Results 91 to 100 of about 4,666,723 (353)

The genome sequence of wild privet, Ligustrum vulgare L. [version 1; peer review: 1 approved, 2 approved with reservations]

open access: yesWellcome Open Research
We present a genome assembly from a specimen of Ligustrum vulgare (wild privet; Streptophyta; Magnoliopsida; Lamiales; Oleaceae). The genome sequence has a total length of 1,384.00 megabases.
Michelle L. Hart   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Bioinformatics assembly and analysis and annotation of the Bacillus amyloliquefaciens strain 5036 genome [PDF]

open access: yes, 2010
Plants are essential for both human and animal life, several agricultural practices have been adopted or are being developed in order to improve crop production by preventing or mitigating effects of biotic and abiotic stresses faced by plants ...
Manzoor, Shahid
core   +1 more source

A chromosomal-scale genome assembly of modern cultivated hybrid sugarcane provides insights into origination and evolution

open access: yesNature Communications
Sugarcane is a vital crop with significant economic and industrial value. However, the cultivated sugarcane’s ultra-complex genome still needs to be resolved due to its high ploidy and extensive recombination between the two subgenomes. Here, we generate
Y. Bao   +24 more
semanticscholar   +1 more source

Assembly of long, error-prone reads using repeat graphs

open access: yesNature Biotechnology, 2018
Accurate genome assembly is hampered by repetitive regions. Although long single molecule sequencing reads are better able to resolve genomic repeats than short-read data, most long-read assembly algorithms do not provide the repeat characterization ...
M. Kolmogorov   +3 more
semanticscholar   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

The Atlas Genome Assembly System [PDF]

open access: yesGenome Research, 2004
Atlas is a suite of programs developed for assembly of genomes by a “combined approach” that uses DNA sequence reads from both BACs and whole-genome shotgun (WGS) libraries. The BAC clones afford advantages of localized assembly with reduced computational load, and provide a robust method for dealing with repeated sequences.
Paul, Havlak   +7 more
openaire   +2 more sources

Leveraging the Assembly of the Durum Wheat Genome cv. Svevo

open access: yes, 2017
Tetraploid wheat species, with his two wild and cultivated subspecies T. turgidum ssp. dicoccoides and ssp. durum, is a cornerstone of the wheat polyploidy complex.
The International Durum Wheat Sequencing Consortium   +3 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Tamias minimus reference genome Mitochondrial genome assembly

open access: yes, 2022
De novo assembly of the full mitochondrial genome for the Tamias minimus reference genome.
Nathanael Herrera (12525145)
core   +1 more source

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