Results 91 to 100 of about 105,282 (228)

Gene Loss and Horizontal Gene Transfer Contributed to the Genome Evolution of the Extreme Acidophile “Ferrovum” [PDF]

open access: yes, 2016
Indexación: Web of Science. Scopus.Acid mine drainage (AMD), associated with active and abandoned mining sites, is a habitat for acidophilic microorganisms that gain energy from the oxidation of reduced sulfur compounds and ferrous iron and that thrive ...
Daniel, Rolf   +7 more
core   +2 more sources

Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance

open access: yesAdvanced Science, EarlyView.
In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei   +9 more
wiley   +1 more source

Identification, Cloning and Heterologous Expression of the Gene Cluster Directing RES-701-3, -4 Lasso Peptides Biosynthesis from a Marine Streptomyces Strain

open access: yesMarine Drugs, 2020
RES-701-3 and RES-701-4 are two class II lasso peptides originally identified in the fermentation broth of Streptomyces sp. RE-896, which have been described as selective endothelin type B receptor antagonists. These two lasso peptides only differ in the
Daniel Oves-Costales   +3 more
doaj   +1 more source

Mining the diatom genome for the mechanism of biosilicification [PDF]

open access: yesProceedings of the National Academy of Sciences, 2008
Ever since the invention of the microscope, scientists and laypeople alike have marveled at the intricate patterning of the silica within the diatom cell wall, termed the frustule (Fig. 1). There are well over 10,000 species of diatoms in marine and freshwaters, and each species has a unique wall morphology (1).
openaire   +2 more sources

Genomics Portals: integrative web-platform for mining genomics data [PDF]

open access: yesBMC Genomics, 2010
Abstract Background A large amount of experimental data generated by modern high-throughput technologies is available through various public repositories. Our knowledge about molecular interaction networks, functional biological pathways and transcriptional regulatory modules is rapidly expanding, and is being ...
Ghosh Krishnendu   +9 more
openaire   +3 more sources

Model‐Guided Systematic Metabolic Engineering for Enhanced Spinosad Biosynthesis in Saccharopolyspora spinosa NHF132

open access: yesAdvanced Science, EarlyView.
A genome‐scale model guided the systematic metabolic engineering of Saccharopolyspora spinosa, enabling a 5.5‐fold boost in the green bioinsecticide spinosad to 1.8 g L−1 and establishing an actinomycete framework for complex natural products overproduction.
Shuliu Wang   +9 more
wiley   +1 more source

Genome Mining Reveals Two Missing CrtP and AldH Enzymes in the C30 Carotenoid Biosynthesis Pathway in Planococcus faecalis AJ003T

open access: yesMolecules, 2020
Planococcus faecalis AJ003T produces glycosyl-4,4′-diaponeurosporen-4′-ol-4-oic acid as its main carotenoid. Five carotenoid pathway genes were presumed to be present in the genome of P.
Jun Ho Lee, Jin Won Kim, Pyung Cheon Lee
doaj   +1 more source

Genome-inspired molecular identification in organic matter via Raman spectroscopy

open access: yes, 2016
Rapid, non-destructive characterization of molecular level chemistry for organic matter (OM) is experimentally challenging. Raman spectroscopy is one of the most widely used techniques for non-destructive chemical characterization, although it currently ...
Bryndzia, L. Taras   +3 more
core   +1 more source

Cancer Biology of GSPT1: Mechanisms and Targeted Therapy Opportunities of Molecular Glue Degraders

open access: yesAdvanced Science, EarlyView.
This review systemically summarizes the structure, expression, regulatory networks, and isoform‐specific signaling of GSPT1 in cancers. According to the integration of GSPT1 targeted therapies, current challenges of GSPT1 targeted therapies are further analyzed, and provide therapeutic opportunities for the application of GSPT1 degraders in precision ...
Qiqi Lin   +8 more
wiley   +1 more source

WormBase - Nematode Biology and Genomes [PDF]

open access: yes, 2009
WormBase is the major public online database resource for the _Caenorhabditis_ research community. The database was developed primarily for the nematode _C.
Paul Davis, WormBase Consortium
core   +2 more sources

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