Results 101 to 110 of about 80,951 (303)

Genome Mining Reveals Two Missing CrtP and AldH Enzymes in the C30 Carotenoid Biosynthesis Pathway in Planococcus faecalis AJ003^T

Molecules, 2020
Planococcus faecalis AJ003T produces glycosyl-4,4′-diaponeurosporen-4′-ol-4-oic acid as its main carotenoid. Five carotenoid pathway genes were presumed to be present in the genome of P.
Jun Ho Lee, Jin Won Kim, Pyung Cheon Lee
doaj   +1 more source

Data mining parasite genomes

Parasitology, 2004
The term ‘data mining’ can be used to describe any process where useful information is extracted from data with a large background of ‘noise’. In the context of a genome project, several stages involve data mining. Amongst the sequence data, ‘signals’ need to be detected that indicate the presence of interesting features.
openaire   +2 more sources

Text-mining research in genomics [PDF]

, 2008
Biomedical text-mining have great promise to improve the usefulness of genomic researchers. The goal of text-mining is analyzed large collections of unstructured documents for the purposes of extracting interesting and non-trivial patterns of knowledge ...
Moya-Anegón, Félix, Gálvez, Carmen
core  

A realistic assessment of methods for extracting gene/protein interactions from free text [PDF]

, 2009
Background: The automated extraction of gene and/or protein interactions from the literature is one of the most important targets of biomedical text mining research.
Kabiljo, R., Clegg, AB, Renata Kabiljo, Shepherd, AJ, Kabiljo Renata, Clegg Andrew B, Andrew B Clegg, Shepherd Adrian J, Shepherd, Adrian J., Kabiljo, R, Clegg, A.B., Adrian J Shepherd   +11 more
core   +1 more source

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

Genome-wide analysis of the rice and arabidopsis () gene families and identification of wheat genes by EST data mining-2 [PDF]

, 2011
Able 2). Sequences were aligned using HMMERalign to maximize the eight-cysteine motif alignment, and manually refined. The conserved cysteine residues are black boxed and additional cysteine residues grey boxed.Copyright information:Taken from "Genome ...
Freddy Boutrot (76646), Nathalie Chantret (76647), Marie-Françoise Gautier (76648)   +2 more
core   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source

Genome-wide analysis of the rice and arabidopsis () gene families and identification of wheat genes by EST data mining-1 [PDF]

, 2011
Es were aligned using HMMERalign to maximize the eight-cysteine motif alignment, and manually refined. The conserved cysteine residues are black boxed and additional cysteine residues grey boxed.Copyright information:Taken from "Genome-wide analysis of ...
Freddy Boutrot (76646), Nathalie Chantret (76647), Marie-Françoise Gautier (76648)   +2 more
core   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

Advanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng, Wenxia Bu, Fengxu Wang, Yueyuan Jin, Rongzhu Liu, Rui Zhao, Xuehai Wang, Mengna Jiang, Jinping Shen, Xinhang Cheng, Zuming Chen, Li Zhu, Jinlong Li, Zhenzhong Ge, Shichen Miao, Haotian Xu, Xiaoyu Zhou, Dongming Wang, Xinyuan Zhao   +18 more
wiley   +1 more source

AGILE: an assembled genome mining pipeline

Bioinformatics, 2018
Abstract Summary A number of limiting factors mean that traditional genome annotation tools either fail or perform sub-optimally when trying to detect coding sequences in poor quality genome assemblies/genome reports.
Graham M. Hughes, Emma C. Teeling
openaire   +3 more sources