Results 131 to 140 of about 2,597,991 (390)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

The genome sequence of pellitory-of-the-wall, Parietaria judaica L. (Urticaceae) [version 1; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research
We present a genome assembly from an individual Parietaria judaica (pellitory-of-the-wall; Tracheophyta; Magnoliopsida; Rosales; Urticaceae). The genome sequence is 538.7 megabases in span.
Maarten J. M. Christenhusz
doaj   +1 more source

Hi‐C scaffolded short‐ and long‐read genome assemblies of the California sea lion are broadly consistent for syntenic inference across 45 million years of evolution [PDF]

, 2021
Claire Peart, Christina L. Williams, Saurabh D. Pophaly, Benjamin A. Neely, Frances M. D. Gulland, David J. Adams, Bee Ling Ng, William Cheng, Michael E. Goebel, Olivier Fédrigo, Bettina Haase, Jacquelyn Mountcastle, Arkarachai Fungtammasan, Giulio Formenti, Joanna Collins, Jonathan Wood, Ying Sims, James Torrance, Alan Tracey, Kerstin Howe, Arang Rhie, Joseph I. Hoffman, Jeremy Johnson, Erich D. Jarvis, Matthew Breen, Jochen B. W. Wolf   +25 more
openalex   +1 more source

A high-quality apple genome assembly reveals the association of a retrotransposon and red fruit colour

Nature Communications, 2019
A complete and accurate genome sequence provides a fundamental tool for functional genomics and DNA-informed breeding. Here, we assemble a high-quality genome (contig N50 of 6.99 Mb) of the apple anther-derived homozygous line HFTH1, including 22 ...
Liyi Zhang, Jiang Hu, Xiaolei Han, Jingjing Li, Yuan Gao, C. Richards, Cai-xia Zhang, Yi Tian, Guiming Liu, Hera Gul, Dajiang Wang, Yu Tian, Chuanxin Yang, Minghui Meng, Gaopeng Yuan, Guodong Kang, Yonglong Wu, Kun Wang, Hengtao Zhang, Depeng Wang, P. Cong   +20 more
semanticscholar   +1 more source

Machine learning meets genome assembly

Briefings in Bioinformatics, 2018
AbstractMotivation: With the recent advances in DNA sequencing technologies, the study of the genetic composition of living organisms has become more accessible for researchers. Several advances have been achieved because of it, especially in the health sciences.
Padovani de Souza, Kleber, Carlos Setubal, João, Carlos Ponce de Leon F. de Carvalho, André, Oliveira, Guilherme, Chateau, Annie, Alves, Ronnie   +5 more
openaire   +4 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Chromosome-level genome assembly of black carp Mylopharyngodon piceus using Nanopore and Hi-C technologies

Scientific Data
Black carp (Mylopharyngodon piceus) is one of the “four famous domestic fishes” in China and an important economic fish in freshwater aquaculture. A high-quality genome is essential for advancing future biological research and breeding programs for this ...
Yuxuan Zhang, Yanwen Shao, Xudong Liu, Liang Zhong, Zhaoyan Zhong, Weiwei Zeng, Jiping Zhang, Wenlong Cai, Runsheng Li   +8 more
doaj   +1 more source

RNA Origami: Packaging a Segmented Genome in Orbivirus Assembly and Replication [PDF]

, 2021
Po-Yu Sung, Polly Roy
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

First telomere-to-telomere gapless assembly of the rice blast fungus Pyricularia oryzae

Scientific Data
Rice blast caused by Pyricularia oryzae (syn., Magnaporthe oryzae) was one of the most destructive diseases of rice throughout the world. Genome assembly was fundamental to genetic variation identification and critically impacted the understanding of its
Zhigang Li, Jun Yang, Xiaobei Ji, Jintao Liu, Changfa Yin, Vijai Bhadauria, Wensheng Zhao, You-Liang Peng   +7 more
doaj   +1 more source