Results 181 to 190 of about 526,413 (332)

Rapid, Scalable, and Combinatorial Genome Engineering by Markerless Enrichment and Recombination of Genetically Engineered Loci (MERGE) in Yeast

, 2022
Mudabir Abdullah, Brittany M. Greco, Jon M. Laurent, Riddhiman K. Garge, Daniel R. Boutz, Michelle Vandeloo, Edward M. Marcotte, Aashiq H. Kachroo   +7 more
openalex   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Engineering the Delivery System for CRISPR-Based Genome Editing

, 2018
Zachary Glass, Matthew Lee, Yamin Li, Qiaobing Xu   +3 more
openalex   +2 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Using Genome Engineering to Understand Huntington’s Disease [PDF]

, 2017
Barbara J. Bailus, Ningzhe Zhang, Lisa Ellerby   +2 more
openalex   +1 more source

Novel CRISPR-Associated Gene-Editing Systems Discovered in Metagenomic Samples Enable Efficient and Specific Genome Engineering

, 2023
Rebecca Lamothe, Meghan D. Storlie, Diego A. Espinosa, Rachel M. Rudlaff, Patrick Browne, Jason Liu, Andrés Rivas, Audra E. Devoto, Jennifer Oki, Ashcon Khoubyari, Daniela S. Aliaga Goltsman, Jyun‐Liang Lin, Cristina N. Butterfield, Christopher T. Brown, Brian C. Thomas, Gregory J. Cost   +15 more
openalex   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

The CRISPR/Cas9 System for Targeted Genome Engineering in Free-Living Fungi: Advances and Opportunities for Lichenized Fungi [PDF]

, 2019
Karthik Shanmugam, Sivaprakash Ramalingam, Gayathri Venkataraman, G. N. Hariharan   +3 more
openalex   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Genome Mining and Biological Engineering of Type III Borosins from Bacteria [PDF]

Kuang Xu, Sijia Guo, Wei Zhang, Zixin Deng, Qi Zhang, Wei Ding   +5 more
openalex   +1 more source