Results 31 to 40 of about 80,951 (303)

Marine-Derived Streptomyces sennicomposti GMY01 with Anti-Plasmodial and Anticancer Activities: Genome Analysis, In Vitro Bioassay, Metabolite Profiling, and Molecular Docking

Microorganisms, 2023
To discover novel antimalarial and anticancer compounds, we carried out a genome analysis, bioassay, metabolite profiling, and molecular docking of marine sediment actinobacteria strain GMY01. The whole-genome sequence analysis revealed that Streptomyces
Jaka Widada, Ema Damayanti, Mustofa Mustofa, Achmad Dinoto, Rifki Febriansah, Triana Hertiani   +5 more
doaj   +1 more source

Advanced Genomic Data Mining

PLoS Computational Biology, 2008
As data banks increase their size, one of the current challenges in bioinformatics is to be able to query them in a sensible way. Information is contained in different databases, with various data representations or formats, making it very difficult to use a single query tool to search more than a single data source.
Xosé M. Fernández-Suárez, Ewan Birney
openaire   +4 more sources

Genome Mining for Data Carpentry lesson [PDF]

, 2022
Data for Software Carpentry Genome Mining lesson. These data are part of the study "Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: Implications for the microbial pan-genome" (Hervé Tettelin et al ...
Selem-Mojica, Nelly, Ramos-García, Axel Alejandro   +1 more
core   +1 more source

Pseudomonassin, a New Bioactive Ribosomally Synthesised and Post-Translationally Modified Peptide from Pseudomonas sp. SST3

Microorganisms, 2023
Genome mining and metabolomics have become valuable tools in natural products research to evaluate and identify potential new chemistry from bacteria. In the search for new compounds from the deep-sea organism, Pseudomonas sp.
Kevin Jace Miranda, Saif Jaber, Dana Atoum, Subha Arjunan, Rainer Ebel, Marcel Jaspars, RuAngelie Edrada-Ebel   +6 more
doaj   +1 more source

Mining microbial genomes for new natural products and biosynthetic pathways [PDF]

, 2008
Analyses of microbial genome sequences have revealed numerous examples of ‘cryptic’ or ‘orphan’ biosynthetic gene clusters, with the potential to direct the production of novel, structurally complex natural products.
G. L. Challis, Challis, Gregory L.
core   +1 more source

Genome Mining for Software Carpentry lesson [PDF]

, 2022
Data for Software Carpentry Genome Mining lesson. These data are part of the study "Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: Implications for the microbial pan-genome" (Hervé Tettelin et al ...
Selem-Mojica, Nelly, Ramos-García, Axel Alejandro   +1 more
core   +1 more source

Application of massive parallel sequencing to whole genome SNP discovery in the porcine genome [PDF]

, 2009
Background Although the Illumina 1 G Genome Analyzer generates billions of base pairs of sequence data, challenges arise in sequence selection due to the varying sequence quality.
Kerstens Hindrik HD, Heuven, H.C.M., Johan T den Dunnen, Henri CM Heuven, Andreia J Amaral, den Dunnen Johan T, Dibbits Bert, Groenen Martien AM, Heuven Henri CM, Megens, H.J.W.C., Amaral Andreia J, Megens Hendrik-Jan, Bert Dibbits, Martien AM Groenen, Groenen, M.A.M., Hendrik-Jan Megens, Dibbits, B.W., Dungen, J., den, Kerstens, H.H.D., Hindrik HD Kerstens, Richard PMA Crooijmans, Crooijmans, R.P.M.A., den Dungen, J., Crooijmans Richard PMA, Amaral, A.J.   +24 more
core   +1 more source

Discovery of fungal onoceroid triterpenoids through domainless enzyme-targeted global genome mining [PDF]

, 2023
Genomics-guided methodologies have been widely adopted and proven beneficial for the discovery of natural products. However, a major challenge in the field of genome mining is determining how to selectively extract biosynthetic gene clusters (BGCs) for ...
Jia, Tang, Yudai, Matsuda
core   +1 more source

Computational Genomics of Specialized Metabolism: from Natural Product Discovery to Microbiome Ecology

mSystems, 2018
Microbial and plant specialized metabolites, also known as natural products, are key mediators of microbe-microbe and host-microbe interactions and constitute a rich resource for drug development.
Marnix H. Medema
doaj   +1 more source

Genome Mining Data of Bacillus cabrialesii TE3T [PDF]

, 2021
This dataset contains (1) the Bacillus cabrialesii TE3T genome, (2) the Bacillus cabrialesii TE3T genome-mining results and (3) results and BGC sequences used to construct BGC networking of Bacillus cabrialesii TE3T BGCs through BiG ...
Villa Rodríguez, E (via Mendeley Data)
core   +1 more source