Results 11 to 20 of about 2,481,819 (312)
BMC Genomics, 2009 Background We present here the assembly of the bovine genome. The assembly method combines the BAC plus WGS local assembly used for the rat and sea urchin with the whole genome shotgun (WGS) only assembly used for many other animal genomes including the ...
Sodergren Erica +15 more
doaj +4 more sources
Improvements in the sequencing and assembly of plant genomes [PDF]
GigaByte, 2021 Advances in DNA sequencing have made it easier to sequence and assemble plant genomes. Here, we extend an earlier study, and compare recent methods for long read sequencing and assembly.
Priyanka Sharma +11 more
doaj +4 more sources
The MaSuRCA genome assembler [PDF]
Bioinformatics, 2013 Abstract Motivation: Second-generation sequencing technologies produce high coverage of the genome by short reads at a low cost, which has prompted development of new assembly methods. In particular, multiple algorithms based on de Bruijn graphs have been shown to be effective for the assembly problem.
Aleksey V. Zimin +5 more
openaire +2 more sources
Comparative genome assembly [PDF]
Briefings in Bioinformatics, 2004 One of the most complex and computationally intensive tasks of genome sequence analysis is genome assembly. Even today, few centres have the resources, in both software and hardware, to assemble a genome from the thousands or millions of individual sequences generated in a whole-genome shotgun sequencing project.
Mihai Pop +3 more
openaire +4 more sources
Whole-genome shotgun assembly and comparison of human genome assemblies [PDF]
Proceedings of the National Academy of Sciences, 2004 We report a whole-genome shotgun assembly (called WGSA) of the human genome generated at Celera in 2001. The Celera-generated shotgun data set consisted of 27 million sequencing reads organized in pairs by virtue of end-sequencing 2-kbp, 10-kbp, and 50-kbp inserts from shotgun clone libraries.
Istrail, S. +35 more
openaire +5 more sources
Assembly: a resource for assembled genomes at NCBI [PDF]
Nucleic Acids Research, 2015 The NCBI Assembly database (www.ncbi.nlm.nih.gov/assembly/) provides stable accessioning and data tracking for genome assembly data. The model underlying the database can accommodate a range of assembly structures, including sets of unordered contig or scaffold sequences, bacterial genomes consisting of a single complete chromosome, or complex ...
Paul A. Kitts +13 more
openaire +3 more sources
BlobTools: Interrogation of genome assemblies [PDF]
F1000Research, 2017 The goal of many genome sequencing projects is to provide a complete representation of a target genome (or genomes) as underpinning data for further analyses. However, it can be problematic to identify which sequences in an assembly truly derive from the target genome(s) and which are derived from associated microbiome or contaminant organisms.
Dominik R. Laetsch, Mark L. Blaxter
openaire +1 more source
Genome assembly of six polyploid potato genomes [PDF]
Scientific Data, 2020 AbstractGenome assembly of polyploid plant genomes is a laborious task as they contain more than two copies of the genome, are often highly heterozygous with a high level of repetitive DNA. Next Generation genome sequencing data representing one Chilean and five Peruvian polyploid potato (Solanum spp.) landrace genomes was used to construct genome ...
Maria Kyriakidou +4 more
openaire +3 more sources
npbhavya/microbial-genome-assembly:
, 2022 Scripts and code used for genome assembly of bacterial ...
Bhavya Papudeshi
core +1 more source
B-assembler: a circular bacterial genome assembler
BMC Genomics, 2022 Abstract Background Accurate bacteria genome de novo assembly is fundamental to understand the evolution and pathogenesis of new bacteria species. The advent and popularity of Third-Generation Sequencing (TGS) enables assembly of bacteria genomes at an unprecedented speed. However, most current
Fengyuan Huang +7 more
openaire +3 more sources