Results 31 to 40 of about 874,950 (354)
Transcription as a Threat to Genome Integrity [PDF]
, 2016 Genomes undergo different types of sporadic alterations, including DNA damage, point mutations, and genome rearrangements, that constitute the basis for evolution.
Aguilera López, Andrés +1 more
core +1 more source
GENESIS: genome evolution scenarios [PDF]
Bioinformatics, 2008 Abstract Summary: We implemented a software tool called GENESIS for three different genome rearrangement problems: Sorting a unichromosomal genome by weighted reversals and transpositions (SwRT), sorting a multichromosomal genome by reversals, translocations, fusions and fissions (SRTl), and sorting a multichromosomal genome by weighted ...
Simon, Gog +2 more
openaire +2 more sources
A Computational Method for the Rate Estimation of Evolutionary Transpositions
, 2015 Genome rearrangements are evolutionary events that shuffle genomic architectures. Most frequent genome rearrangements are reversals, translocations, fusions, and fissions.
J. Ma +8 more
core +1 more source
The Genome and Methylome of a Subsocial Small Carpenter Bee, Ceratina calcarata [PDF]
, 2016 Understanding the evolution of animal societies, considered to be a major transition in evolution, is a key topic in evolutionary biology. Recently, new gateways for understanding social evolution have opened up due to advances in genomics, allowing for ...
Glastad, Karl M. +3 more
core +2 more sources
Accumulation of genetic variants associated with immunity in the selective breeding of broilers
BMC Genetics, 2020 Background To satisfy an increasing demand for dietary protein, the poultry industry has employed genetic selection to increase the growth rate of broilers by over 400% in the past 50 years. Although modern broilers reach a marketable weight of ~ 2 kg in
Angela Zou +8 more
doaj +1 more source
Microbiome, 2018 Background The ability to efficiently characterize microbial communities from host individuals can be limited by co-amplification of host organellar sequences (mitochondrial and/or plastid), which share a common ancestor and thus sequence similarity with
Connor R. Fitzpatrick +7 more
doaj +1 more source
Germline ancestry influences the evolutionary disease course in lung adenocarcinomas
Evolutionary Applications, 2020 Precision medicine relies on targeting specific somatic alterations present in a patient's tumor. However, the extent to which germline ancestry may influence the somatic burden of disease has received little attention.
Alina Schenk +3 more
doaj +1 more source
The C-value enigma and timing of the Cambrian explosion
, 2008 The Cambrian explosion is a grand challenge to science today and involves multidisciplinary study. This event is generally believed as a result of genetic innovations, environmental factors and ecological interactions, even though there are many ...
Adami +29 more
core +1 more source
Deep cell phenotyping and spatial analysis of multiplexed imaging with TRACERx-PHLEX
Nature CommunicationsThe growing scale and dimensionality of multiplexed imaging require reproducible and comprehensive yet user-friendly computational pipelines. TRACERx-PHLEX performs deep learning-based cell segmentation (deep-imcyto), automated cell-type annotation ...
Alastair Magness +18 more
doaj +1 more source
Chemical genetics and strigolactone perception [version 1; referees: 2 approved]
F1000Research, 2017 Strigolactones (SLs) are a collection of related small molecules that act as hormones in plant growth and development. Intriguingly, SLs also act as ecological communicators between plants and mycorrhizal fungi and between host plants and a collection of
Shelley Lumba +2 more
doaj +1 more source