Results 191 to 200 of about 2,869,706 (297)

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

Science, 2014
Ophir Shalem, Neville E. Sanjana, E. Hartenian, Xi Shi, David A. Scott, T. Mikkelsen, D. Heckl, B. Ebert, D. Root, John G Doench, Feng Zhang   +10 more
semanticscholar   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Whole genome sequence of a virulent and multidrug resistant Staphylococcus aureus strain MD02 isolated from a diabetic foot ulcer in Uganda. [PDF]

BMC Genom Data
Makeri D, Eilu E, Odoki M, Adebayo IA, Maghembe R, Abubakar M, Muhwezi R, Pius T, Dilli PP, Akinola SA, Agwu E.   +10 more
europepmc   +1 more source

Non-specific DNA Binding of Genome Regulating Proteins as a Biological Control Mechanism: 1. The lac Operon: Equilibrium Aspects [PDF]

, 1974
Peter H. von Hippel, Arnold Revzin, Carol A. Gross, Amy C. Wang   +3 more
openalex   +1 more source

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source

Near-complete reference genome assembly of Hoya carnosa. [PDF]

Sci Data
Kuang Y, Ouyang K, Xia M, Feng C, Kang M.   +4 more
europepmc   +1 more source

Studies on Mentha spicata. L. var crispa BENTH. (Genome analysis in Mentha. Part 1)

, 1960
Nagamori Ikeda, Seiroku Udo, Masaru Nakamura   +2 more
openalex   +2 more sources

Nasopharyngeal carcinoma. X. Presence of Epstein‐Barr genomes in separated epithelial cells of tumours in patients from Singapore, Tunisia and Kenya [PDF]

, 1975
Claude Des̀granges, H. Wolf, G de-Thé, K. Shanmugaratnam, N. Cammoun, R. Ellouz, George Klein, K. Lennert, Núbia Muñóz, Harald zur Hausen   +9 more
openalex   +1 more source

From FastQ Data to High‐Confidence Variant Calls: The Genome Analysis Toolkit Best Practices Pipeline

Current Protocols in Bioinformatics, 2013
G. Auwera, Mauricio O. Carneiro, C. Hartl, R. Poplin, G. Del Angel, Ami Levy-Moonshine, Tadeusz Jordan, Khalid Shakir, David Roazen, Joel Thibault, E. Banks, K. Garimella, D. Altshuler, S. Gabriel, M. DePristo   +14 more
semanticscholar   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source