Results 221 to 230 of about 115,431 (259)

Using PLINK for Genome-Wide Association Studies (GWAS) and Data Analysis

2013
Within this chapter we introduce the basic PLINK functions for reading in data, applying quality control, and running association analyses. Three worked examples are provided to illustrate: data management and assessment of population substructure, association analysis of a quantitative trait, and qualitative or case-control association analyses.
Rentería, Miguel E., Cortes, Adrian, Medland, Sarah E.   +2 more
openaire   +6 more sources

Genome-wide association study (GWAS) of resistance to head smut in maize

Plant Science, 2012
Head smut, caused by the fungus Sphacelotheca reiliana (Kühn) Clint, is a devastating global disease in maize, leading to severe quality and yield loss each year. The present study is the first to conduct a genome-wide association study (GWAS) of head smut resistance using the Illumina MaizeSNP50 array.
Ming, Wang, Jianbing, Yan, Jiuran, Zhao, Wei, Song, Xiaobo, Zhang, Yannong, Xiao, Yonglian, Zheng   +6 more
openaire   +2 more sources

Overview of Statistical Methods for Genome-Wide Association Studies (GWAS)

2013
This chapter provides an overview of statistical methods for genome-wide association studies (GWAS) in animals, plants, and humans. The simplest form of GWAS, a marker-by-marker analysis, is illustrated with a simple example. The problem of selecting a significance threshold that accounts for the large amount of multiple testing that occurs in GWAS is ...
openaire   +4 more sources

Genome‐wide association studies (GWAS): impact on elucidating the aetiology of diabetes

Diabetes/Metabolism Research and Reviews, 2011
AbstractIt has proven to be challenging to isolate the genes underlying the genetic components conferring susceptibility to type 1 and type 2 diabetes. Unlike previous approaches, ‘genome‐wide association studies’ have extensively delivered on the promise of uncovering genetic determinants of complex diseases, with a number of novel disease‐associated ...
Hakon, Hakonarson, Struan F A, Grant
openaire   +2 more sources

A Genome-Wide Association Study (GWAS) of Takotsubo syndrome

European Heart Journal
Abstract Background Takotsubo syndrome (TS) is an acute cardiac condition of unknown etiology characterized by transient regional systolic dysfunction of the left and/or right ventricle. Several studies have suggested the importance of genetics; however, studies are limited and have presented ...
H F K Hakansson, P Tornvall
openaire   +1 more source

GWA-Portal: Genome-Wide Association Studies Made Easy

2018
Genome-wide association studies (GWAS) are an effective method for investigating the genetics of natural phenotypic variation in many different model organisms.Here we present GWA-Portal, an interactive web application that enables researchers to upload their phenotypes and easily carry out GWAS directly in the browser.
openaire   +2 more sources

Genome-Wide Association Study (GWAS)

2013
Elizabeth Galik, Shin Fukudo, Yukari Tanaka, Yori Gidron, Tavis S. Campbell, Jillian A. Johnson, Kristin A. Zernicke, Jennifer Pellowski, Luis I. García, Jason W. Mitchell, Jennifer Toller Erausquin, Rany M. Salem, Laura Rodriguez-Murillo, Ornit Chiba-Falek, Rong Jiang, Rong Jiang, Tavis S. Campbell, Jillian A. Johnson, Kristin A. Zernicke, J. Rick Turner, J. Rick Turner, Bonnie S. LeRoy, Julianne O’Daniel, Jeanette McCarthy, J. Rick Turner, Deidre Pereira, Timothy S. Sannes, Matthew A. Simonson, Jeanette McCarthy, J. Rick Turner, Laura Rodriguez-Murillo, Rany M. Salem, Phil Jones, Ivan Molton, Barbara Resnick, Barbara Resnick, Pearl Ghaemmaghami, Ulrike Ehlert, Yoshiyuki Takimoto, Mustafa al’Absi, Michael James Coons, Janine Sanchez, Michael James Coons, Michael James Coons, Luigi Meneghini, Yori Gidron, Alexandre Morizio, Simon Bacon, Jan R. Oyebode, Jan R. Oyebode, Yori Gidron, Jennifer Cumming, Giles M. Anderson   +52 more
openaire   +1 more source

Pro: Genome-Wide Association Studies (GWAS) in Asthma

American Journal of Respiratory and Critical Care Medicine, 2011
Scott T, Weiss, Edwin K, Silverman
openaire   +2 more sources

Genome-Wide Association Studies (GWAS) in Cereals

2021
Braulio J. Soto-Cerda, Akshaya Vasudevan, André Laroche, Raja Ragupathy   +3 more
openaire   +1 more source

GWAS Atlas: a curated resource of genome-wide variant-trait associations in plants and animals

Nucleic Acids Research, 2020
Dongmei Tian, Bixia Tang, Xufei Teng
exaly