educational milestones and life-skills we develop throughout our lives. Despite the centrality of coordination to early development, there is a vast gap in our understanding of the underlying biology.
Mountford, HS, Hill, A, Barnett, AL, Newbury, DF   +3 more
openaire   +7 more sources

Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. [PDF]

, 2011
The prevalence of hypertension in African Americans (AAs) is higher than in other US groups; yet, few have performed genome-wide association studies (GWASs) in AA.
Keating, BJ, Boehnke, M., Lawrence, Robert W, Ridker, P.M., Alexander, M., Elosua, R., Zukowska-szczechowska, E., Philip Howard, Boerwinkle, E., Dong, Y., Parker, A.N., van der Schouw, Y.T., Hicks, Andrew A, Palmer, L.J., Zukowska-Szczechowska, Ewa, Palmer, N.D., Chris O'Donnell, Mangino, M., Colin A. McKenzie, Milaneschi, Yuri, Yen-Pei C. Chang, Toshiko Tanaka, Young, J. Hunter, Martin, Lisa W., Rettig, Rainer, Sudha Seshadri, Polak, J. F., Lathrop, Mark, Marmot, M. G., Josef F. Polak, Maciej Tomaszewski, Longstreth, Will T, Cooper, Richard S, Hedblad, Bo, Kuznetsova, T., Groop, L., Steve E. Humphries, Cooper, Richard S., Barroso, Inês, Rick Twee-Hee Ong, Cooper, J. A., Yoshikuni Kita, Ong, R.T., Loos, Ruth J F, Hugh Watkins, Vinay, D G, Chambers, John C, Schwartz, Steven M, Tai, E.S., Charles S. Janipalli, Janos Terzic, Mika Ala-Korpela, Altshuler, D., Keating, B., Maris Laan, Hofman, A., Igl, W., Daniel L. Dries, Smith, Albert V, Ongen, Halit, Thomas H. Mosley, Grassler, J., Seielstad, Mark, Heyo K. Kroemer, Miki, T., Vartiainen, Erkki, Steinle, N.I., Markku Laakso, EchoGen consortium, [Unknown], Keating, Brendan J, Ludwig, Barbara, Chang, Yen-Pei C, Bergman, R.N., Salako, T., Brand, E., Iwai, N., Salomaa, Veikko, Joel N. Hirschorn, Collins, Francis S, Go, M.J., Johnson, T, Wichmann, H.- E., Farlow, Deborah N., Hopewell, J. C., Hunt, S.C., Sue Shaw-Hawkins, Kurt K. Lohman, Orru, Marco, Najjar, S., Lehtimäki, Terho, Lori L. Bonnycastle, Tripathy, Vikal, Abbas Dehghan, Solomon K. Musani, Uitterlinden, Andre G, et al., Cuno S.P.M. Uiterwaal, Andrew D. Johnson, Valur Emilsson, Wong, T. Y., Larson, M. G., Mosley, Thomas H, Benjamin F. Voight, Laan, M., Navis, G., Michiel L. Bots, Farlow, D. N., Nalls, M.A., Zhang, W., Rice, K.M., Gyllensten, Ulf B, Mani, K Radha, Wyatt, S. B., Vitart, Veronique, Emilsson, V., Johannes Kettunen, Hercberg, S., Brown, Morris J, Nguyen, Khanh-Dung Hoang, Michael G. Marmot, Rao, D. C., John C. Chambers, Voight, B. F., Franceschini, N, Aravinda Chakravarti, Scuteri, Angelo, Lucas, Gavin, Sun, Y.V., Khanh-Dung Hoang Nguyen, Santhi Ganesh, Dominiczak, Anna F, Caulfield, M.J., Wright, A.F., Talmud, Philippa J, Forrester, Terrence, Kooner, J.S., Robert W. Lawrence, Cooper, M. N., Hadley, D., Gaunt, T.R., Lyon, HN, Fernando Rivadeneira, Jaakko Tuomilehto, Talmud, P.J., Gyllensten, U. B., George Davey Smith, Ulf B. Gyllensten, Lyon, Helen N, Longstreth, W.T., Shih-Jen Hwang, Wareham, N.J., Eaton, C. B., Li, Y., Toshio Ogihara, Kooner, Jaspal S, Giuseppe Matullo, Peter P. Pramstaller, Pihur, V., Steinle, N. I., Burton, P.R., Heath, S., Mariacorsi, A., Verwoert, G. C., Erdmann, Jeanette, Nicholas J. Wareham, Eva Brand, Samani, N. J., Artigas, M.S., Sharma, Pankaj, Xiaofeng Zhu, Galan, P., Li, YL, van Gilst, Wiek H, Van Der Harst, P., Vineis, P., Collins, F.S., Tai, E Shyong, Jackson, A.U., Grässler, Jürgen, Wilson, James F, Palmer, Lyle J, Danish Saleheen, Whincup, P.H., Lee, J.