Results 51 to 60 of about 80,951 (303)

A text-mining system for extracting metabolic reactions from full-text articles [PDF]

, 2012
Background: Increasingly biological text mining research is focusing on the extraction of complex relationships relevant to the construction and curation of biological networks and pathways. However, one important category of pathway—metabolic pathways—
Czarnecki, Jan M., Nobeli, Irene, Jan Czarnecki, Nobeli, Irilenia, Smith, Adrian M.L., Shepherd Adrian J, Irene Nobeli, Smith Adrian M, Shepherd, Adrian J., Czarnecki Jan, Nobeli Irene, Adrian J Shepherd, Adrian M Smith   +12 more
core   +1 more source

Targeted Large-Scale Genome Mining and Candidate Prioritization for Natural Product Discovery

Marine Drugs, 2022
Large-scale genome-mining analyses have identified an enormous number of cryptic biosynthetic gene clusters (BGCs) as a great source of novel bioactive natural products.
Jessie James Limlingan Malit, Hiu Yu Cherie Leung, Pei-Yuan Qian   +2 more
doaj   +1 more source

Data Mining of the Coffee Rust Genome [PDF]

, 2012
The genomes of nine isolates of _Hemileia vastatrix_, the causal agent of coffee leaf rust were sequenced by Illumina and 454. Quality control, cleaning and _de novo_ assemblies of data were performed.
Silvia Restrepo, David Octavio Botero-Rozo, Alvaro Gaitan, Diego M. Riaño-Pachon, Marco Cristancho, William Giraldo   +5 more
core   +2 more sources

How to Completely Squeeze a Fungus—Advanced Genome Mining Tools for Novel Bioactive Substances

Pharmaceutics, 2022
Fungal species have the capability of producing an overwhelming diversity of bioactive substances that can have beneficial but also detrimental effects on human health.
Andreas Schüller, Lena Studt-Reinhold, Joseph Strauss   +2 more
doaj   +1 more source

Web2.0 paves new ways for collaborative and exploratory analysis of Chemical Compounds in Spectrometry Data

Journal of Integrative Bioinformatics, 2011
In nowadays life science projects, sharing data and data interpretation is becoming increasingly important. This considerably calls for novel information technology approaches, which enable the integration of expert knowledge from different disciplines ...
Loyek Christian, Bunkowski Alexander, Vautz Wolfgang, Nattkemper Tim W.   +3 more
doaj   +1 more source

Mining Natural Product Biosynthesis in Eukaryotic Algae

Marine Drugs, 2020
Eukaryotic algae are an extremely diverse category of photosynthetic organisms and some species produce highly potent bioactive compounds poisonous to humans or other animals, most notably observed during harmful algal blooms.
Ellis O’Neill
doaj   +1 more source

Predicting the virulence of MRSA from its genome sequence [PDF]

, 2014
This work is supported by the EC-FP7 program no. 245500 and the BBSRCMicrobial virulence is a complex and often multifactorial phenotype, intricately linked to a pathogen's evolutionary trajectory.
Josefsson, Elisabet,, Hawkins, E., Josefsson, Elisabet, Holden, M., Yajjala, Vijaya Kumar, Feil, E. J., Read, T. D., Recker, Mario, Rudkin, Justine K., P. D. Fey, Z. Gulay, Kumar Yajjala, Vijaya, Wilson, D., E. J. Feil, Williams, P., T. Widhelm, Sloan, Tim J, Fey, P. D., Gulay, Zeynep, Parfett, S., Gulay, Z., Endres, Jennifer L, M. Recker, Priest, Nicholas K, Hurst, Laurence D, E. Josefsson, Lewis, K., Fey, Paul D, Sloan, Tim J., van den Elsen, J., M. Laabei, Peacock, Sharon J., Priest, Nicholas K., Feil, Edward J., Read, Timothy D., Aldeljawi, Mona, Parfett, Sara, J. K. Rudkin, L. Scowen, Hurst, Laurence D., P. Williams, Widhelm, Todd, S. Parfett, J. L. Endres, N. K. Priest, S. J. Peacock, Massey, R. C., Holden, Matthew, Peacock, Sharon J, J. van den Elsen, Bayles, Kenneth W., M. Holden, Massey, Ruth C., Scowen, L., Feil, Edward J, Rudkin, J. K., Hurst, L. D., E. Hawkins, M. Aldeljawi, Rudkin, Justine K, Read, Timothy D, K. W. Bayles, V. K. Yajjala, Wilson, Daniel, T. J. Sloan, L. D. Hurst, Recker, M., Aldeljawi, M., D. Wilson, Bayles, K. W., Laabei, Maisem, K. Lewis, Bayles, Kenneth W, Scowen, Lucy, Endres, J. L., Laabei, M., Hawkins, Erica, Yajjala, V. K., Williams, Paul, Sloan, T. J., Massey, Ruth C, Lewis, Katie, Endres, Jennifer L., Fey, Paul D., Peacock, S. J., Priest, N. K., van den Elsen, Jean, R. C. Massey, T. D. Read, Widhelm, T.   +89 more
core   +1 more source

Genome-Guided Investigation Provides New Insights into Secondary Metabolites of Streptomyces parvulus SX6 from Aegiceras corniculatum

Polish Journal of Microbiology, 2022
Whole-genome sequencing and genome mining are recently considered an efficient approach to shine more light on the underlying secondary metabolites of Streptomyces.
Quach Ngoc Tung, Nguyen Vu Thi Hanh, Bui Thi Lien, Pham Anh Tuan, An Nguyen Thi Thu, Xuan Le Thi Thanh, Thuy Ta Thi Thu, Dudhagara Pravin, Phi Quyet-Tien   +8 more
doaj   +1 more source

Mining the Genome for Therapeutic Targets [PDF]

Diabetes, 2017
Current pharmacological options for type 2 diabetes do not cure the disease. Despite the availability of multiple drug classes that modulate glycemia effectively and minimize long-term complications, these agents do not reverse pathogenesis, and in practice they are not selected to correct the molecular profile specific to the patient.
openaire   +2 more sources

An overview of interactive visual data mining techniques for knowledge discovery [PDF]

, 2013
n the past decade, the analysis of data has faced the challenge of dealing with very large and complex datasets and the real-time generation of data. Technologies to store and access these complex and large datasets are in place.
Gaber, Mohamed Medhat, Berendsen, M., Gabrys, Bogdan, Frederic Stahl, Stahl, F., Stahl, Frederic, Mohamed Medhat Gaber, Monika Berendsen, Gaber, M., Berendsen, Monika, Bogdan Gabrys, Gabrys, B.   +11 more
core   +1 more source