Results 61 to 70 of about 1,792,457 (385)
Genome Editing for Improving Crop Nutrition
Frontiers in Genome Editing, 2022 Genome editing technologies, including CRISPR/Cas9 and TALEN, are excellent genetic modification techniques and are being proven to be powerful tools not only in the field of basic science but also in the field of crop breeding.
Ai Nagamine, H. Ezura
semanticscholar +1 more source
Viruses, 2022 Influenza A virus (IAV) causes a respiratory infection that affects millions of people of different age groups and can lead to acute respiratory distress syndrome.
Daria Prokhorova +5 more
doaj +1 more source
Is there any sense in antisense editing? [PDF]
Trends in Genetics 21, 544-7 (2005), 2005 A number of recent studies have hypothesized that sense-antisense RNA transcript pairs create dsRNA duplexes that undergo extensive A-to-I RNA editing. Here we studied human and mouse genomic antisense regions, and found that the editing level in these areas is negligible.
arxiv +1 more source
Nanoparticle Delivery of CRISPR/Cas9 for Genome Editing
Frontiers in Genetics, 2021 The emerging clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated system (Cas) gene-editing system represents a promising tool for genome manipulation. However, its low intracellular delivery efficiency severely compromises
Lijuan Duan +9 more
semanticscholar +1 more source
, 2023 Creative Biogene has the capacity to specifically modify microbial genomes in an efficient and precise way. With talented staffs, advanced technologies and state-of-the-art facilities, Creative Biogene provides microbial genome editing service, including traditional recombineering system, CRISPR/Cas 9 system and site-specific recombination system.
openaire +2 more sources
Editing the Mitochondrial Genome
New England Journal of Medicine, 2020 Mending Mitochondrial Mutation For most patients with mitochondrial disorders, most of which are caused by mutations in genes in the mitochondrial genome, only symptomatic treatment is available.
Maria Falkenberg, Michio Hirano
openaire +3 more sources
Breakthrough to genome editing [PDF]
Science, 2015 A, T, G, C: the alphabet code for the nucleotides that are the building blocks of life. Minor, but consequential, changes in this DNA coding can change gene function. Researchers have long sought better ways to edit the genetic code in cultured cells and laboratory organisms to silence, activate, or change targeted genes to gain a better ...
openaire +3 more sources
History of genome editing in yeast [PDF]
Yeast, 2018 AbstractFor thousands of years humans have used the budding yeast Saccharomyces cerevisiae for the production of bread and alcohol; however, in the last 30–40 years our understanding of the yeast biology has dramatically increased, enabling us to modify its genome. Although S.
Marcin G. Fraczek +2 more
openaire +3 more sources
An Investigation of Hepatitis B Virus Genome using Markov Models [PDF]
arXiv, 2023 The human genome encodes a family of editing enzymes known as APOBEC3 (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3). Several family members, such as APO-BEC3G, APOBEC3F, and APOBEC3H haplotype II, exhibit activity against viruses such as HIV. These enzymes induce C-to-U mutations in the negative strand of viral genomes, resulting
arxiv
Precision genome editing [PDF]
Nature Methods, 2018 A machine learning model predicts the genotype of CRISPR–Cas9 gene editing products, thereby enabling precise, template-free correction of disease-associated mutations.
openaire +3 more sources