-y., Tukiainen, T., Okamura, T., Garcia, M., Dong, Yanbin, Dorairajan Prabhakaran, Judith A. Hoffman Bolton, Kang, S.J., Casas, J. P., Dehghan, Abbas, Kroemer, H. K., KidneyGen consortium, [Unknown], Penman, Alan D., Bamidele O. Tayo, Melissa Garcia, Verwoert, Germaine C, Perola, Markus, Cristian Pattaro, Köttgen, Anna, Rice, K. M., Alex N. Parker, Vinay, DG, Islam, M., McKenzie, Colin A, Van Der Schouw, Y. T., Toby Johnson, Meschia, James F, Hercberg, Serge, Longstreth, W. T., Pramstaller, P. P., Parker, A. N., Bornstein, S. R., Beckmann, Jacques S, Hicks, A.A., Min JinGo, Volker, U., Susana Eyheramendy, Fox, Ervin R., Hartikainen, A.-l., Will T. Longstreth, Townsend, R.R., Brand, Eva, Jacques S. Beckmann, Anna-Liisa Hartikainen, Polasek, Ozren, Kumari, M., Nish Chaturvedi, Lynne E. Wagenknecht, Polak, J., Louise V. Wain, Tzoulaki, I., Jing Hua Zhao, Soininen, P., Penman, A. D., Sehmi, J.S., Anna Köttgen, Mosley, Thomas H., Luan, J., Cristiano Fava, Rotter, J.I., Steven C. Hunt, Psaty, B. M., Alanna C. Morrison, Ehret, Georg B, Gavin Lucas, Debbie A. Lawlor, Hoffman Bolton, Judith A, Heckbert, S. R., Umemura, Satoshi, Mosley, T.H., Wild, Sarah H, Jackson, Anne U, Townsend, RR, Raitakari, Olli, JinGo, Min, Rudan, I., Snieder, Harold, Stephan J.L. Bakker, Thomas J. Wang, Annika Rosengren, Stancakova, A., Fabsitz, R. R., Connell, John M, Kangas, A.J., Eyheramendy, Susana, Tim D. Spector, Palmas, W, Dag S. Thelle, Megan E. Rudock, Van Gilst, W. H., Stancáková, Alena, Thor Aspelund, Shaw-hawkins, S., Ehret, G. B., Hernandez, Dena, Shrine, N.R., Ramachandran, Vasan S, Oostra, Ben A, Andrew Taylor, Kivimaki, M., Chen, M.H., Hyung-Lae Kim, Keating, B. J., Kooner, J. S., Zhao, J. H., Yajnik, C. S., Volzke, H., Wilmar Igl, Dominiczak, A. F., Laakso, Markku, Peden, J. F., Ewa Zukowska-Szczechowska, Jaspal S. Kooner, Polak, JF, Smita R. Kulkarni, Thomas Meitinger, Coresh, J., Hadley, David, Zhu, Haidong, Kardia, S. L. R., Elliott, P., O'Connell, Jeffrey R, Laitinen, J., Veldre, G., Palmer, L. J., Nanette I. Steinle, Casas, J.P., Palmas, W., Hilton, Gina, Helen N. Lyon, Swift, A. J., Bornstein, Stefan R, Altshuler, David, Matthias Olden, Chen, M.-h., Rotimi, C. N., Doumatey, AP, Newton-cheh, C., Francis S. Collins, Hwang, Shih-Jen, Uiterwaal, C.S., Luan, Jian'an, Chandak, G. R., Launer, Lenore, Salako, Tunde, Panos Deloukas, Stringham, Heather M, Najaf Amin, Farlow, DN, Beilby, John P, Vinay, D. G., Smith, N.L., Jennifer L. Bragg-Gresham, Elosua, Roberto, Caulfield, Mark J., Dries, D. L., Tuomilehto, J., Swift, Amy J, Uiterwaal, C. S. P. M., Taylor, Herman A, Munroe, Patricia B, Serge Hercberg, Morrison, Alanna C, Fadi J. Charchar, Arfan Ikram, M., Germaine C. Verwoert, Bok-Ghee Han, Sharon B. Wyatt, Soininen, Pasi, Kardia, Sharon L R, Carl D. Langefeld, Andrew A. Hicks, Farlow, D., Bis, Joshua C, Kang, Sun J., Roberto Elosua, Andre G. Uitterlinden, Curb, J. David, Ehret, G.B., Albert W. Dreisbach, Prabhakaran, D., Salomaa, V., Parsa, Afshin, Dreisbach, AW, Dries, DL, Mohlke, K.L., Campbell, Harry, Platou, C. G. P., Kinra, S., Nguyen, K.