Results 211 to 220 of about 339,780 (261)
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2008
The dynamic structure and functions of genomes are being revealed simultaneously with the progress of genome analyses. Evidence indicating genome regional characteristics (genome annotations in a broad sense) provide the basis for further analyses. Target listing and screening can be effectively performed in silico using such data.
Hideya, Kawaji, Yoshihide, Hayashizaki
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The dynamic structure and functions of genomes are being revealed simultaneously with the progress of genome analyses. Evidence indicating genome regional characteristics (genome annotations in a broad sense) provide the basis for further analyses. Target listing and screening can be effectively performed in silico using such data.
Hideya, Kawaji, Yoshihide, Hayashizaki
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An Introduction to Genome Annotation
Current Protocols in Bioinformatics, 2015AbstractGenome projects have evolved from large international undertakings to tractable endeavors for a single lab. Accurate genome annotation is critical for successful genomic, genetic, and molecular biology experiments. These annotations can be generated using a number of approaches and available software tools.
Michael S, Campbell, Mark, Yandell
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2021
In the last decade, the high-throughput and relatively low cost of short-read sequencing technologies have revolutionized prokaryotic genomics. This has led to an exponential increase in the number of bacterial and archaeal genome sequences available, as well as corresponding increase of genome assembly and annotation tools developed.
Jeffrey A, Kimbrel +2 more
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In the last decade, the high-throughput and relatively low cost of short-read sequencing technologies have revolutionized prokaryotic genomics. This has led to an exponential increase in the number of bacterial and archaeal genome sequences available, as well as corresponding increase of genome assembly and annotation tools developed.
Jeffrey A, Kimbrel +2 more
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2016
The dynamic structure and functions of genomes are being revealed simultaneously with the progress of technologies and researches in genomics. Evidence indicating genome regional characteristics (genome annotations in a broad sense) provide the basis for further analyses.
Imad, Abugessaisa +2 more
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The dynamic structure and functions of genomes are being revealed simultaneously with the progress of technologies and researches in genomics. Evidence indicating genome regional characteristics (genome annotations in a broad sense) provide the basis for further analyses.
Imad, Abugessaisa +2 more
openaire +3 more sources
Current Opinion in Structural Biology, 2000
The Genome Annotation Assessment Project tested current methods of gene identification, including a critical assessment of the accuracy of different methods. Two new databases have provided new resources for gene annotation: these are the InterPro database of protein domains and motifs, and the Gene Ontology database for terms that describe the ...
S, Lewis, M, Ashburner, M G, Reese
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The Genome Annotation Assessment Project tested current methods of gene identification, including a critical assessment of the accuracy of different methods. Two new databases have provided new resources for gene annotation: these are the InterPro database of protein domains and motifs, and the Gene Ontology database for terms that describe the ...
S, Lewis, M, Ashburner, M G, Reese
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2018
The term "genome annotation" includes identification of protein-coding and noncoding sequences (e.g., repeats, rDNA, and ncRNA) in genome assemblies and attaching functional information (metadata) to these annotated features. Here, we describe the basic outline of fungal nuclear and mitochondrial genome annotation as performed at the US Department of ...
Sajeet, Haridas +2 more
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The term "genome annotation" includes identification of protein-coding and noncoding sequences (e.g., repeats, rDNA, and ncRNA) in genome assemblies and attaching functional information (metadata) to these annotated features. Here, we describe the basic outline of fungal nuclear and mitochondrial genome annotation as performed at the US Department of ...
Sajeet, Haridas +2 more
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Intrinsic errors in genome annotation
Trends in Genetics, 2001Genome sequencing is usually followed by routine annotation of protein function based on the assumption that similar sequences will have similar functions. Here, we introduce a simple calculation to estimate the magnitude of any possible annotation errors.
Damien P Devos, Alfonso Valencia
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2017
Newly sequenced genomes are being added to the tree of life at an unprecedented fast pace. Increasingly, such new genomes are phylogenetically close to previously sequenced and annotated genomes. In other cases, whole clades of closely related species or strains ought to be annotated simultaneously.
Stefanie, König +2 more
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Newly sequenced genomes are being added to the tree of life at an unprecedented fast pace. Increasingly, such new genomes are phylogenetically close to previously sequenced and annotated genomes. In other cases, whole clades of closely related species or strains ought to be annotated simultaneously.
Stefanie, König +2 more
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Annotating the Regulatory Genome
2010Determining the timing and molecular repertoire responsible for gene expression is fundamental to understanding a gene's function. Heritable differences in this character are increasingly regarded as explanatory for complex and common traits. For many known trait-predisposing genes, studies have sought to elucidate the associated logic behind gene ...
Stephen B, Montgomery +3 more
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