Results 31 to 40 of about 1,303,219 (221)
Replication in Genome-Wide Association Studies
Statistical Science, 2009 Replication helps ensure that a genotype-phenotype association observed in a genome-wide association (GWA) study represents a credible association and is not a chance finding or an artifact due to uncontrolled biases. We discuss prerequisites for exact replication, issues of heterogeneity, advantages and disadvantages of different methods of data ...
Kraft, Peter +2 more
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Brain Sciences, 2016 This review summarizes current research on the genetics of insomnia, as genetic contributions are thought to be important for insomnia etiology. We begin by providing an overview of genetic methods (both quantitative and measured gene), followed by a ...
Mackenzie J. Lind, Philip R. Gehrman
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A genome-wide association study of aging
Neurobiology of Aging, 2011 Human longevity and healthy aging show moderate heritability (20%-50%). We conducted a meta-analysis of genome-wide association studies from 9 studies from the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium for 2 outcomes: (1) all-cause mortality, and (2) survival free of major disease or death.
Jerome I. Rotter +56 more
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BMC Genomics, 2023 Objectives We performed comprehensive association analyses of common high-confidence gnomAD-reported copy number deletions (CNDs) with 60 quantitative traits from UK10K consortium WGS data.
Sejoon Lee, Jinho Kim, Jung Hun Ohn
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Psoriasis: An Immunogenetic Perspective
Global Medical Genetics, 2022 Psoriasis is an erythematous-squamous dermatosis with a polygenic inheritance history. Both environmental and genetic factors play a role in the etiology of the disease.
Ayca Kocaaga, Mustafa Kocaaga
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On deformation cohomology of compatible Hom-associative algebras [PDF]
arXiv, 2022 In this paper, we consider compatible Hom-associative algebras as a twisted version of compatible associative algebras. Compatible Hom-associative algebras are characterized as Maurer-Cartan elements in a suitable bidifferential graded Lie algebra. We also define a cohomology theory for compatible Hom-associative algebras generalizing the classical ...
arxiv
Genomic characterization and phylogenetic analysis of Salmonella enterica serovar Javiana [PDF]
PeerJ, 2020 Salmonella enterica serovar Javiana is the fourth most reported serovar of laboratory-confirmed human Salmonella infections in the U.S. and in Tennessee (TN). Although Salmonella ser.
Lauren K. Hudson +7 more
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Classification, Derivations and Centroids of Low-Dimensional Real Trialgebras [PDF]
arXiv, 2023 In this paper we study the structure and the algebraic varieties of associative trialgebras. We provide a classification of n-dimensional associative trialgebras for n $\leq$ 4. Using the classification result of associative trialgebras, we describe the derivations and centroids of low-dimensional associative trialgebras.
arxiv
Genome-wide Association Studies
, 2013 Genome-wide association studies (GWAS) are a powerful hypothesis-free tool for the dissection of susceptibility to common heritable human diseases, including osteoporosis. To date, more than 10,000 loci for common human diseases and traits have been identified by GWAS; and it is hard to think of a methodological breakthrough in recent times that has ...
Duncan, Emma, Brown, Matthew
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Genome-wide Association Study for AKI
Kidney360, 2023 Key Points Two genetic variants in the DISP1-TLR5 gene locus were associated with risk of AKI.DISP1 and TLR5 were differentially regulated in kidney biopsy tissue from patients with AKI compared with no AKI. Background
Pavan K. Bhatraju +24 more
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