-d. H., Hirschorn, J.N., Kivimaki, Mika, Narisu, Narisu, Hingorani, A.D., Afshin Parsa, Johnson, A.D., Fabsitz, R.R., Vollenweider, P., Rasheed, Asif, Linda S. Adair, Voight, Benjamin F, Kardia, SLR, Scott, J., Cho, Y. S., Guo, X., Newton-Cheh, Christopher, Mcardle, W. L., Kuh, Diana, Leena Peltonen, Arking, D.E., McKenzie, C.A., Bochud, M., Wain, L. V., Dries, D., Plump, A., Kulkarni, Smita R, Nilsson, Peter, Meitinger, T., Doumatey, Ayo P, Ozren Polasek, Dreisbach, A., Jeanette Erdmann, Mario A. Morken, Parsa, A., Takayoshi Ohkubo, Kardia, Sharon L.R., Han, Bok-Ghee, Shrine, N. R. G., Albert V. Smith, Smith, A.V., Gonçalo R. Abecasis, Yajnik, C.S., Rosengren, A., Inga Prokopenko, David P. Strachan, Nora Franceschini, Wareham, Nicholas J, Young, J.H., Stringham, H. M., Adeyemo, A, Barroso, I., Smith, G.D., Jan A. Staessen, Kita, Y., Franceschini, N., Nalls, M. A., Vilmundur Gudnason, Tetsuro Miki, Smith, G. D., Lohman, K.K., Guangju Zhai, Young, J Hunter, Mattace-Raso, Francesco U S, Tom R. Gaunt, Alexander, Myriam, Zhu, X, Hingorani, A. D., Langefeld, C.D., Ramachandran, V.S., Lyytikäinen, Leo-Pekka, Wang, Thomas J, Doumatey, Ayo P., Bis, J.C., Wilson, J.F., Okamura, Tomonori, Myriam Alexander, Gerjan Navis, Mattace-raso, F. U. S., Raitakari, O., Rudock, Megan E, International Consortium for Blood Pressure Genome-Wide Association Studies, Connell, J. M., Feng Zhang, Adair, L. S., Beckmann, J. S., Lyytikäinen, L.P., Wong, Tien Y, Gina Hilton, E. Shyong Tai, Scott, Laura J, Peltonen, Leena, Lohman, K. K., Soranzo, N., John F. Peden, Dominiczak, A.F., Charchar, F. J., Tayo, B.O., Dreisbach, Albert W., Lawlor, D.A., Rotter, J. I., Kahonen, M., Boehnke, Michael, Ian N.M. Day, Palmas, Walter, Campbell, H., Eaton, CB, Coresh, Josef, Scott, James, Barbara Ludwig, Heather M. Stringham, Isaacs, A., O'reilly, P. F., Bergman, R. N., CARDIoGRAM consortium, [Unknown], Zitting, Paavo, Hwang, S.J., Levy, D, Wilson, James F; id_orcid, Corsi, Anna Maria, Shuldiner, A. R., O'Reilly, P.F., Lawrence, R. W., Bergmann, S., Pattaro, C., Khaw, K.-t., Stefan R. Bornstein, Collins, R., Frayling, Timothy M, Farrall, M., Teumer, Alexander, Umemura, S., Matullo, G., Martin, Lisa W, Pattaro, Cristian, Leo-Pekka Lyytikäinen, Li, Y, Ehret, Georg B., Nicole L. Glazer, Aroon D. Hingorani, Abecasis, Gonçalo R, Emilsson, Valur, Gaunt, T. R., Tomonori Okamura, Heckbert, S.R., Ming-Huei Chen, Ramachandran, V. S., Gang Shi, Wendy L. McArdle, Collins, F. S., Jutta Palmen, Nilesh J. Samani, Lakatta, Edward G, Veikko Salomaa, Townsend, R. R., Fava, C., Wang, T.J., Lawlor, D. A., Morrison, A., Chambers, J.C., Khaw, Kay-Tee, Yurii Aulchenko, Wu, Ying, Wain, L.V., Chandak, Giriraj R, Muhammad Islam, Viigimaa, M., Day, I.N., Raffel, Leslie J, Kristian Hveem, Taylor, A., Liu, Yongmei, Gerald R. Fowkes, Musani, Solomon K, Soler Artigas, Maria, Samani, Nilesh J, Sekar Kathiresan, Kardia, S.L., Musani, Solomon K., Alan B. Weder, Hirschhorn, J.N., McArdle, W.L., Vollenweider, Peter, Melander, O., Meneton, P., Cooper, J.A., Wong, T.Y., Morrison, AC, Soranzo, Nicole, Hayward, Caroline, Palmer, N. D., Albert Hofman, Ohkubo, T., O'Donnell, Chris, Zelenika, Diana, Voight, B.F., Redline, Susan, Yali Li, Igl, Wilmar, Wild, S. H., Kottgen, A., Morris J. Brown, Farlow, D.N., Iwai, Naoharu, Würz, Peter, Gieger, Christian, Yao, Jie, Kroemer, H.K., Ala-Korpela, Mika, Rotimi, C.N., Viikari, Jorma, Penman, Alan D, Caulfield, MJ, Sim, X., Simonetta