Results 191 to 200 of about 3,409,680 (280)

Design and Application of a Genome-Wide SNP Array to Improve Conservation Outcomes in the Critically Endangered Southern Corroboree Frog. [PDF]

Mol Ecol Resour
Davidson MJ, Zenger KR, Keogh JS, Berger L, Skerratt LF, Kosch TA.   +5 more
europepmc   +1 more source

Fungal genomics [PDF]

Briefings in Functional Genomics, 2014
openaire   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Silver chimaera genome highlights lineage-specific sex chromosome and opsin gene evolution in holocephalans. [PDF]

DNA Res
Teramura A, Kadota M, Hirase S, Kuraku S, Kikuchi K.   +4 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Detection of Copy-Number Variations in CNS Tumours From Off-Target Reads of Hybrid-Capture Sequencing. [PDF]

Neuropathol Appl Neurobiol
Schnorrenberg J, Adrian YL, Schlathölter J, Ruckert C, Horvath J, Paulus W, Hasselblatt M, Thomas C.   +7 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

The mitochondrial genome characteristics of Coronocyclus coronatus (Looss, 1900) and comparative analysis with other strongylid nematodes. [PDF]

Parasitol Res
Hao Y, Xia Y, Ma L, Hao Z, Li B, Bu Y.
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Whole-genome simple sequence repeat development and genetic diversity analysis of sponge gourd (<i>Luffa cylindrica</i>). [PDF]

PeerJ
Cui R, Wang Z, Jia L, Miao Y, Yan C, Qian M, Shu Y, Zhang K.   +7 more
europepmc   +1 more source