Results 81 to 90 of about 2,481,819 (312)

Capture of complete ciliate chromosomes in single sequencing reads reveals widespread chromosome isoforms

BMC Genomics, 2019
Background Whole-genome shotgun sequencing, which stitches together millions of short sequencing reads into a single genome, ushered in the era of modern genomics and led to a rapid expansion of the number of genome sequences available.
Kelsi A. Lindblad, Jananan S. Pathmanathan, Sandrine Moreira, John R. Bracht, Robert P. Sebra, Elizabeth R. Hutton, Laura F. Landweber   +6 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

ling-lyang/Leptodactylus-fuscus-genome: de novo genome assembly of Leptodactylus fuscus

, 2021
A de novo genome assembly of Leptodactylus ...
Lu "Ling" Yang
core   +1 more source

A chromosome-level genome assembly of tomato pinworm, Tuta absoluta

Scientific Data, 2023
The tomato pinworm, Tuta absoluta, or Phthorimaea absouta, is native to South America, but quickly spread to other regions of world, including Europe, Africa, and Asia, devastating to global tomato production.
Ying Liu, Xi Chen, Yanqiong Yin, Xiaowei Li, Kang He, Xueqing Zhao, Xiangyong Li, Xiyan Luo, Yang Mei, Zuoqi Wang, Runguo Shu, Ziqi Cheng, Kifle Gebreegziabiher Gebretsadik, Chen Luo, Ran Wang, Yaobin Lv, Aidong Chen, Fei Li   +17 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Quality data of whole-genome-sequence and assembly.

, 2020
Quality data of whole-genome-sequence and assembly.
Fumihiko Takeuchi (118220), Hisako Kyan (4922593), Akinori Yamano (8394009), Tatsunori Masatani (497109), Toshihiro Matsui (1917), Takaya Sakura (2016025), Mami Murakami (791941), Kisaburo Nagamune (180747), Ryuma Matsubara (813362), Junpei Fukumoto (8394006), Michiru Tahara (180743), Motomichi Matsuzaki (78878), Tomohide Matsuo (46062), Yasuhiro Takashima (188527)   +13 more
core   +1 more source

A maximum likelihood approach to genome assembly [PDF]

, 2022
De novo genome assembly is the bioinformatics' problem to reconstruct the original molecule from its sub-sequences, with no previous knowledge on DNA. Inspired by the maximum likelihood approach, recently a new experimental approach was developed.
Baruzzo, Giacomo
core  

gymnome-assembly: OpenAI Environments for Genome Assembly

, 2023
<p>OpenAI Environments to simulate genome assemblies. These environments are described in the paper "<em>A step toward a reinforcement learning de novo genome assembler</em>".
kriowloo
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Transcriptome and methylome profiling reveals relics of genome dominance in the mesopolyploid Brassica oleracea [PDF]

, 2014
Background: Brassica oleracea is a valuable vegetable species that has contributed to human health and nutrition for hundreds of years and comprises multiple distinct cultivar groups with diverse morphological and phytochemical attributes.
John Nixon, Denoeud, France, Parkin, Isobel AP, Annaliese S Mason, Town, Chris D, Huebert, Terry, Sharpe, Andrew G., Manoli, Sahana, Bancroft, Ian, France Denoeud, Sateesh Kagale, Just, J\ue9r\ue9my, Robinson, Stephen J., Vivek Krishnakumar, Clarke, Carling, Links, Matthew G., Robinson, Stephen J, Wayne E Clarke, Guy Barker, Barker, Guy C., Shelby L Bidwell, Koh, Chushin, Moore, Jonathan D., Sharpe, Andrew G, Jacqueline Batley, Edwards, David, Clarke, Wayne E., Harry Belcram, Jérémy Just, Bidwell, Shelby L., Just, Jérémy, Carling Clarke, Jonathan Moore, Edwards, Dave, Nelson, Matthew N, David Edwards, Batley, Jacqueline, Matthew N Nelson, Stephen J Robinson, Sahana Manoli, Bidwell, Shelby L, Pires, J. Chris, Parkin, Isobel A. P., Chalhoub, Boulos, Terry Huebert, Andrew H Paterson, Krishnakumar, Vivek, Belcram, Harry, H., Walley, Peter G, Bender, Tricia, Tricia Bender, Town, Chris D., Nelson, Matthew N., King, Graham, J Pires, Mason, Annaliese S., Graham King, Pires, Chris J., Matthew G Links, Nixon, John, Chris D Town, Boulos Chalhoub, Links, Matthew G, Ian Bancroft, Belcram, Harry, Walley, Peter G., Mason, Annaliese S, Paterson, Andrew H, Walley, Peter Glen, Paterson, Andrew H., Moore, Jonathan, Barker, Guy, Kagale, Sateesh, Wang, Xiyin, Tang, Haibao, Pires, J Chris, Isobel AP Parkin, Pires, J., Andrew G Sharpe, Clarke, Wayne E, Xiyin Wang, Haibao Tang, Peter G Walley, Chushin Koh   +83 more
core   +1 more source