Guarrera, Bonnycastle, L.L., Bakker, S. J. L., Mosley, T. H., Kranthi Kumar, M. J., Lyle J. Palmer, M.J. Kranthi Kumar, Fox, E.R., Liu, Kiang, Chakravarti, Aravinda, Fredrik Nyberg, Schwartz, S.M., John M. Connell, Kuusisto, Johanna, Wagenknecht, L.E., Morken, M.A., Adeyemo, A., Alexander Teumer, Alan R. Shuldiner, Grobbee, D. E., Morris, Richard W, Lakatta, E.G., Amin, N., Nyberg, Fredrik, Dreisbach, A.W., Oostra, B.A., Mika Kivimaki, Watkins, Hugh, Morrison, A.C., Harris, T. B., Meschia, J. F., Christian Gieger, Sijbrands, E. J. G., Bergman, Richard N, J. David Curb, Polak, Josef F., Thelle, Dag S, Morken, Mario A, Ioanna Tzoulaki, Raymond R. Townsend, Jafar, T.H., Aspelund, Thor, Polak, J.F., Michael Boehnke, Redline, S., Jackson, A. U., Viigimaa, Margus, Saleheen, Danish, Kim, H.-l., Hardy, Rebecca, Spector, T.D., Sijbrands, E.J., Forrester, T., Navis, Gerjan, Howard, P., Isaacs, Aaron, Verwoert, G.C., Rice, Kenneth M, Kathiresan, Sekar, Larson, Martin G, Tomaszewski, M., Hingorani, Aroon D, Lakatta, E. G., Markus Perola, Loos, R.J., Gyllensten, U.B., Alena Stančáková, Perola, M., Peter Nilsson, Jemma C. Hopewell, Alan D. Penman, Ruth J.F. Loos, Staessen, J. A., Ala-korpela, M., Haidong Zhu, Fabsitz, Richard R, Francesco U.S. Mattace-Raso, Musani, S.K., Abecasis, G. R., Tien Y. Wong, Aulchenko, Yurii, Robert Clarke, Maria SolerArtigas, Jafar, Tazeen H, Arora, P., Chasman, D.I., Janipalli, C. S., Karen L. Mohlke, Kangas, Antti J, Dabeeru C. Rao, Hwang, S.-j., Adair, Linda S, N. Charlotte Onland-Moret, Richard S. Cooper, Anne U. Jackson, Kulkarni, S.R., Gaunt, Tom R, Kutlar, A., Sõber, Siim, Lee, N.R., Leif Groop, Wain, Louise V, Yan V. Sun, Hopewell, J.C., Prabhakaran, Dorairajan, Palmen, J., Staessen, Jan A, Bragg-gresham, J. L., Lucas, G., Terho Lehtimäki, Nanette R. Lee, Fowkes, G. R., Tuomilehto, Jaakko, Paolo Vineis, Solerartigas, M., Richard W. Morris, Kumari, Meena, Eric J.G. Sijbrands, Eaton, C.B., Asif Rasheed, Vartiainen, E., Uda, M., Kroemer, Heyo K, Susan R. Heckbert, Connell, J.M., Ehret, GB, Eaton, Charles B., Morken, M. A., Harris, Tamara B, Kathiresan, S., O'Reilly, Paul F, Amin, Najaf, Kettunen, Johannes, Ganesh, S., Chang, Y.-p. C., H.-Erich Wichmann, Langefeld, Carl D, Elliott, Paul, Zhai, G., Siim Sõber, Dorr, M., Shi, Gang, Shrine, Nick R G, Zhu, H., Kenneth M. Rice, Humphries, S.E., Kardia, SL, Laan, Maris, J. Hunter Young, Bots, M. L., Pankaj Sharma, Vikal Tripathy, Cooper, Matthew N, Samani, N., Peter Vollenweider, Hicks, A. A., Terzic, J., Ganesh, S, Yoon Shin Cho, Ben A. Oostra, Swift, A.J., Eaton, Charles B, Schwarz, P. E. H., Manuela Uda, Matullo, Giuseppe, Sehmi, J. S., Palmer, Nicholette D, Demirkan, A., Bochud, Murielle, Weder, A.B., Boerwinkle, Eric, Humphries, Steve E, Jacqueline C.M. Witteman, Beilby, J.P., Wyatt, Sharon B, Wichmann, H.E., Martin Farrall, Hveem, K., Martin D. Tobin, Paul R. Burton, Mooser, Vincent, Mohlke, K. L., Curb, J David, Cooper, M.N., Heckbert, Susan R, Eyheramendy, S., Bandinelli, S., Taylor, HA, Orru, M., Tayo, BO, Hunt, S. C., Ervin R. Fox, Aspelund, T., Liu, K, Morrison, A. C., Levy, Daniel, Tamara B. Harris, oel, Anuj, Wichmann, H-Erich, Cooper, RS, Bonnycastle, L. L., Wong, A., Taylor, H. A., Xueling Sim, Watkins, H., Charchar, F.J., Nicholette D. Palmer, Wagenknecht, L. E., Wright, Alan F, Diederick E. Grobbee, ICBP Consortium (Meitinger, T. ; Wichmann, H.