Results 101 to 110 of about 3,618,170 (327)

Molecular Characterization of Dengue Virus Serotype 2 Cosmospolitan Genotype From 2015 Dengue Outbreak in Yunnan, China

Frontiers in Cellular and Infection Microbiology, 2018
In 2015, a dengue outbreak with 1,067 reported cases occurred in Xishuangbanna, a city in China that borders Burma and Laos. To characterize the virus, the complete genome sequence was obtained and phylogenetic, mutation, substitution and recombinant ...
Liming Jiang, Liming Jiang, Liming Jiang, Dehong Ma, Chao Ye, Chao Ye, Chao Ye, Chao Ye, Lihua Li, Xiaoman Li, Jiajia Yang, Jiajia Yang, Jiajia Yang, Yujiao Zhao, Yujiao Zhao, Yujiao Zhao, Juemin Xi, Juemin Xi, Juemin Xi, Xiaodan Wang, Xiaodan Wang, Xiaodan Wang, Junying Chen, Junying Chen, Junying Chen, Yue Pan, Yue Pan, Yue Pan, Xiyun Shan, Qiangming Sun, Qiangming Sun, Qiangming Sun   +31 more
doaj   +1 more source

Progressive Mauve: Multiple alignment of genomes with gene flux and rearrangement [PDF]

, 2009
Multiple genome alignment remains a challenging problem. Effects of recombination including rearrangement, segmental duplication, gain, and loss can create a mosaic pattern of homology even among closely related organisms.
Darling, Aaron E., Mau, Bob, Perna, Nicole T.   +2 more
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Multipartite viruses: A decentralized mode of functioning. [O.24] [PDF]

, 2015
Multipartite viruses are characterized by a genome composed of two or more nucleic acid segments, each encapsidated indivually. A classical view in virology assumes that the viral replication cycle occurs within individual cells, where the whole viral ...
Blanc, Stéphane, Gutiérrez, Serafin, Michalakis, Yannis, Sicard, Anne, Vernerey, Marie-Stéphanie   +4 more
core  

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

The Brassica genome

Frontiers in Plant Science, 2013
BRASSICA GENOME RESEARCH TOPIC Brassica species include important crops and provide unique materials for the study of genome evolution. These crops include six important vegetables and oilseed crops, which have been classically described by “U’s triangle’. The three diploid species B. rapa (A genome), B. nigra (B genome), and B.
Michael Freeling, Xiaowu Wang
openaire   +4 more sources

Roegneria yenchiana: A new species in the Triticeae (Poaceae) from the Hengduan Mountain region

Ecology and Evolution
Roegneria yenchiana sp. nov. (Triticeae) is a new species collected from Shangri‐la of Yunnan Province in China based on morphological, cytological, and molecular data. It is morphologically characterized by one spikelet per node, rectangular glums, awns
Li‐Na Sha, Xiao Liang, Xin‐Yi Zhang, Shan Gao, Yue Zhang, Yong‐Hong Zhou, Xing Fan   +6 more
doaj   +1 more source

Syngenta -- The Genome Giant? [PDF]

, 2005
Swiss gene giant Syngenta, the world's largest agrochemical corporation and third largest seed company (see tables) has applied for patents that could effectively allow the company to monopolize key gene sequences that are vital for rice breeding as well

core  

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source