Results 101 to 110 of about 4,323,813 (404)

Commentary: The Materials Project: A materials genome approach to accelerating materials innovation

open access: yes, 2013
Accelerating the discovery of advanced materials is essential for human welfare and sustainable, clean energy. In this paper, we introduce the Materials Project (www.materialsproject.org), a core program of the Materials Genome Initiative that uses high ...
Anubhav Jain   +10 more
semanticscholar   +1 more source

CADD: predicting the deleteriousness of variants throughout the human genome

open access: yesNucleic Acids Res., 2018
Combined Annotation-Dependent Depletion (CADD) is a widely used measure of variant deleteriousness that can effectively prioritize causal variants in genetic analyses, particularly highly penetrant contributors to severe Mendelian disorders.
Philipp Rentzsch   +4 more
semanticscholar   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Antarctic genomics [PDF]

open access: yesComparative and Functional Genomics, 2004
AbstractWith the development of genomic science and its battery of technologies, polar biology stands on the threshold of a revolution, one that will enable the investigation of important questions of unprecedented scope and with extraordinary depth and precision.
Clark, Melody S   +11 more
openaire   +2 more sources

Genome‐wide analysis of MYB family genes in Tripterygium wilfordii and their potential roles in terpenoid biosynthesis

open access: yesPlant Direct, 2022
Terpenoids are a class of significant bioactive components in the woody vine of Tripterygium wilfordii. Previous studies have shown that MYB transcription factors play important roles in plant secondary metabolism, growth, and developmental processes ...
Meng Xia   +6 more
doaj   +1 more source

The Coffee Genome Hub : [W185] [PDF]

open access: yes, 2014
The whole genome sequence of Coffea canephora, the perennial diploid species known as Robusta, has been recently obtained and portends to be published and released in the coming months.
Bocs, Stéphanie   +7 more
core  

Reference Based Genome Compression [PDF]

open access: yes, 2012
DNA sequencing technology has advanced to a point where storage is becoming the central bottleneck in the acquisition and mining of more data. Large amounts of data are vital for genomics research, and generic compression tools, while viable, cannot ...
Chern, Bobbie   +5 more
core   +2 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Comprehensive dissection of cis-regulatory elements in a 2.8 Mb topologically associated domain in six human cancers

open access: yesNature Communications
Cis-regulatory elements (CREs), such as enhancers and promoters, are fundamental regulators of gene expression and, across different cell types, the MYC locus utilizes a diverse regulatory architecture driven by multiple CREs.
Christina M. Caragine   +9 more
doaj   +1 more source

Genomic Characteristics of Bifidobacterium thermacidophilum Pig Isolates and Wild Boar Isolates Reveal the Unique Presence of a Putative Mobile Genetic Element with tetW for Pig Farm Isolates

open access: yesFrontiers in Microbiology, 2017
Genomic analysis was performed on seven strains of Bifidobacterium thermacidophilum, a Sus-associated Bifidobacterium. Three strains from the feces of domestic pigs (Sus scrofa domesticus) and four strains from the rectal feces of free-range Japanese ...
Sayaka Tsuchida   +6 more
doaj   +1 more source

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