Results 71 to 80 of about 1,533,401 (302)

Single‐Cell and Spatial Transcriptomics Unveil Key Regulators Governing Cell Differentiation for Schistosoma japonicum Sexual Development

Advanced Science, EarlyView.
Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu, Xiaoxu Wang, Shun Li, Xuxin Li, Pengfei Du, Yameng Zheng, Lu Liu, Yanyan Zhang, Omri Wurtzel, Guofeng Cheng   +9 more
wiley   +1 more source

Genomic and Physiological Characterization of Bacilli Isolated From Salt-Pans With Plant Growth Promoting Features

Frontiers in Microbiology, 2021
Massive application of chemical fertilizers and pesticides has been the main strategy used to cope with the rising crop demands in the last decades. The indiscriminate use of chemicals while providing a temporary solution to food demand has led to a ...
Claudia Petrillo, Stefany Castaldi, Mariamichela Lanzilli, Matteo Selci, Angelina Cordone, Donato Giovannelli, Donato Giovannelli, Donato Giovannelli, Donato Giovannelli, Donato Giovannelli, Rachele Isticato, Rachele Isticato   +11 more
doaj   +1 more source

Mining the chicken genome [PDF]

Genome Biology, 2002
The chicken EST repository gives access to a BLAST server dedicated to mining recently released sequence information from the chick large-scale expressed sequence tag (EST ...
openaire   +1 more source

Genome mining strategies for metallophore discovery

Current Opinion in Biotechnology, 2022
Many bacteria use small-molecule chelators called metallophores to acquire trace metals from their environment. These molecules play a central role in interactions between bacteria, plants, and animals. Hence, knowing their full diversity is key to combatting infectious diseases as well as harnessing beneficial microbial communities.
Reitz, Zachary L., Medema, Marnix H.
openaire   +3 more sources

Metagenomic Association Uncovers Host Genotype‐Structured Rhizobacterial Networks and Novel Taxa That Enhance Soybean Salt Tolerance

Advanced Science, EarlyView.
An STI‐guided metagenomic association framework links soybean salt‐tolerance phenotypes with rhizosphere microbiome composition and network organization in natural saline soils. The approach identifies candidate beneficial taxa, including Thalassospira xiamenensis, and provides an efficient strategy for mining stress‐protective microbes from native ...
Yu Luo, Feng‐Li Kang, Qi‐Min Li, Wei‐Cai Yang   +3 more
wiley   +1 more source

Leveraging the Assembly of the Durum Wheat Genome cv. Svevo

, 2017
Tetraploid wheat species, with his two wild and cultivated subspecies T. turgidum ssp. dicoccoides and ssp. durum, is a cornerstone of the wheat polyploidy complex.
The International Durum wheat Genome Sequencing Consortium, L. Cattivelli, M. Maccaferri   +2 more
core   +1 more source

Interpreting Microbial Biosynthesis in the Genomic Age: Biological and Practical Considerations

Marine Drugs, 2017
Genome mining has become an increasingly powerful, scalable, and economically accessible tool for the study of natural product biosynthesis and drug discovery.
Ian J. Miller, Marc G. Chevrette, Jason C. Kwan   +2 more
doaj   +1 more source

The Discovery of New Antilisterial Proteins From Paenibacillus polymyxa Kp10 via Genome Mining and Mass Spectrometry

Frontiers in Microbiology, 2020
The inhibitory properties of novel antimicrobial proteins against food-borne pathogens such as Listeria monocytogenes offer extensive benefits to the food and medical industries.
Nur Fadhilah Khairil Mokhtar, Nur Fadhilah Khairil Mokhtar, Amalia Mohd Hashim, Amalia Mohd Hashim, Irwan Hanish, Aisyah Zulkarnain, Raja Mohd Hafidz Raja Nhari, Asmahani Azira Abdul Sani, Sahar Abbasiliasi, Arbakariya Ariff, Shuhaimi Mustafa, Shuhaimi Mustafa, Shuhaimi Mustafa, Raha Abdul Rahim, Raha Abdul Rahim   +14 more
doaj   +1 more source

Integrated Metabolomic, Molecular Networking, and Genome Mining Analyses Uncover Novel Angucyclines From Streptomyces sp. RO-S4 Strain Isolated From Bejaia Bay, Algeria

Frontiers in Microbiology, 2022
Multi-omic approaches have recently made big strides toward the effective exploration of microorganisms, accelerating the discovery of new bioactive compounds. We combined metabolomic, molecular networking, and genomic-based approaches to investigate the
Rima Ouchene, Rima Ouchene, Didier Stien, Juliette Segret, Mouloud Kecha, Alice M. S. Rodrigues, Carole Veckerlé, Marcelino T. Suzuki   +7 more
doaj   +1 more source

Modulation of Lung Adenocarcinoma by Phosphorylated FOXN3‐Mediated Transcriptional Inactivation of p53

Advanced Science, EarlyView.
In non‐tumorous lung tissues, FOXN3 promotes the transcriptional activation of p53 by facilitating its recruitment to target promoters, thereby suppressing lung tumorigenesis through activation of the p53 signaling pathway. Conversely, in lung adenocarcinoma tissues, hyperphosphorylated FOXN3 dissociates from the promoters of p53‐responsive genes and ...
Jinjin Yu, Jingyu Yu, Suhui Wang, Xinghong Hu, Lele Jin, Nan Wu, Yuhan Ni, Xueying Zhang, Chengling Zhao, Jihong Zhou, Yong Zhang, Baofa Sun, Hongxing Zhang, Chunfu Zheng, Song Guo Zheng, Wei Li, Xinxing Zhu   +16 more
wiley   +1 more source