Results 201 to 210 of about 339,780 (261)

PneumoBrowse 2: an integrated visual platform for curated genome annotation and multiomics data analysis of Streptococcus pneumoniae. [PDF]

Nucleic Acids Res
Janssen AB, Gibson PS, Bravo AM, de Bakker V, Slager J, Veening JW.   +5 more
europepmc   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Node features of chromosome structure networks and their connections to genome annotation. [PDF]

Comput Struct Biotechnol J
Xu Y, Das P, McCord RP, Shen T.
europepmc   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

The golden genome annotation of Ganoderma lingzhi reveals a more complex scenario of eukaryotic gene structure and transcription activity. [PDF]

BMC Biol
Wang L, Shi P, Ping Z, Huang Q, Jiang L, Ma N, Wang Q, Xu J, Zou Y, Huang Z.   +9 more
europepmc   +1 more source

MicroAnnot: A Dedicated Workflow for Accurate Microsporidian Genome Annotation. [PDF]

Int J Mol Sci
Tournayre J, Polonais V, Wawrzyniak I, Akossi RF, Parisot N, Lerat E, Delbac F, Souvignet P, Reichstadt M, Peyretaillade E.   +9 more
europepmc   +1 more source

RefSeq and the prokaryotic genome annotation pipeline in the age of metagenomes. [PDF]

Nucleic Acids Res
Haft DH, Badretdin A, Coulouris G, DiCuccio M, Durkin AS, Jovenitti E, Li W, Mersha M, O'Neill KR, Virothaisakun J, Thibaud-Nissen F.   +10 more
europepmc   +1 more source

Unraveling the chicken T cell repertoire with enhanced genome annotation. [PDF]

Front Immunol
Früh SP, Früh MA, Kaufer BB, Göbel TW.   +3 more
europepmc   +1 more source

Generative AI agents are transforming biology research: high resolution functional genome annotation for multiscale understanding of life. [PDF]

EBioMedicine
Harrer S, Rane RV, Speight RE.
europepmc   +1 more source