-E.), Vineis, Paolo, Brown, M.J., Narisu, N., Mark J. Caulfield, Yuri Milaneschi, Ueshima, Hirotsugu, Jerome I. Rotter, Lee, J.Y., Danesh, J., Bots, Michiel L, Sanjay Kinra, Paul M. Ridker, Campbell, Harry; id_orcid, Wiggins, K.L., Kuznetsova, Tatiana, Chandak, G.R., Chasman, Daniel I, Johnson, A. D., Peter S. Braund, Singleton, Andrew, Lehtimaki, T., Ridker, P. M., Johnson, T., Tazeen H. Jafar, ?, ?, Zhao, Jing Hua, Kao, W. H. L., O'donnell, C., Kao, Wen Hong Linda, Witteman, Jacqueline C M, Townsend, Raymond R., Martin G. Larson, Shuldiner, A.R., Rudock, M.E., Rotimi, Charles N, Mark Lathrop, Arking, Dan E, Musani, SK, Musani, S., Seshadri, S., Platou, C.G., Tzoulaki, Ioanna, Hilton, G., Fowkes, F Gerald R, Mark Seielstad, Caulfield, M. J., Wiggins, Kerri L, Uda, Manuela, John P. Beilby, Ying Wu, Guo, Xiuqing, Bandinelli, Stefania, Bakker, S.J., Prokopenko, Inga, International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS), Fulvio Ricceri, Dena Hernandez, Narisu Narisu, Ikram, M Arfan, Bergmann, Sven, Daniel I. Chasman, Rasheed, A., Tobin, M.D., Richard R. Fabsitz, Adair, L.S., Martin, LW, Scuteri, A., Palmen, Jutta, Adebowale Adeyemo, Abecasis, G.R., Sun J. Kang, Rao, Dabeeru C, Dreisbach, Albert W, Chittaranjan S. Yajnik, Peter Würz, Rotimi, CN, Taru Tukiainen, Ueshima, H., Wurz, P., Rotter, Jerome I, Chen, Ming-Huei, Alan F. Wright, Kang, S. J., Kuh, D., Franceschini, Nora, Andrew Wong, Goel, A., Stringham, H.M., Lyon, H. N., Marco Orru, Janipalli, C., Vincent Mooser, Curb, J. D., Fox, E., Kardia, Sharon LR, Andrew Singleton, Curb, J.D., Laakso, M., Hunt, Steven C, Dörr, Marcus, Juan P. Casas, Terzic, Janos, Erdmann, J., Arora, Pankaj, Murielle Bochud, Vasyl Pihur, Kuusisto, J., van Duijn, C.M., Philippa J. Talmud, Wagenknecht, Lynne E, Levy, D., Chambers, J. C., Parker, Alex N, Sjögren, Marketa, Simon Heath, Paavo Zitting, Fowkes, F.G., Raffel, L.J., Hirschorn, Joel N., Anders Hamsten, Bornstein, S.R., Adeyemo, Adebowale, van der Harst, Pim, Loos, R. J. F., Jafar, T. H., Sun, Yan V, Luigi Ferrucci, Ludwig, B., Corsi, A.M., Schwarz, P.E., Kähönen, Mika, Tobin, Martin D, Anuj Goel, Paul Elliott, Sun, Yan V., Mika Kähönen, Witteman, J. C. M., Jie Yao, Uitterlinden, A. G., Stefan-Martin Brand, Deloukas, P., Wang, T. J., Fox, ER, Weder, Alan B, Frayling, T. M., Dehghan, A., CKDGen consortium, [Unknown], Guarrera, Simonetta, Teumer, A., Pim van der Harst, Joban S. Sehmi, James Scott, Andrew Plump, Wareham, N. J., Sjogren, M., Beckmann, J.S., Bragg-Gresham, J.L., Kao, W.H., Kinra, Sanjay, Shuldiner, Alan R, Plump, Andrew, Daniel Levy, Polasek, O., Lohman, Kurt K, Hirschorn, J. N., Wyatt, S.B., International Consortium for Blood Pressure Genome-wide Associat, Munroe, P.B., Kita, Yoshikuni, Amy J. Swift, Kutlar, Abdullah, Wild, Sarah H; id_orcid, Jackie A. Cooper, Taylor, Andrew, Grobbee, Diederick E, Nalls, Michael A, Seielstad, M., Ayo P. Doumatey, Wu, Y., Zhang, Feng, Glazer, N. L., David Altshuler, Marmot, Michael G, Deloukas, Panos, Rosengren, Annika, Twee-hee Ong, R., Ohkubo, Takayoshi, Margus Viigimaa, O'Connell, J.R., Steinle, Nanette I, Laura J. Scott, Saleheen, D., Laitinen, Jaana, Rory Collins, Jarvelin, M.-r., Burton, P. R., Go, Min Jin, Collins, Rory, Talmud, P. J., Kim, H.L., Hofman, Albert, Zhao, J.H., Yongmei Liu   +999 more
core   +2 more sources

