Results 21 to 30 of about 2,481,819 (312)

HGGA: hierarchical guided genome assembler

open access: yesBMC Bioinformatics, 2022
AbstractBackgroundDe novogenome assembly typically produces a set of contigs instead of the complete genome. Thus additional data such as genetic linkage maps, optical maps, or Hi-C data is needed to resolve the complete structure of the genome. Most of the previous work uses the additional data to order and orient contigs.ResultsHere we introduce a ...
Riku Walve, Leena Salmela
openaire   +5 more sources

An improved genome of the model marine alga Ostreococcus tauri unfolds by assessing Illumina de novo assemblies [PDF]

open access: yes, 2014
Background: Cost effective next generation sequencing technologies now enable the production of genomic datasets for many novel planktonic eukaryotes, representing an understudied reservoir of genetic diversity. O.
Moreau, Hervé   +48 more
core   +1 more source

TlaskalV/Unicycler-genome-assembly: zenodo release

open access: yes, 2023
script which performs genome assembly of short ...
Vojtech Tlaskal
core   +1 more source

Assembler for de novo assembly of large genomes [PDF]

open access: yesProceedings of the National Academy of Sciences, 2013
Significance Assembling a large genome faces three challenges: assembly quality, computer memory requirement, and execution time. Our developed assembler, JR-Assembler, uses ( a ) a strategy that selects good seeds for contig construction, ( b
Te-Chin, Chu   +5 more
openaire   +2 more sources

AFLAP: assembly-free linkage analysis pipeline using k-mers from genome sequencing data

open access: yesGenome Biology, 2021
Our assembly-free linkage analysis pipeline (AFLAP) identifies segregating markers as k-mers in the raw reads without using a reference genome assembly for calling variants and provides genotype tables for the construction of unbiased, high-density ...
Kyle Fletcher   +5 more
doaj   +1 more source

A contiguous de novo genome assembly of sugar beet EL10 (Beta vulgaris L.) [PDF]

open access: yes, 2022
A contiguous assembly of the inbred ‘EL10’ sugar beet (Beta vulgaris ssp. vulgaris) genome was constructed using PacBio long-read sequencing, BioNano optical mapping, Hi-C scaffolding, and Illumina short-read error correction. The EL10.1 assembly was 540
Mutasa-Göttgens, E. S.   +27 more
core   +1 more source

Multi-Platform Next-Generation Sequencing of the Domestic Turkey (Meleagris gallopavo): Genome Assembly and Analysis [PDF]

open access: yes, 2010
A synergistic combination of two next-generation sequencing platforms with a detailed comparative BAC physical contig map provided a cost-effective assembly of the genome sequence of the domestic turkey (Meleagris gallopavo).
Kent M Reed   +405 more
core   +1 more source

Comparison of whole genome assemblies of the human genome [PDF]

open access: yesNucleic Acids Research, 2002
A fundamental problem in the human genome project is uncovering the correct assembly of the human genome. Many studies, including transcriptional analysis, SNP detection and characterization, gene finding and EST clustering, use genome assemblies as templates so it is important to determine the consistency among the various whole genome assemblies.
Eric C, Rouchka   +2 more
openaire   +2 more sources

Short read Illumina data for the de novo assembly of a non-model snail species transcriptome (Radix balthica, Basommatophora, Pulmonata), and a comparison of assembler performance [PDF]

open access: yes, 2011
Background: Until recently, read lengths on the Solexa/Illumina system were too short to reliably assemble transcriptomes without a reference sequence, especially for non-model organisms.
Wheat, Christopher W.   +10 more
core   +2 more sources

BACCardI - a tool for the validation of genomic assemblies, assisting genome finishing and intergenome comparison [PDF]

open access: yes, 2005
Bartels D, Kespohl S, Albaum S, et al. BACCardI - a tool for the validation of genomic assemblies, assisting genome finishing and intergenome comparison. Bioinformatics.
Kespohl, Sebastian   +12 more
core   +1 more source

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