Results 121 to 130 of about 4,666,723 (353)
Building and Improving Reference Genome Assemblies [PDF]
Proceedings of the IEEE, 2017 A genome sequence assembly provides the foundation for studies of genotypic and phenotypic variation, genome structure, and evolution of the target organism. In the past four decades, there has been a surge of new sequencing technologies, and with these developments, computational scientists have developed new algorithms to improve genome assembly ...
Karyn Meltz Steinberg +6 more
openaire +3 more sources
Wellcome Open ResearchWe present a genome assembly of Bellis perennis (daisy; Streptophyta; Magnoliopsida; Asterales; Asteraceae). The assembly consists of two haplotypes with total lengths of 1,602.72 megabases and 1,503.20 megabases. Most of the haplotype 1 assembly (93.94%)
Michael F. Fay +2 more
doaj +1 more source
Improvement of the ayu (Plecoglossus altivelis) draft genome using Hi-C sequencing
BMC Research Notes, 2023 Objective The ayu or sweetfish Plecoglossus altivelis is ray-finned fish that is widely distributed in East Asia. The genome size of ayu was estimated at approximately 420 Mb.
Masatoshi Nakamoto, Takashi Sakamoto
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Genome assembly in E. nuttalli and comparison with public genome assembly.
, 2019 Genome assembly in E. nuttalli and comparison with public genome assembly.
Masayuki Tanaka (67900) +5 more
core +1 more source
Cranberry genome assembly statistics.
, 2022 Cranberry genome assembly statistics.
Bradley W. Abramson (12207009) +6 more
core +1 more source
Modernizing Reference Genome Assemblies
PLoS Biology, 2011 I have read the journal's policy and have the following conflicts: Paul Flicek is married to the deputy editor of PLoS Medicine, Melissa Norton. Evan Eichler is on the board of Pacific Biosciences. Support for this work came from the Intramural Research Program of the NIH, The National Library of Medicine, the European Molecular Biology ...
Church, Deanna M +38 more
openaire +5 more sources
BMC Genomics, 2019 Background The Mongolian gerbil (Meriones unguiculatus) has historically been used as a model organism for the auditory and visual systems, stroke/ischemia, epilepsy and aging related research since 1935 when laboratory gerbils were separated from their ...
Shifeng Cheng +9 more
doaj +1 more source
Fully phased human genome assembly without parental data using single-cell Strand-seq and long reads
Nature Biotechnology, 2020 Human genomes are typically assembled as consensus sequences that lack information on parental haplotypes. Here we describe a reference-free workflow for diploid de novo genome assembly that combines the chromosome-wide phasing and scaffolding ...
D. Porubsky +20 more
semanticscholar +1 more source