Transcriptome-wide association study identified candidate genes associated with gut microbiota

Gut Pathogens, 2021
Background Gut microbiota is closely associated with host health and disease occurrence. Host genetic factor plays an important role in shaping gut microbial communities.
Chuyu Pan, Yujie Ning, Yumeng Jia, Shiqiang Cheng, Yan Wen, Xuena Yang, Peilin Meng, Chun’e Li, Huijie Zhang, Yujing Chen, Jingxi Zhang, Zhen Zhang, Feng Zhang   +12 more
doaj   +1 more source

Transcriptome‐wide association study identifies multiple genes and pathways associated with pancreatic cancer

Cancer Medicine, 2018
Aim To identify novel candidate genes for pancreatic cancer. Methods We performed a transcriptome‐wide association study (TWAS) analysis of pancreatic cancer (PC).
Liuyun Gong, Dan Zhang, Yutiantian Lei, Yuanjie Qian, Xinyue Tan, Suxia Han   +5 more
doaj   +1 more source

A genome-wide association study identifies protein quantitative trait loci (pQTLs) [PDF]

, 2008
There is considerable evidence that human genetic variation influences gene expression. Genome-wide studies have revealed that mRNA levels are associated with genetic variation in or close to the gene coding for those mRNA transcripts - cis effects, and ...
Marjo-Riitta Jarvelin, Simon-Sanchez, J, Hana Lango, Henley W, Greg Tranah, HURST A., Singleton, A, Murray, A, WEEDON M., McCarthy, Mark I, Rafferty I, Lango H, David Melzer, Rafferty, Ian, Singleton A, Bandinelli, S, Bennett, A, BRITTON A., Hurst, A, Newman, Anne B, van de Leemput J, Colin Dayan, GIBBS J., Paolisso, G, Lango, H, Dayan, Colin; id_orcid, Hurst A, Anne B Newman, Murray, Anna, FRAYLING T., Tranah, G, Panicker, V, Perry, John R. B., SHOLZ S., Frayling, Timothy M., Ferrucci, Luigi, Scholz, Sonja, Corsi AM, RICE N., Simon-Sanchez J, J Raphael Gibbs, Tranah G, Harris, Tamara, Jarvelin, Marjo-Riitta, Ruokonen A, Jarvelin, Marjo Riitta, Melzer, D, Paolisso G, Javier Simon-Sanchez, AREPALLI S., Amanda Bennett, Timothy M Frayling, Murray A, Scholz, S, Hernandez D, Fulvio Lauretani, Hurst, Alison, Singleton, Andrew, RAFIQ S., Jarvelin MR, Rafiq S, McCarthy, MI, Rafiq, S, Arepalli, S, van de Leemput, Joyce, PANICKER V., TRANAH G., Guralnik, J, Stevens K, Melzer, David, Rongling Li, Giuseppe Paolisso, Gibbs, J. Raphael, STEVENS K., Sajjad Rafiq, Corsi, Anna Maria, Perry JRB, Bennett A, Harris, T, Perry, John R.B., Bandinelli, Stefania, Nicole Washecka, Lauretani, Fulvio, Lango, Hana, Dena Hernandez, Harris T, Scholz S, McCarthy, Mark I., Frayling, Timothy M, William Henley, HARRIS T., Guralnik J, Stevens, K, Panicker, Vijay, Jack Guralnik, Li, R, DAYAN C., McCarthy MI, Rice N, Weedon, Michael N., Sampath Arepalli, Dayan C, Guralnik, Jack, Lauretani, F, John R B Perry, Melzer D, Dayan, C, Newman, Anne B., Lauretani F, RAFFERTY I., Britton A, Newman AB, Sonja Scholz, Angela Britton, HERNANDEZ D., Frayling TM, Corsi, Anna-Maria, Britton, A, Washecka, Nicole, Andrew Singleton, Ferrucci, L, Tamara Harris, LANGO H., Gibbs, JR, BENNET A., Perry, JRB, Dayan, Colin Mark, Michael N Weedon, Weedon, Michael N, Luigi Ferrucci, Bennett, Amanda, Neil Rice, Rice, N, Anna-Maria Corsi, BANDINELLI S., Washecka, N, Henley, William, Ruokonen, Aimo, Henley, W, Gibbs JR, SIMON SANCHEZ J., Kara Stevens, Arepalli, Sampath, Stevens, Kara, Joyce van de Leemput, MELZER D., Weedon MN, Frayling, TM, Panicker V, SINGLETON A., Weedon, MN, Dayan, Colin, Jarvelin, MR, Anna Murray, Arepalli S, Ferrucci L, FERRUCCI L., Rice, Neil, Li, Rongling, Tranah, Greg, Washecka N, HENLEY W., MCCARTHY M., Perry, John RB, Ruokonen, A, JARVELIN M., Li RL, VAN DE LEEMPUT J., Rafiq, Sajjad, PERRY J., Hernandez, Dena, WASHECKA N., Mark I McCarthy, Vijay Panicker, Ian Rafferty, MURRAY A., LI R., Newman, AB, Bandinelli S, NEWMAN A., Gibbs, J Raphael, Paolisso, Giuseppe, GURALNIK J., Hernandez, D, CORSI A., Van De Leemput, J, Simon-Sanchez, Javier, Stefania Bandinelli, Alison Hurst, RUOKONEN A., Corsi, AM, Britton, Angela, Rafferty, I, Aimo Ruokonen, et al,   +194 more
core   +1 more source

Guidelines for Genome-Wide Association Studies

PLoS Genetics, 2012
Genome-wide association studies (GWAS) have revolutionized human genetics. They have led to the identification of thousands of loci that affect both normal variation and susceptibility to disease, and have clarified our understanding of the genetic architecture of complex traits.
Gregory S Barsh, Gregory P Copenhaver, Greg Gibson, Scott M Williams   +3 more
openaire   +4 more sources

Replication in Genome-Wide Association Studies

Statistical Science, 2009
Replication helps ensure that a genotype-phenotype association observed in a genome-wide association (GWA) study represents a credible association and is not a chance finding or an artifact due to uncontrolled biases. We discuss prerequisites for exact replication, issues of heterogeneity, advantages and disadvantages of different methods of data ...
Kraft, Peter, Zeggini, Eleftheria, Ioannidis, John P. A.   +2 more
openaire   +6 more sources

