Results 261 to 270 of about 622,112 (341)

CRISPR-Mediated Genome Editing in Peanuts: Unlocking Trait Improvement for a Sustainable Future. [PDF]

Plants (Basel)
Han SJ, Chae J, Kim HJ, Kim JH, Chung YS, Karthik S, Heo JB.   +6 more
europepmc   +1 more source

Effects of Rna Purification Methods on Genome Editing in Olive Flounder and Turbot

Sishi Qin, Lijuan Wang, Zhihao Wu, Yinji Jin, Yansong Liu, Feng You, Xungang Tan   +6 more
openalex   +1 more source

BioCNTs Mediated Delivery of Systemically Mobile Small RNAs via Leaf Spray to Control Both Tomato DNA and RNA Viruses

Advanced Science, EarlyView.
A carbon nanotube‐based biopesticide system (BioCNTs) enables efficient delivery and systemic movement of RNAi molecules to control major tomato viruses. By integrating shRNA and tRNA‐like structures (TLS) with BioCNTs, this green and scalable approach achieves long‐term silencing and high antiviral efficacy through simple foliar spraying.
Xuedong Liu, Xiaofei Liang, Zipeng Cai, Zheng Liu, Xuefeng Wang, Changyong Zhou, Mengji Cao, Sijia Liu   +7 more
wiley   +1 more source

Directed evolution expands CRISPR-Cas12a genome-editing capacity. [PDF]

Nucleic Acids Res
Ma E, Chen K, Shi H, Wasko KM, Esain-Garcia I, Trinidad MI, Zhou K, Ye J, Doudna JA.   +8 more
europepmc   +1 more source

Protocol for genetic dissection of class switch recombination using genome-editing tools

Pengfei Dai, Tingting Liu, Dingpeng Yang, Yifeng Luo, Liu Daisy Liu, Xia Xie, Yafang Shang, Xiaojing Liu, Fei‐Long Meng   +8 more
openalex   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Emerging trends in prime editing for precision genome editing. [PDF]

Exp Mol Med
Lee J, Kweon J, Kim Y.
europepmc   +1 more source

Genome-wide CRISPR base-editing screening defines drug response networks in Leishmania

Jorge Arias del Angel, Fabian Link, Nicole Herrmann May, Ilkem Ekici, Konstantin Wawra, Simon Schwind, Samuel Zorn, Jennifer Haggarty, Stefan K. Weidt, Ryan Ritchie, Michael P. Barrett, Ger van Zandbergen, Tom Beneke   +12 more
openalex   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

CRISPR Genome Editing in Personalized Therapy for Oral and Maxillofacial Diseases: A Scoping Review. [PDF]

Biomedicines
Dziedzic A, Kubina R, Skonieczna M, Madej M, Fiegler-Rudol J, Abid M, Nadhim D, Tanasiewicz M.   +7 more
europepmc   +1 more source