Results 211 to 220 of about 342,168 (262)

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

Advanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang, Chunhua Ren, Zhou Qin, Yimeng Cui, Bingbing Zhang, Peng Luo, Xuan Wang, Yaoqi Xie, Xin Zhang, Aifen Yan, Yang Zhang, Dingding Fan, Yang Liu, Wenjie Pan, Xiao Jiang, Lihong Yuan, Haipeng Qin, David M. Irwin, Chaoqun Hu, Yang Liu, Ting Chen   +20 more
wiley   +1 more source

Node features of chromosome structure networks and their connections to genome annotation. [PDF]

Comput Struct Biotechnol J
Xu Y, Das P, McCord RP, Shen T.
europepmc   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

MicroAnnot: A Dedicated Workflow for Accurate Microsporidian Genome Annotation. [PDF]

Int J Mol Sci
Tournayre J, Polonais V, Wawrzyniak I, Akossi RF, Parisot N, Lerat E, Delbac F, Souvignet P, Reichstadt M, Peyretaillade E.   +9 more
europepmc   +1 more source

The golden genome annotation of Ganoderma lingzhi reveals a more complex scenario of eukaryotic gene structure and transcription activity. [PDF]

BMC Biol
Wang L, Shi P, Ping Z, Huang Q, Jiang L, Ma N, Wang Q, Xu J, Zou Y, Huang Z.   +9 more
europepmc   +1 more source

RefSeq and the prokaryotic genome annotation pipeline in the age of metagenomes. [PDF]

Nucleic Acids Res
Haft DH, Badretdin A, Coulouris G, DiCuccio M, Durkin AS, Jovenitti E, Li W, Mersha M, O'Neill KR, Virothaisakun J, Thibaud-Nissen F.   +10 more
europepmc   +1 more source

Unraveling the chicken T cell repertoire with enhanced genome annotation. [PDF]

Front Immunol
Früh SP, Früh MA, Kaufer BB, Göbel TW.   +3 more
europepmc   +1 more source

Generative AI agents are transforming biology research: high resolution functional genome annotation for multiscale understanding of life. [PDF]

EBioMedicine
Harrer S, Rane RV, Speight RE.
europepmc   +1 more source

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Genome Annotation

2008
The dynamic structure and functions of genomes are being revealed simultaneously with the progress of genome analyses. Evidence indicating genome regional characteristics (genome annotations in a broad sense) provide the basis for further analyses. Target listing and screening can be effectively performed in silico using such data.
Hideya, Kawaji, Yoshihide, Hayashizaki
openaire   +3 more sources

Prokaryotic Genome Annotation

2021
In the last decade, the high-throughput and relatively low cost of short-read sequencing technologies have revolutionized prokaryotic genomics. This has led to an exponential increase in the number of bacterial and archaeal genome sequences available, as well as corresponding increase of genome assembly and annotation tools developed.
Jeffrey A, Kimbrel, Brendan M, Jeffrey, Christopher S, Ward   +2 more
openaire   +2 more sources