Genome-Wide Association Studies of Cancer [PDF]

Journal of Clinical Oncology, 2010
Knowledge of the inherited risk for cancer is an important component of preventive oncology. In addition to well-established syndromes of cancer predisposition, much remains to be discovered about the genetic variation underlying susceptibility to common malignancies. Increased knowledge about the human genome and advances in genotyping technology have
Zsofia K, Stadler, Peter, Thom, Mark E, Robson, Jeffrey N, Weitzel, Noah D, Kauff, Karen E, Hurley, Vincent, Devlin, Bert, Gold, Robert J, Klein, Kenneth, Offit   +9 more
openaire   +2 more sources

Data mining and machine learning approaches for the integration of genome-wide association and methylation data: methodology and main conclusions from GAW20

BMC Genetics, 2018
Background Multiple layers of genetic and epigenetic variability are being simultaneously explored in an increasing number of health studies. We summarize here different approaches applied in the Data Mining and Machine Learning group at the GAW20 to ...
Burcu Darst, Corinne D. Engelman, Ye Tian, Justo Lorenzo Bermejo   +3 more
doaj   +1 more source

Genome-Wide Association Study Identifies Novel Restless Legs Syndrome Susceptibility Loci on 2p14 and 16q12.1 [PDF]

, 2011
Restless legs syndrome (RLS) is a sensorimotor disorder with an age-dependent prevalence of up to 10% in the general population above 65 years of age. Affected individuals suffer from uncomfortable sensations and an urge to move in the lower limbs that ...
Juliane Winkelmann, Sona Nevsimalova, Dauvilliers, Yves, Bachmann, Cornelius G., Wichmann, H. -Erich, Knauf F, Wichmann HE, Gschliesser V, Kettunen Johannes, Fontaine, B., Vávrová J, Müller-Myhsok, B., Montplaisir Jacques, Ondo, William, G., Czamara, D., Le Wei-Dong, Bertram Müller-Myhsok, Schulte, E.C., Birgit Högl, Fietze Ingo, Stiasny-Kolster, Karin, Kettunen, Johannes, Kaffe M, Müller Myhsok B, Vodicka, P., H.-Erich Wichmann, Vilariño-Güell, Carles, Wichmann, H.-E., Gschliesser, V., Perola Markus, Xiong, L., Illig Thomas, Silander, K., Fontenille C, Berger K, Bertram Müller-Myhsok, Berger, K., Cournu Rebeix I, Kaffe, Maria, Sonka K, Faraco J, Mueller-Myhsok, Bertram, Maria Kaffe, Sonka, K., Müller-Myhsok Bertram, Earley CJ, Cournu-Rebeix Isabelle, Kemlink David, Stiasny Kolster K, Vilariño-Güell Carles, Poewe Werner, Kaffe Maria, Ondo William G., Lichtner, P., Zimprich A, Fietze, I., Fontaine Bertrand, Bachmann, C.G., Farrer, Matthew J., Olli Polo, Vavrova, J., Hoegl, Birgit, Cournu-Rebeix, I., Oertel Wolfgang, Högl Birgit, Kettunen J, Zimprich, A., Meitinger, T., Fontaine, Bertrand, Högl, B., Richard P. Allen, Faraco, J., William G. Ondo, Lin Siong-Chi, Oertel, Wolfgang, Allen, Richard P., Meitinger T., Fuhs, Andrea, Cornelius G. Bachmann, Wichmann, H-Erich, Wszolek Zbigniew, Perola M, Polo, Olli, Meitinger Thomas, Darina Czamara, Xiong L, Siong-Chi Lin, Allen, R., Knauf, F., Le, Wei-Dong, Gross Nadine, Bachmann, C., Gieger, C., Berger, Klaus, Cournu-Rebeix, Isabelle, Matthew J Farrer, Paulus Walter, Peppard P, Stiasny-Kolster, K., Winkelmann, Juliane, Fietze I, Francavilla Marcella, Schulte, Eva C., Carles Vilariño-Güell, Walter Paulus, Christopher J Earley, Dauvilliers Y, Gieger C, Werner Poewe, Gieger Christian, Frauscher Birgit, Bachmann CG, Wolfgang Oertel, Ondo, W.G., Schulte EC, Guy A Rouleau, Falkenstetter Tina, Klaus Berger, Trenkwalder C, Earley, Christopher J., Fontenille, Claire, Faraco, Juliette, Prokisch, Holger, Juliette Faraco, Paulus, Walter J., Farrer Matthew J., Bertrand Fontaine, Schulte, E., Paulus, W., Ondo, W., Montplaisir, Jacques, Paul Peppard, Trenkwalder Claudia, Illig T, Dauvilliers, Y., Schulte