Results 51 to 60 of about 2,481,819 (312)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

A systematic comparison of chloroplast genome assembly tools

, 2022
Art. 254, 21 S.Background: Chloroplasts are intracellular organelles that enable plants to conduct photosynthesis. They arose through the symbiotic integration of a prokaryotic cell into an eukaryotic host cell and still contain their own genomes with ...
Freudenthal, J.A., Terhoeven, N., Korte, A., Pfaff, S., Ankenbrand, M.J., Förster, F.   +5 more
core   +1 more source

Chromosome-level reference genome assembly for the mountain hare (Lepus timidus)

Peer Community Journal
We present here a high-quality genome assembly of a male mountain hare (Lepus timidus Linnaeus), from Ilomantsi, Eastern Finland, utilizing an isolated fibroblast cell line as the source for high quality DNA and RNA.
Fekete, Zsófia, Absolon, Dominic E., Michell, Craig, Wood, Jonathan M. D., Goffart, Steffi, Pohjoismäki, Jaakko L. O.   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

The complexity of Rhipicephalus (Boophilus) microplus genome characterised through detailed analysis of two BAC clones [PDF]

, 2011
Background Rhipicephalus (Boophilus) microplus (Rmi) a major cattle ectoparasite and tick borne disease vector, impacts on animal welfare and industry productivity.
Peterson, D., Morgan Jess A T, Moolhuijzen, Paula M., Moolhuijzen, P.M., Dowd, S.E, Peterson, Daniel G., Bellgard, Matthew I., Bellgard Matthew I, Dowd Scot E, Bellgard, M.I., Appels, Rudi, Peterson Daniel G, Daniel G Peterson, Manuel Valle, Guerrero, F., Lew-Tabor, Ala E., Paula M Moolhuijzen, Valle, M.R., Appels Rudi, Moolhuijzen Paula M, Felix D Guerrero, Lew-Tabor, A.E., Lew-Tabor Ala E, Manuel Rodriguez Valle, Guerrero, F.D., Matthew I Bellgard, Lew-Tabor, A., Valle, Manuel Rodriguez, Guerrero Felix D, Moolhuijzen, Paula, Dowd, Scot E., Morgan, J.A.T., Dowd, S., Morgan, J., Valle, M., Bellgard, M., Scot E Dowd, Valle Manuel, Jess A T Morgan, Peterson, D.G., Appels, R., Rudi Appels, Ala E Lew-Tabor, Morgan, Jess A.T., Guerrero, Felix D.   +44 more
core   +2 more sources

The independence of our genome assemblies [PDF]

Proceedings of the National Academy of Sciences, 2003
The characterization, analysis, and conclusions of Waterston et al. (1) with regard to our published work (2, 3) are incorrect. Celera was founded with the goal of applying the whole genome shotgun (WGS) strategy to assemble the sequence of the human genome as rapidly as possible to advance the field of genomics (4).
Mark D, Adams, Granger G, Sutton, Hamilton O, Smith, Eugene W, Myers, J Craig, Venter   +4 more
openaire   +2 more sources

The genome sequence of wild privet, Ligustrum vulgare L. [version 1; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research
We present a genome assembly from a specimen of Ligustrum vulgare (wild privet; Streptophyta; Magnoliopsida; Lamiales; Oleaceae). The genome sequence has a total length of 1,384.00 megabases.
Michelle L. Hart, David Bell, Vladimir Krivtsov, Zoë A. Goodwin   +3 more
doaj   +1 more source

Enhancement of de novo sequencing, assembly and annotation of the Mongolian gerbil genome with transcriptome sequencing and assembly from several different tissues

BMC Genomics, 2019
Background The Mongolian gerbil (Meriones unguiculatus) has historically been used as a model organism for the auditory and visual systems, stroke/ischemia, epilepsy and aging related research since 1935 when laboratory gerbils were separated from their ...
Shifeng Cheng, Yuan Fu, Yaolei Zhang, Wenfei Xian, Hongli Wang, Benedikt Grothe, Xin Liu, Xun Xu, Achim Klug, Elizabeth A. McCullagh   +9 more
doaj   +1 more source

The genome sequence of the common frog, Rana temporaria Linnaeus 1758 [version 1; peer review: 2 approved]

Wellcome Open Research, 2021
We present a genome assembly from an individual female Rana temporaria (the common frog; Chordata; Amphibia; Anura; Ranidae). The genome sequence is 4.11 gigabases in span.
Jeffrey W. Streicher
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source