Results 61 to 70 of about 80,951 (303)

Genome Mining of Chryseobacterium proteolyticum for Keratinolytic Properties and Prospective Applications

Journal of Pure and Applied Microbiology
The manipulation of keratinolytic determinants provides an avenue for enhancing keratinase output, thereby facilitating the conversion of wasted chicken feathers into valuable products.
Lindelwa Mpaka, Nonso E. Nnolim, Uchechukwu U. Nwodo   +2 more
doaj   +1 more source

Expanding the Utility of Bioinformatic Data for the Full Stereostructural Assignments of Marinolides A and B, 24- and 26-Membered Macrolactones Produced by a Chemically Exceptional Marine-Derived Bacterium

Marine Drugs, 2023
Marinolides A and B, two new 24- and 26-membered bacterial macrolactones, were isolated from the marine-derived actinobacterium AJS-327 and their stereostructures initially assigned by bioinformatic data analysis.
Min Cheol Kim, Jaclyn M. Winter, Reiko Cullum, Alexander J. Smith, William Fenical   +4 more
doaj   +1 more source

Genome-wide analysis of the rice and arabidopsis () gene families and identification of wheat genes by EST data mining-0 [PDF]

, 2011
Copyright information:Taken from "Genome-wide analysis of the rice and arabidopsis () gene families and identification of wheat genes by EST data mining"http://www.biomedcentral.com/1471-2164/9/86BMC Genomics 2008;9():86-86.Published online 21 Feb ...
Freddy Boutrot (76646), Nathalie Chantret (76647), Marie-Françoise Gautier (76648)   +2 more
core   +1 more source

NPLinker eScience Workshop on Natural Product Genome & Metabolome Mining Materials [PDF]

, 2023
These materials were used as a part of the NPLinker eScience Workshop on Natural Product Genome & Metabolome Mining: https://www.wur.nl/en/research-results/chair-groups/plant-sciences/bioinformatics/teaching/nplinker_workshop.htm Most materials are ...
Tilmann Weber, Cunliang Geng, Marnix H. Medema, Barbara Terlouw, Justin J.J. van der Hooft, Corinna Brungs, Robin Schmid, Mitja M. Zdouc, Lindsay Caesar, Jorge C. Navarro-Muñoz, Tiago Leao, Paco Barona-Gómez   +11 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Discovery of fungal onoceroid triterpenoids through domainless enzyme-targeted global genome mining

Nature Communications
Genomics-guided methodologies have revolutionized the discovery of natural products. However, a major challenge in the field of genome mining is determining how to selectively extract biosynthetic gene clusters (BGCs) for untapped natural products from ...
Jia Tang, Yudai Matsuda
doaj   +1 more source

LabelBOT: A Human-in-the-Loop Classification Assistance in the BIIGLE Image Annotation Tool

IEEE Access
In marine science and engineering, growing volumes of imaging data are used in exploration and monitoring. The process of manual annotation of this data (i.e.
Gaby Kourie, Martin Zurowietz, Daniel Langenkamper, Davide Brembilla, Tim W. Nattkemper   +4 more
doaj   +1 more source

Mining the genome for lipid genes

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2014
Mining of the genome for lipid genes has since the early 1970s helped to shape our understanding of how triglycerides are packaged (in chylomicrons), repackaged (in very low density lipoproteins; VLDL), and hydrolyzed, and also how remnant and low-density lipoproteins (LDL) are cleared from the circulation.
Kuivenhoven, Jan Albert, Hegele, Robert A.   +1 more
openaire   +2 more sources

Genome sequence of Desulfosporosinus sp. OT, an acidophilic sulfate-reducing bacterium from copper mining waste in Norilsk, Northern Siberia [PDF]

, 2011
We have sequenced the genome of Desulfosporosinus sp. OT, a Gram-positive, acidophilic sulfate-reducing Firmicute isolated from copper tailing sediment in the Norilsk mining-smelting area in Northern Siberia, Russia.
Olga V. Karnachuk, Karnachuk, Olga V, Mancini, Stefano, Solioz, Marc, Helge K. Abicht, Marc Solioz, Stefano Mancini, Abicht, Helge K   +7 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source