Eva C., Wichmann, H., Thomas Illig, Silander, Kaisa, Winkelmann, J., Paulus W, Johannes Kettunen, Spieler D, Jacques Montplaisir, Peppard Paul, Frauscher B, Earley, C., Zimprich, Alexander, Alexander Zimprich, Falkenstetter, T., Le WD, Fontenille Claire, Rouleau, G.A., Czamara, Darina, Schormair, Barbara, Vodicka P, Spieler, Derek, Karel Sonka, William G Ondo, Paulus, Walter, Peppard, P., Guy A. Rouleau, Frauscher, B., Montplaisir, J., Trenkwalder, Claudia, Marcella Francavilla, Le, W.D., Vilarino-Guell, C., Lin, S., Vilariño Güell C, Poewe, W., Le, W., Prokisch Holger, Fuhs, A., Högl B, Lichtner Peter, Wszolek, Z., Sonka Karel, Wei-Dong Le, Illig, T., Earley, Christopher, J., Fontaine B, Vodicka Pavel, Mignot Emmanuel, Kaffe, M., Faraco Juliette, Barbara Schormair, Christopher J. Earley, Francavilla, M., Kaisa Silander, Xiong, Lan, Schormair B, Ingo Fietze, Prokisch, H., Gschliesser, Viola, Viola Gschliesser, Yves Dauvilliers, Mignot, Emmanuel, Emmanuel Mignot, Kemlink, D., Peter Lichtner, Polo O, Lichtner, Peter, Rouleau, Guy, A., Allen Richard P., Czamara D, Schulte, Eva, C., Karin Stiasny-Kolster, Knauf, Franziska, H-Erich Wichmann, Mignot, E., Lin, Siong-Chi, Zbigniew Wszolek, Perola, Markus, Müller-Myhsok, Bertram, Tina Falkenstetter, Rouleau, Guy A., Gieger, Christian, Fietze, Ingo, Nevsimalova Sona, Lan Xiong, David Kemlink, Derek Spieler, Carles Vilariño-Güell, Zimprich Alexander, Allen RP, Eva C Schulte, Nevsimalova, Sona, Earley, C.J., Farrer, Matthew, J., Czamara Darina, Lin, S.C., Richard P Allen, Allen, R.P., Wichmann, Heinz-Erich, Montplaisir J, Gross, N., Poewe W, Allen, Richard, P., Vávrová Jana, Prokisch H, Christian Gieger, Francavilla, Marcella, Vavrova, Jana, Franziska Knauf, Matthew J. Farrer, Dauvilliers Yves, Rouleau Guy A., Ondo WG, Gross, Nadine, Rouleau GA, Wszolek Z, Schormair Barbara, Falkenstetter T, Eva C. Schulte, Kemlink, David, Ondo, William G., Bachmann, Cornelius, G., Sonka, Karel, Kemlink D, Nevsimalova, S., Andrea Fuhs, Cornelius G Bachmann, Trenkwalder, C., Oertel, W., Farrer MJ, Falkenstetter, Tina, Poewe, Werner, Högl, Birgit, Bachmann Cornelius G., Wichmann H.-Erich, Schormair, B., Claudia Trenkwalder, Xiong Lan, Polo, O., Oertel W, Markus Perola, Farrer, M., Perola, M., Silander Kaisa, Polo Olli, Stiasny-Kolster Karin, Isabelle Cournu-Rebeix, Winkelmann J, Mignot E, Gschliesser Viola, Fontenille, C., Frauscher, Birgit, Nadine Gross, Berger Klaus, Illig, Thomas, Jana Vávrová, Meitinger, Thomas, Fuhs A, Winkelmann Juliane, Rouleau, G., Fuhs Andrea, Farrer, M.J., Earley Christopher J., Peppard, Paul, Birgit Högl, Vodicka, Pavel, Thomas Meitinger, Gross N, Birgit Frauscher, Spieler Derek, Lichtner P, Lin SC, Kettunen, J., Vilarino-Gueell, Carles, Pavel Vodicka, Spieler, D., Silander K, Wszolek, Zbigniew, Nevsimalova S, Claire Fontenille, Holger Prokisch, Knauf Franziska, Jana Vávrová, Rouleau, Guy,, Bachmann, Cornelius,, Schulte, Eva,, Earley, Christopher,, Farrer, Matthew,, Ondo, William,, Allen, Richard,, Winkelmann, J;Czamara, D;Schormair, B;Knauf, F;Schulte, EC;Trenkwalder, C;Dauvilliers, Y;Polo, O;Högl, B;Berger, K;Fuhs, A;Gross, N;Stiasny-Kolster, K;Oertel, W;Bachmann, CG;Paulus, W;Xiong, L;Montplaisir, J;Rouleau, GA;Fietze, I;Vávrová, J;Kemlink, D;Sonka, K;Nevsimalova, S;Lin, SC;Wszolek, Z;Vilarino-Guell, C;Farrer, MJ;Gschliesser, V;Frauscher, B;Falkenstetter, T;Poewe, W;Allen, RP;Earley, CJ;Ondo, WG;Le, WD;Spieler, D;Kaffe, M;Zimprich, A;Kettunen, J;Perola, M;Silander, K;Cournu-Rebeix, I;Francavilla, M;Fontenille, C;Fontaine, B;Vodicka, P;Prokisch, H;Lichtner, P;Peppard, P;Faraco, J;Mignot, E;Gieger, C;Illig, T;Wichmann, HE;Müller-Myhsok, B;Meitinger, T   +326 more
core   +2 more sources