Results 151 to 160 of about 1,550,449 (243)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Whole-Genome Analysis of a Historical Strain of Xanthomonas citri pv. citri Reveals Structural Variations. [PDF]

Int J Mol Sci
Li W, He L, Guan B, Zeng X, Zheng Z, He J.   +5 more
europepmc   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Spatial-temporal genome analysis and its application for the prediction of functional systems in bacteria and archaea. [PDF]

mBio
Karamycheva S, Wolf YI, Koonin EV, Makarova KS.   +3 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Molecular Epidemiology and Genetic Diversity of Influenza B Viruses Based on Whole-Genome Analysis in Japan and Myanmar, 2016-2020. [PDF]

Influenza Other Respir Viruses
Ichikawa Y, Saito R, Chon I, Phyu WW, Kyaw Y, Win SMK, Japanese Influenza Collaborative Study Group, Yoshioka S, Sun Y, Li J, Purnama TB, Wagatsuma K, Tamura T, Watanabe H, Aye MM, Setk S, Tin HH.   +16 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Genome analysis screening virulence genes for the altered pathogenicity of <i>Riemerella anatipestifer</i> in hens. [PDF]

Front Microbiol
Lv J, Chen H, Ma X, Cong Y, Song X, Li Y, Gao Y, Qin Z.   +7 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Full-genome analysis of emerging Coxsackievirus B4 genotype D strains associated with herpangina in eastern China. [PDF]

Microb Genom
Hu X, Sun Y, Xing B, Hu L, Liang Z, Fu J, Liang Y, Chen Y, Li Y, Chen L, Wang L, Wang W, Wang S, Lu Y.   +13 more
europepmc   +1 more source