Results 11 to 20 of about 3,618,170 (327)
The era of reference genomes in conservation genomics [PDF]
Trends in Ecology & Evolution, 2022 Trends in Ecology & Evolution, 37 (3)
Formenti, Giulio +157 more
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Genomic markers on synthetic genomes [PDF]
Engineering in Life Sciences, 2021 AbstractGenome synthesis endows scientists the ability of de novo creating genomes absent in nature, by thorough redesigning DNA sequences and introducing numerous custom features. However, the genome synthesis is a labor‐ and time‐consuming work, and thus it is a challenge to verify and quantify the synthetic genome rapidly and precisely.
Ze-Xiong Xie +3 more
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Biobanks for genomics and genomics for biobanks [PDF]
Comparative and Functional Genomics, 2003 AbstractBiobanks include biological samples and attached databases. Human biobanks occur in research, technological development and medical activities. Population genomics is highly dependent on the availability of large biobanks. Ethical issues must be considered: protecting the rights of those people whose samples or data are in biobanks (information,
Anne Cambon-Thomsen +5 more
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GenomeFingerprinter and universal genome fingerprint analysis for systematic comparative genomics [PDF]
, 2013 How to compare whole genome sequences at large scale has not been achieved via conventional methods based on pair-wisely base-to-base comparison; nevertheless, no attention was paid to handle in-one-sitting a number of genomes crossing genetic category ...
Ai, Hannan +3 more
core +14 more sources
The genome of a songbird [PDF]
Nature, 2010 The zebra finch is an important model organism in several fields1,2 with unique relevance to human neuroscience3,4. Like other songbirds, the zebra finch communicates through learned vocalizations, an ability otherwise documented only in humans and a few other animals and lacking in the chicken5—the only bird with a sequenced genome until now6. Here we
Warren, Wesley C. +81 more
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Genome maps across 26 human populations reveal population-specific patterns of structural variation. [PDF]
, 2019 Large structural variants (SVs) in the human genome are difficult to detect and study by conventional sequencing technologies. With long-range genome analysis platforms, such as optical mapping, one can identify large SVs (>2 kb) across the genome in ...
Cao, Han +25 more
core +2 more sources
Formulating genome-scale kinetic models in the post-genome era. [PDF]
, 2008 The biological community is now awash in high-throughput data sets and is grappling with the challenge of integrating disparate data sets. Such integration has taken the form of statistical analysis of large data sets, or through the bottom-up ...
Jamshidi, Neema, Palsson, Bernhard Ø
core +2 more sources
Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin. [PDF]
, 2020 Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associated ...
Acevedo, David +7 more
core +2 more sources
BATCH-GE : batch analysis of next-generation sequencing data for genome editing assessment [PDF]
, 2016 Targeted mutagenesis by the CRISPR/Cas9 system is currently revolutionizing genetics. The ease of this technique has enabled genome engineering in-vitro and in a range of model organisms and has pushed experimental dimensions to unprecedented proportions.
Boel, Annekatrien +7 more
core +2 more sources
GenColors: Annotation and comparative genomics made easy [PDF]
, 2009 GenColors is a web-based software/database system initially aimed at an improved and accelerated annotation of prokaryotic genomes making extensive use of genome comparison (Romualdi et al., _Bioinformatics_ 2005; Romualdi et al., _Methods Mol.
Alessandro Romualdi +4 more
core +2 more sources