Results 41 to 50 of about 452,095 (265)
Chromosome-level reference genome assembly for the mountain hare (Lepus timidus)
Peer Community JournalWe present here a high-quality genome assembly of a male mountain hare (Lepus timidus Linnaeus), from Ilomantsi, Eastern Finland, utilizing an isolated fibroblast cell line as the source for high quality DNA and RNA.
Fekete, Zsófia +5 more
doaj +1 more source
The independence of our genome assemblies [PDF]
Proceedings of the National Academy of Sciences, 2003 The characterization, analysis, and conclusions of Waterston et al. (1) with regard to our published work (2, 3) are incorrect. Celera was founded with the goal of applying the whole genome shotgun (WGS) strategy to assemble the sequence of the human genome as rapidly as possible to advance the field of genomics (4).
Mark D, Adams +4 more
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
BMC Genomics, 2019 Background The Mongolian gerbil (Meriones unguiculatus) has historically been used as a model organism for the auditory and visual systems, stroke/ischemia, epilepsy and aging related research since 1935 when laboratory gerbils were separated from their ...
Shifeng Cheng +9 more
doaj +1 more source
GAM: Genomic Assemblies Merger
EMBnet.journal, 2012 Motivations. In the last 3 years more than 20 assemblers have been proposed to tackle the hard task of assembling. Recent evaluation efforts (Assemblathon 1 and GAGE) demonstrated that none of these tools clearly outperforms the others. However, results clearly show that some assemblers performs better than others on specific regions and statistics ...
A Policriti +3 more
openaire +3 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
A reference quality, fully annotated diploid genome from a Saudi individual
Scientific DataWe have used multiple sequencing approaches to sequence the genome of a volunteer from Saudi Arabia. We use the resulting data to generate a de novo assembly of the genome, and use different computational approaches to refine the assembly.
Maxat Kulmanov +19 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Improvement of the ayu (Plecoglossus altivelis) draft genome using Hi-C sequencing
BMC Research Notes, 2023 Objective The ayu or sweetfish Plecoglossus altivelis is ray-finned fish that is widely distributed in East Asia. The genome size of ayu was estimated at approximately 420 Mb.
Masatoshi Nakamoto, Takashi Sakamoto
doaj +1 more source
BOA: A partitioned view of genome assembly
iScience, 2022 Abstract De novo genome assembly is a fundamental problem in computational molecular biology that aims to reconstruct an unknown genome sequence from a set of short DNA sequences (or reads ) obtained from the genome.
Priyanka Ghosh +8 more
openaire +3 more sources