Results 101 to 110 of about 300,948 (293)
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
MakeHub: Fully Automated Generation of UCSC Genome Browser Assembly Hubs
Genomics, Proteomics & Bioinformatics, 2019 Novel genomes are today often annotated by small consortia or individuals whose background is not from bioinformatics. This audience requires tools that are easy to use.
Katharina Jasmin Hoff
doaj
Saccharomyces Genome Database (SGD) provides secondary gene annotation using the Gene Ontology (GO) [PDF]
, 2002 Selina S. Dwight
openalex +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Three Rounds of Read Correction Significantly Improve Eukaryotic Protein Detection in ONT Reads
MicroorganismsBackground: Eukaryotes’ whole-genome sequencing is crucial for species identification, gene detection, and protein annotation. Oxford Nanopore Technology (ONT) is an affordable and rapid platform for sequencing eukaryotes; however, the relatively higher ...
Hussain A. Safar +2 more
doaj +1 more source
Full-length messenger RNA sequences greatly improve genome annotation [PDF]
, 2002 Brian J. Haas +8 more
openalex +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Data on the genome analysis of the wild edible mushroom, Russula griseocarnosa
Data in Brief, 2019 In the present article, we report data on the whole genome sequence of a wild edible and medicinal ectomycorrhizal fungus Russula griseocarnosa. The R. griseocarnosa genome consists of 64.81 Mb with a GC-pair content of 49.41%.
Fei Yu, Junfeng Liang
doaj
In Vivo Functional Proteomics: Mammalian Genome Annotation Using CD-Tagging [PDF]
, 2002 Jonathan W. Jarvik +6 more
openalex +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source