Results 101 to 110 of about 4,666,723 (353)

BOA: A partitioned view of genome assembly

iScience, 2022
Abstract De novo genome assembly is a fundamental problem in computational molecular biology that aims to reconstruct an unknown genome sequence from a set of short DNA sequences (or reads ) obtained from the genome.
Priyanka Ghosh, Xiaojing An, Patrick Keppler, Sureyya Emre Kurt, Ümit V. Çatalyürek, Sriram Krishnamoorthy, P. Sadayappan, Aravind Sukumaran Rajam, Ananth Kalyanaraman   +8 more
openaire   +3 more sources

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Addition of the microchromosome GGA25 to the chicken genome sequence assembly through radiation hybrid and genetic mapping [PDF]

, 2008
BACKGROUND: The publication of the first draft chicken sequence assembly became available in 2004 and was updated in 2006. However, this does not constitute a definitive and complete sequence of the chicken genome, since the microchromosomes are ...
Gourichon, David, Dawson, D.A., Deborah A. Dawson (7630160), Gourichon David, Burke, T., F. Vignoles (7630163), Pitel, F., Burke, Terry, Douaud, Marine,, Dawson Deborah A, Olivier Hanotte (89422), Vignoles, Florence, F., Hanotte, Olivier, M. Douaud (7630142), Gourichon, D., Vignoles, F., Morisson, Mireille, Morrison, M., F. Pitel (7630175), Fillon, Valérie, Vignoles Florence, Fillon, V., D. Gourichon (7630157), Gerus, M., M. Tixier-Boichard (7630169), Dawson, D., Bardes, Suzanne, Vignal Alain, Vignoles, Florence,, Fève Katia, Hanotte, O., Vignoles, Florence, S. Bardes (7630154), Bardes Suzanne, Douaud, M., Gerus Marie, Tixier-Boichard, M., K. Fève (7630145), Terry Burke (80052), Vignal, Alain, Bardes, S., Fève, Katia, Pitel, Frédérique, Dawson, Deborah A., Hanotte, Olivier H., Feve, Katia, K., V. Fillon (7630151), Morisson, M., Douaud, Marine, Morisson Mireille, Tixier-Boichard Michèle, Fillon Valérie, M. Gerus (7630148), Douaud Marine, Tixier-Boichard, Michèle, Douaud, Marine, M., Hanotte Olivier, A. Vignal (7630172), M. Morisson (7630166), Dawson, Deborah A, Pitel Frédérique, Gerus, Marie, Feve, Katia,, Vignal, A., Burke Terry, Fève, K.   +65 more
core   +2 more sources

GAML: Genome Assembly by Maximum Likelihood [PDF]

Algorithms for Molecular Biology, 2014
Resolution of repeats and scaffolding of shorter contigs are critical parts of genome assembly. Modern assemblers usually perform such steps by heuristics, often tailored to a particular technology for producing paired or long reads.We propose a new framework that allows systematic combination of diverse sequencing datasets into a single assembly.
Vladimír Boza, Brona Brejová, Tomás Vinar   +2 more
openaire   +3 more sources

The genome sequence of the Amphibious Bistort, Persicaria amphibia (L.) Delarbre (Caryophyllales: Polygonaceae) [version 1; peer review: 2 approved]

Wellcome Open Research
We present a genome assembly of Persicaria amphibia (Amphibious Bistort; Streptophyta; Magnoliopsida; Caryophyllales; Polygonaceae). The assembly consists of two haplotypes with total lengths of 1,825.68 megabases and 1,833.10 megabases.
Markus Ruhsam
doaj   +1 more source

A chromosome-level genome assembly for the Pacific oyster Crassostrea gigas

bioRxiv, 2020
The Pacific oyster (Crassostrea gigas) is a marine bivalve species with vital roles in coastal ecosystems and aquaculture globally. While extensive genomic tools are available for C. gigas, highly contiguous reference genomes are required to support both
C. Peñaloza, A. P. Gutierrez, L. Eory, Shan Wang, X. Guo, Alan L. Archibald, Tim P. Bean, R. Houston   +7 more
semanticscholar   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

transcriptome-and-genome-assembly: transcriptome-and-genome-assembly Version 1.0.0

, 2015
<p><a href="url"></a></p> <p>Scripts to assemble de novo transcriptomes and genomes.</p> <a class="anchor" href="#pipelines-with-sample-data-sets"><span class="octicon octicon-link"></span></a ...
Jennifer Shelton
core   +1 more source

A maximum likelihood approach to genome assembly [PDF]

, 2022
De novo genome assembly is the bioinformatics' problem to reconstruct the original molecule from its sub-sequences, with no previous knowledge on DNA. Inspired by the maximum likelihood approach, recently a new experimental approach was developed.
Baruzzo, Giacomo
core  

The genome sequence of Bird’s-foot, Ornithopus perpusillus L. (Fabales: Fabaceae) [version 1; peer review: 2 approved]

Wellcome Open Research
We present a genome assembly of Ornithopus perpusillus (Bird’s-foot; Streptophyta; Magnoliopsida; Fabales; Fabaceae). The assembly consists of two haplotypes with total lengths of 528.92 megabases and 473.72 megabases.
Michael F. Fay, Ilia J. Leitch, Maarten J. M. Christenhusz, Maria S. Vorontsova   +3 more
doaj   +1 more source