Results 151 to 160 of about 3,743,554 (329)
CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane +12 morewiley +1 more sourceGenome-wide transcriptome profiling reveals molecular response pathways of Trichoderma harzianum in response to salt stress
Frontiers in MicrobiologyTrichoderma harzianum exhibits a strong biological control effect on many important plant pathogens, such as Fusarium oxysporum, Botrytis cinerea, and Meloidogyne. However, its biocontrol effectiveness is weakened or reduced under salt stress. The aim of Qihong Yang, Qihong Yang, Zhenchuan Mao, Yali Hao, Shijie Zheng, Jianlong Zhao, Yan Li, Yuhong Yang, Bingyan Xie, Bingyan Xie, Jian Ling, Yanlin Li, Yanlin Li +12 moredoaj +1 more sourceSupplementary Figure Legends from Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas
, 2023 Kai‐Oliver Henrich, Sebastian Bender, Maral Saadati, Daniel Dreidax, Moritz Gartlgruber, Chunxuan Shao, Carl Herrmann, Manuel Wiesenfarth, Martha Parzonka, Lea Wehrmann, Matthias Fischer, David J. Duffy, Emma Bell, Alica Torkov, Peter Schmezer, Christoph Plass, Thomas Höfer, Axel Benner, Stefan M. Pfister, Frank Westermann +19 moreopenalex +1 more sourceReduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh +8 morewiley +1 more sourceFirst fungal genome sequence from Africa: A preliminary analysis
South African Journal of Science, 2012 Some of the most significant breakthroughs in the biological sciences this century will emerge from the development of next generation sequencing technologies.Brenda Wingfield, Emma Steenkamp, Quentin Santana, Martin Coetzee, Stefan Bam, Irene Barnes, Chrizelle Beukes, Wai Yin Chan, Lieschen de Vos, Gerda Fourie, Melanie Friend, Thomas Gordon, Darryl Herron, Carson Holt, Ian Korf, Marija Kvas, Simon Martin, X. Mlonyeni, Kershney Naidoo, Mmatshepho Phasha, Alisa Postma, Oleg Reva, Heidi Roos, Melissa Simpson, Stephanie Slinski, Bernard Slippers, Rene Sutherland, Nicolaas van der Merwe, Magriet van der Nest, Stephanus Venter, Pieter Wilken, Mark Yandell, Renate Zipfel, Mike Wingfield +33 moredoaj Genome-Wide Binding Analysis of the Transcription Activator IDEAL PLANT ARCHITECTURE1 Reveals a Complex Network Regulating Rice Plant Architecture
, 2013 Zefu Lu, Hong Yu, Guosheng Xiong, Jing Wang, Yongqing Jiao, Guifu Liu, Yanhui Jing, Xiangbing Meng, Xingming Hu, Qian Qian, Xiangdong Fu, Yonghong Wang, Jiayang Li +12 moreopenalex +1 more sourceComplete genome sequences of microbacterium phages Tedro and BAjuniper
, 2023 Grace M. Anderson, Olivia E. Anderson, Clayton A. Bosma, Erin E. Brouwer, Kleyton M. DeGroot, Owen C. Hede, Daiki Jonouchi, Dylan J. Kirkeby, Jayron T. Klinghagen, Kate J. Kralik, Julia S. Kutz, Olivia F. Lott, Erika J. McKenney, Victoria L. Pavik, Cayli H. Penner, Garrett Raymon, Leah B. Rozeboom, Jett L. Skrien, Jessica K. Slight, Maegan J. Stokes, Jonas D. Tiensvold, Kyra J. Wajer, Alaena L. Trevino, Byron Noordewier, Sara S. Tolsma +24 moreopenalex +1 more sourceLiquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen +2 morewiley +1 more sourceRoegneria yenchiana: A new species in the Triticeae (Poaceae) from the Hengduan Mountain region
Ecology and EvolutionRoegneria yenchiana sp. nov. (Triticeae) is a new species collected from Shangri‐la of Yunnan Province in China based on morphological, cytological, and molecular data. It is morphologically characterized by one spikelet per node, rectangular glums, awns Li‐Na Sha, Xiao Liang, Xin‐Yi Zhang, Shan Gao, Yue Zhang, Yong‐Hong Zhou, Xing Fan +6 moredoaj +1 more source
