Results 81 to 90 of about 484,203 (191)
Annotation of 2,507 Saccharomyces cerevisiae genomes
Microbiology SpectrumSaccharomyces cerevisiae (baker’s yeast, budding yeast) is one of the most important model organisms for biological research and is a crucial microorganism in industry.
Meng Wang +8 more
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Predicting variant deleteriousness in non-human species: applying the CADD approach in mouse
BMC Bioinformatics, 2018 Background Predicting the deleteriousness of observed genomic variants has taken a step forward with the introduction of the Combined Annotation Dependent Depletion (CADD) approach, which trains a classifier on the wealth of available human genomic ...
Christian Groß +2 more
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Vgas: A Viral Genome Annotation System
Frontiers in Microbiology, 2019 The in-depth study of viral genomes is of great help in many aspects, especially in the treatment of human diseases caused by viral infections. With the rapid accumulation of viral sequencing data, improved, or alternative gene-finding systems have ...
Kai-Yue Zhang +5 more
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BMC Genomics, 2013 Background The green anole lizard, Anolis carolinensis, is a key species for both laboratory and field-based studies of evolutionary genetics, development, neurobiology, physiology, behavior, and ecology. As the first non-avian reptilian genome sequenced,
Eckalbar Walter L +9 more
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Prokka: rapid prokaryotic genome annotation [PDF]
Bioinformatics, 2014 Abstract Summary: The multiplex capability and high yield of current day DNA-sequencing instruments has made bacterial whole genome sequencing a routine affair. The subsequent de novo assembly of reads into contigs has been well addressed.
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Ten steps to get started in Genome Assembly and Annotation [version 1; referees: 2 approved]
F1000Research, 2018 As a part of the ELIXIR-EXCELERATE efforts in capacity building, we present here 10 steps to facilitate researchers getting started in genome assembly and genome annotation.
Victoria Dominguez Del Angel +15 more
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The Gene Ontology: enhancements for 2011 [PDF]
, 2012 The Gene Ontology (GO) (http://www.geneontology.org) is a community bioinformatics resource that represents gene product function through the use of structured, controlled vocabularies.
Chan, J. +3 more
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Annotated Bioinformatic Pipelines for Genome Assembly and Annotation of Mitochondrial Genomes
BIO-PROTOCOLMitochondrial genomes (mitogenomes) display relatively rapid mutation rates, low sequence recombination, high copy numbers, and maternal inheritance patterns, rendering them valuable blueprints for mapping lineages, uncovering historical migration patterns, understanding intraspecific population dynamics, and investigating how environmental pressures ...
Jessica Winn +2 more
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Genome cartography through domain annotation.
Genome biology, 2002 The evolutionary history of eukaryotic proteins involves rapid sequence divergence, addition and deletion of domains, and fusion and fission of genes. Although the protein repertoires of distantly related species differ greatly, their domain repertoires do not.
Ponting, C, Dickens, N
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Three Rounds of Read Correction Significantly Improve Eukaryotic Protein Detection in ONT Reads
MicroorganismsBackground: Eukaryotes’ whole-genome sequencing is crucial for species identification, gene detection, and protein annotation. Oxford Nanopore Technology (ONT) is an affordable and rapid platform for sequencing eukaryotes; however, the relatively higher ...
Hussain A. Safar +2 more
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