Results 101 to 110 of about 1,533,401 (302)

Genome Mining of Fungal Unique Trichodiene Synthase-like Sesquiterpene Synthases

Journal of Fungi
Sesquiterpenoids served as an important source for natural product drug discovery. Although genome mining approaches have revealed numerous novel sesquiterpenoids and biosynthetic enzymes, the comprehensive landscape of fungal sesquiterpene synthases ...
Zhanren Cong, Qiang Yin, Kunhong Tian, Njeru Joe Mukoma, Liming Ouyang, Tom Hsiang, Lixin Zhang, Lan Jiang, Xueting Liu   +8 more
doaj   +1 more source

AGILE: an assembled genome mining pipeline

Bioinformatics, 2018
Abstract Summary A number of limiting factors mean that traditional genome annotation tools either fail or perform sub-optimally when trying to detect coding sequences in poor quality genome assemblies/genome reports.
Graham M. Hughes, Emma C. Teeling
openaire   +4 more sources

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

Advanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su, Ye Tian, Fan Zhao, Jing Li, Suryaji Patil, Chunyu Zhu, Yujia Tian, Junrong Wang, Jiating Liu, Aoqi Xiang, Hua Guan, Lusha Zhang, Xiaochang Chen, Airong Qian, Qi Yu   +14 more
wiley   +1 more source

The Metabolic Potential of the Human Lung Microbiome

Microorganisms
The human lung microbiome remains largely underexplored, despite its potential implications in the pharmacokinetics of inhaled drugs and its involvement in lung diseases.
Florian Semmler, Matheus Regis Belisário-Ferrari, Maria Kulosa, Leonard Kaysser   +3 more
doaj   +1 more source

Mining the diatom genome for the mechanism of biosilicification [PDF]

Proceedings of the National Academy of Sciences, 2008
Ever since the invention of the microscope, scientists and laypeople alike have marveled at the intricate patterning of the silica within the diatom cell wall, termed the frustule (Fig. 1). There are well over 10,000 species of diatoms in marine and freshwaters, and each species has a unique wall morphology (1).
openaire   +2 more sources

Bioinformatics' approaches to detect genetic variation in whole genome sequencing data [PDF]

, 2010
Current genetic marker repositories are not sufficient or even are completely lacking for most farm animals. However, genetic markers are essential for the development of a research tool facilitating discovery of genetic factors that contribute to ...
Kerstens, H.H.D.
core  

Draft genome sequence of Salmonella enterica subsp. enterica Serovar gallinarum biovar pullorum strain FCAV198, a Brazilian chicken pathogen

, 2014
Salmonella enterica subsp. enterica serovar Gallinarum biovar Pullorum is a bird-restricted pathogen which causes pullorum disease. The strain FCAV198 was isolated from a pool of chicken ovaries in Brazil, and its genome may be helpful for studies ...
Almeida, Adriana Maria de, Salim, Anna, Varani, Alessandro de Mello, Oliveira, Guilherme Corrêa de, Araujo, Flavio Marcio Gomes, Leite, Laura Rabelo, Barrow, Paul A., Freitas Neto, Oliveiro Caetano de [UNESP], Varani, Alessandro de Mello [UNESP], Ribeiro, Simone Alves Mendes, Berchieri Junior, Angelo [UNESP], Batista, Diego Felipe Alves [UNESP], Almeida, Adriana Maria de [UNESP], Batista, Diego Felipe Alves, Berchieri Junior, Angelo, Freitas Neto, Oliveiro Caetano de   +15 more
core   +1 more source

Conditionally Significant eQTL and TWAS Analyses Identify MsRD26 as a Major Candidate Positive Regulator of Salt Tolerance in Medicago sativa L

Advanced Science, EarlyView.
Salt stress significantly impacts plant growth. Through population transcriptome, eQTL and TWAS analyses, we identified several candidate genes potentially associated with salt stress response. Functional assays suggested that some of these genes may contribute to salt tolerance.
Lin Chen, Yuqi Zhang, Xinyue Ma, Jinpeng Bi, Fei He, Li Zhao, Haiyue Lei, Zhengqin Xiao, Xue Wang, Tiejun Zhang, Ruicai Long, Junmei Kang, Qingchuan Yang   +12 more
wiley   +1 more source

Draft Genome Sequence of Marinobacter sp. Strain P4B1, an Electrogenic Perchlorate-Reducing Strain Isolated from a Long-Term Mixed Enrichment Culture of Marine Bacteria

, 2016
The perchlorate-reducing strain Marinobacter sp. strain P4B1 was isolated from a long-term perchlorate-degrading enrichment culture seeded with marine sediment. The draft genome of Marinobacter sp. P4B1 is comprised of the bacterial chromosome (3.60 Mbp,
Roberts, Deborah J., Xiao, Yeyuan, Fox, George E., Stepanov, Victor G., Lopez, April J.   +4 more
core   +1 more source

The CACTA transposon Bot1 played a major role in Brassica genome divergence and gene proliferation [PDF]

, 2008
We isolated and characterized a Brassica C genome-specific CACTA element, which was designated Bot1 (Brassica oleracea transposon 1). After analysing phylogenetic relationships, copy numbers and sequence similarity of Bot1 and Bot1 analogues in B ...
Joets, Johann, Moore, Jonathan D., Heslop-Harrison, J. (John), King , Graham J., Ryder, C. D., Heslop-Harrison, J. S., Joets, J., Bailey, John P., Moore, J., Ryder, Carol D., Bailey, J. P., Alix, K., Barker, G. C., King, G. J., Barker, Guy C., Alix, Karine   +15 more
core   +1 more source