Results 201 to 210 of about 4,660,063 (378)

Genome‐wide meta‐analysis of age‐related cognitive decline in population‐based older individuals [PDF]

, 2021
Vibha Acharya, Kang‐Hsien Fan, Beth E. Snitz, Mary Ganguli, Steven T. DeKosky, Oscar L. López, Eleanor Feingold, M. Ilyas Kamboh   +7 more
openalex   +1 more source

PLINK: a tool set for whole-genome association and population-based linkage analyses.

American Journal of Human Genetics, 2007
S. Purcell, B. Neale, K. Todd-Brown, L. Thomas, M. Ferreira, David Bender, J. Maller, P. Sklar, P. D. de Bakker, M. Daly, P. Sham   +10 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Recombination is required for efficient HIV-1 replication and the maintenance of viral genome integrity [PDF]

, 2018
Jonathan Rawson, Olga A. Nikolaitchik, Brandon F. Keele, Vinay K. Pathak, Wei-Shau Hu   +4 more
openalex   +1 more source

Cluster analysis and display of genome-wide expression patterns.

Proceedings of the National Academy of Sciences of the United States of America, 1998
M. Eisen, P. Spellman, P. Brown, D. Botstein   +3 more
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

STARR‐seq and UMI‐STARR‐seq: Assessing Enhancer Activities for Genome‐Wide‐, High‐, and Low‐Complexity Candidate Libraries

, 2019
Christoph Neumayr, Michaela Pagani, Alexander Stark, Cosmas D. Arnold   +3 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Recursive genome engineering decodes the evolutionary origin of an essential thymidylate kinase activity in Pseudomonas putida KT2440

, 2023
Nicolas T. Wirth, Katja Rohr, Antoine Danchin, Pablo I. Nikel   +3 more
openalex   +1 more source

Prokka: rapid prokaryotic genome annotation

Bioinform., 2014
Torsten Seemann
semanticscholar   +1 more source