Results 11 to 20 of about 1,891,272 (273)

“Intestinimonas gabonensis” sp. nov., a new bacterium detected from a Gabonese stool specimen

open access: yesNew Microbes and New Infections, 2017
Detection of new bacteria becomes a major part of culturomics studies coupled with taxonogenomics. Using these strategies, we report here the main characteristics of a new species, “Intestinimonas gabonensis” strain GM5. It is a bacterium isolated from a
G. Mourembou   +6 more
doaj   +1 more source

A citizen science approach to monitoring of the Lion Panthera leo (Carnivora: Felidae) population in Niokolo-Koba National Park, Senegal

open access: yesJournal of Threatened Taxa, 2020
A voluntary citizen science approach was used in a pilot study of the relict population of the Critically Endangered western African Lion Panthera leo in Niokolo-Koba National Park (NKNP) in Senegal.
Dimitri Dagorne   +2 more
doaj   +1 more source

Genome-Wide Characterization of Host Transcriptional and Epigenetic Alterations During HIV Infection of T Lymphocytes

open access: yesFrontiers in Immunology, 2020
Background and methods: Host genomic alterations are closely related to dysfunction of CD4+ T lymphocytes in the HIV–host interplay. However, the roles of aberrant DNA methylation and gene expression in the response to HIV infection are not fully ...
Xi Zeng   +14 more
doaj   +1 more source

Genome-on-Diet: Taming Large-Scale Genomic Analyses via Sparsified Genomics [PDF]

open access: yesarXiv, 2022
Searching for similar genomic sequences is an essential and fundamental step in biomedical research and an overwhelming majority of genomic analyses. State-of-the-art computational methods performing such comparisons fail to cope with the exponential growth of genomic sequencing data.
arxiv  

siRNA Genome Screening Approaches to Therapeutic Drug Repositioning

open access: yesPharmaceuticals, 2013
Bridging high-throughput screening (HTS) with RNA interference (RNAi) has allowed for rapid discovery of the molecular basis of many diseases, and identification of potential pathways for developing safe and effective treatments.
Ralph A. Tripp   +3 more
doaj   +1 more source

Comparisons of Copy Number, Genomic Structure, and Conserved Motifs for α-Amylase Genes from Barley, Rice, and Wheat

open access: yesFrontiers in Plant Science, 2017
Barley is an important crop for the production of malt and beer. However, crops such as rice and wheat are rarely used for malting. α-amylase is the key enzyme that degrades starch during malting.
Qisen Zhang, Chengdao Li
doaj   +1 more source

Identification of Neuropeptides and Their Receptors in the Ectoparasitoid, Habrobracon hebetor

open access: yesFrontiers in Physiology, 2020
Neuropeptides are a group of signal molecules that regulate many physiological and behavioral processes by binding to corresponding receptors, most of which are G-protein-coupled receptors (GPCRs).
Kaili Yu   +9 more
doaj   +1 more source

Mutations of Novel Influenza A(H10N8) Virus in Chicken Eggs and MDCK Cells

open access: yesEmerging Infectious Diseases, 2014
The recent emergence of human infection with influenza A(H10N8) virus is an urgent public health concern. Genomic analysis showed that the virus was conserved in chicken eggs but presented substantial adaptive mutations in MDCK cells. Our results provide
Jian Yang   +9 more
doaj   +1 more source

Genome and Transcriptome Analyses Provide Insight Into the Omega-3 Long-Chain Polyunsaturated Fatty Acids Biosynthesis of Schizochytrium limacinum SR21

open access: yesFrontiers in Microbiology, 2020
Schizochytrium sp. is the best natural resource for omega-3 long-chain polyunsaturated fatty acids. We report a high-quality genome sequence of Schizochytrium limacinum SR21, which has a 63 Mb genome size, with a contig N50 of 2.67 Mb and 6,838 protein ...
Limin Liang   +9 more
doaj   +1 more source

The Impact of Genome Region of Difference 4 (RD4) on Mycobacterial Virulence and BCG Efficacy

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Comparative genome analyses have revealed a number of regions of difference (RD) among mycobacterial species. The functional consequences of most of these genome variations have not been studied.
Huanwei Ru   +10 more
doaj   +1 more source

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