Results 11 to 20 of about 4,666,723 (353)
BMC Genomics, 2009 Background We present here the assembly of the bovine genome. The assembly method combines the BAC plus WGS local assembly used for the rat and sea urchin with the whole genome shotgun (WGS) only assembly used for many other animal genomes including the ...
Sodergren Erica +15 more
doaj +4 more sources
Improvements in the sequencing and assembly of plant genomes [PDF]
GigaByte, 2021 Advances in DNA sequencing have made it easier to sequence and assemble plant genomes. Here, we extend an earlier study, and compare recent methods for long read sequencing and assembly.
Priyanka Sharma +11 more
doaj +4 more sources
The MaSuRCA genome assembler [PDF]
Bioinformatics, 2013 Abstract Motivation: Second-generation sequencing technologies produce high coverage of the genome by short reads at a low cost, which has prompted development of new assembly methods. In particular, multiple algorithms based on de Bruijn graphs have been shown to be effective for the assembly problem.
Aleksey V. Zimin +5 more
openaire +2 more sources
Comparative genome assembly [PDF]
Briefings in Bioinformatics, 2004 One of the most complex and computationally intensive tasks of genome sequence analysis is genome assembly. Even today, few centres have the resources, in both software and hardware, to assemble a genome from the thousands or millions of individual sequences generated in a whole-genome shotgun sequencing project.
Mihai Pop +3 more
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Whole-genome shotgun assembly and comparison of human genome assemblies [PDF]
Proceedings of the National Academy of Sciences, 2004 We report a whole-genome shotgun assembly (called WGSA) of the human genome generated at Celera in 2001. The Celera-generated shotgun data set consisted of 27 million sequencing reads organized in pairs by virtue of end-sequencing 2-kbp, 10-kbp, and 50-kbp inserts from shotgun clone libraries.
Istrail, S. +35 more
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Assembly: a resource for assembled genomes at NCBI [PDF]
Nucleic Acids Research, 2015 The NCBI Assembly database (www.ncbi.nlm.nih.gov/assembly/) provides stable accessioning and data tracking for genome assembly data. The model underlying the database can accommodate a range of assembly structures, including sets of unordered contig or scaffold sequences, bacterial genomes consisting of a single complete chromosome, or complex ...
Paul A. Kitts +13 more
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BlobTools: Interrogation of genome assemblies [PDF]
F1000Research, 2017 The goal of many genome sequencing projects is to provide a complete representation of a target genome (or genomes) as underpinning data for further analyses. However, it can be problematic to identify which sequences in an assembly truly derive from the target genome(s) and which are derived from associated microbiome or contaminant organisms.
Dominik R. Laetsch, Mark L. Blaxter
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npbhavya/microbial-genome-assembly:
, 2022 Scripts and code used for genome assembly of bacterial ...
Bhavya Papudeshi
core +1 more source
Maximum Likelihood Genome Assembly [PDF]
Journal of Computational Biology, 2009 Whole genome shotgun assembly is the process of taking many short sequenced segments (reads) and reconstructing the genome from which they originated. We demonstrate how the technique of bidirected network flow can be used to explicitly model the double-stranded nature of DNA for genome assembly.
Paul Medvedev, Michael Brudno
openaire +3 more sources