Results 51 to 60 of about 2,597,991 (390)
REAPR: a universal tool for genome assembly evaluation. [PDF]
, 2013 Methods to reliably assess the accuracy of genome sequence data are lacking. Currently completeness is only described qualitatively and mis-assemblies are overlooked.
Berriman, Matthew +5 more
core +2 more sources
, 2021 Msc in Computational Biology of Universidad Politécnica de Madrid (UPM) Course: Genomics Data Analysis and Visualization Lesson 3: Genome assembly This tutorial is designed to introduce the tools, data types and workflow for bacterial genome assembly.
openaire +1 more source
A chromosome-level genome assembly of the Korean crossbred pig Nanchukmacdon (Sus scrofa)
Scientific Data, 2023 As plentiful high-quality genome assemblies have been accumulated, reference-guided genome assembly can be a good approach to reconstruct a high-quality assembly.
Daehong Kwon +12 more
doaj +1 more source
MitoZ: a toolkit for animal mitochondrial genome assembly, annotation and visualization
Nucleic Acids Research, 2019 Mitochondrial genome (mitogenome) plays important roles in evolutionary and ecological studies. It becomes routine to utilize multiple genes on mitogenome or the entire mitogenomes to investigate phylogeny and biodiversity of focal groups with the onset ...
Guanliang Meng +3 more
semanticscholar +1 more source
LongStitch: high-quality genome assembly correction and scaffolding using long reads
BMC Bioinformatics, 2021 Generating high-quality de novo genome assemblies is foundational to the genomics study of model and non-model organisms. In recent years, long-read sequencing has greatly benefited genome assembly and scaffolding, a process by which assembled sequences ...
Lauren Coombe +6 more
semanticscholar +1 more source
De novo assembly of the cattle reference genome with single-molecule sequencing. [PDF]
, 2020 BackgroundMajor advances in selection progress for cattle have been made following the introduction of genomic tools over the past 10-12 years. These tools depend upon the Bos taurus reference genome (UMD3.1.1), which was created using now-outdated ...
Bickhart, Derek M +32 more
core
Genome maps across 26 human populations reveal population-specific patterns of structural variation. [PDF]
, 2019 Large structural variants (SVs) in the human genome are difficult to detect and study by conventional sequencing technologies. With long-range genome analysis platforms, such as optical mapping, one can identify large SVs (>2 kb) across the genome in ...
Cao, Han +25 more
core +2 more sources
Modernizing Reference Genome Assemblies
PLoS Biology, 2011 I have read the journal's policy and have the following conflicts: Paul Flicek is married to the deputy editor of PLoS Medicine, Melissa Norton. Evan Eichler is on the board of Pacific Biosciences. Support for this work came from the Intramural Research Program of the NIH, The National Library of Medicine, the European Molecular Biology ...
Church, Deanna M +38 more
openaire +5 more sources
Nature Communications, 2020 Artificially improving traits of cultivated alfalfa (Medicago sativa L.), one of the most important forage crops, is challenging due to the lack of a reference genome and an efficient genome editing protocol, which mainly result from its autotetraploidy ...
Haitao Chen +23 more
semanticscholar +1 more source
Genome Biology and Evolution, 2021 Despite the progress made in DNA sequencing over the last decade, reconstructing telomere-to-telomere genome assemblies of large and repeat-rich eukaryotic genomes is still difficult.
D. Frei +10 more
semanticscholar +1 more source