Results 141 to 150 of about 4,666,723 (353)
Wellcome Open ResearchWe present a genome assembly of Veronica arvensis (wall speedwell; Streptophyta; Magnoliopsida; Lamiales; Plantaginaceae). The assembly consists of two haplotypes with total lengths of 368.79 megabases and 369.14 megabases.
Maarten J. M. Christenhusz
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Wellcome Open ResearchWe present a genome assembly of Betula pendula (Silver Birch; Streptophyta; Magnoliopsida; Fagales; Betulaceae). The assembly consists of two haplotypes with total lengths of 403.47 megabases and 411.74 megabases. Most of the haplotype 1 assembly (99.95%)
Maarten J. M. Christenhusz
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
A chromosome-level genome assembly of the disco clam, Ctenoides ales [PDF]
The bivalve subclass Pteriomorphia, which includes the economically important scallops, oysters, mussels, and ark clams, exhibits extreme ecological, morphological, and behavioral diversity.
Chudalayandi, Sivanandan +4 more
core
Nature Communications, 2019 A complete and accurate genome sequence provides a fundamental tool for functional genomics and DNA-informed breeding. Here, we assemble a high-quality genome (contig N50 of 6.99 Mb) of the apple anther-derived homozygous line HFTH1, including 22 ...
Li-Yi Zhang +20 more
semanticscholar +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Genome assembly and annotation
, 2022 genome assembly and ...
Hu Li (14170046) +8 more
core +1 more source
Wellcome Open ResearchWe present a genome assembly of Paulownia tomentosa (empress tree; Streptophyta; Magnoliopsida; Lamiales; Paulowniaceae). The assembly consists of two haplotypes with total lengths of 523.45 megabases and 513.68 megabases.
Ilia J. Leitch +2 more
doaj +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source