Results 31 to 40 of about 72,600 (260)

Genome data mining for everyone

BMB Reports, 2008
The genomic sequences of a huge number of species have been determined. Typically, these genome sequences and the associated annotation data are accessed through Internet-based genome browsers that offer a user-friendly interface. Intelligent use of the data should expedite biological knowledge discovery.
Gir Won, Lee, Sangsoo, Kim
openaire   +3 more sources

Molecular Mapping of Reduced Plant Height Gene Rht24 in Bread Wheat

Frontiers in Plant Science, 2017
Height is an important trait related to plant architecture and yield potential in bread wheat (Triticum aestivum L.). We previously identified a major quantitative trait locus QPH.caas-6A flanked by simple sequence repeat markers Xbarc103 and Xwmc256 ...
Xiuling Tian, Xiuling Tian, Weie Wen, Weie Wen, Li Xie, Luping Fu, Dengan Xu, Chao Fu, Desen Wang, Xinmin Chen, Xianchun Xia, Xianchun Xia, Quanjia Chen, Zhonghu He, Zhonghu He, Shuanghe Cao   +15 more
doaj   +1 more source

Genomics-Driven Activation of Silent Biosynthetic Gene Clusters in Burkholderia gladioli by Screening Recombineering System

Molecules, 2021
The Burkholderia genus possesses ecological and metabolic diversities. A large number of silent biosynthetic gene clusters (BGCs) in the Burkholderia genome remain uncharacterized and represent a promising resource for new natural product discovery ...
Hanna Chen, Tao Sun, Xianping Bai, Jie Yang, Fu Yan, Lei Yu, Qiang Tu, Aiying Li, Yajie Tang, Youming Zhang, Xiaoying Bian, Haibo Zhou   +11 more
doaj   +1 more source

Targeted Large-Scale Genome Mining and Candidate Prioritization for Natural Product Discovery

Marine Drugs, 2022
Large-scale genome-mining analyses have identified an enormous number of cryptic biosynthetic gene clusters (BGCs) as a great source of novel bioactive natural products.
Jessie James Limlingan Malit, Hiu Yu Cherie Leung, Pei-Yuan Qian   +2 more
doaj   +1 more source

How to Completely Squeeze a Fungus—Advanced Genome Mining Tools for Novel Bioactive Substances

Pharmaceutics, 2022
Fungal species have the capability of producing an overwhelming diversity of bioactive substances that can have beneficial but also detrimental effects on human health.
Andreas Schüller, Lena Studt-Reinhold, Joseph Strauss   +2 more
doaj   +1 more source

Web2.0 paves new ways for collaborative and exploratory analysis of Chemical Compounds in Spectrometry Data

Journal of Integrative Bioinformatics, 2011
In nowadays life science projects, sharing data and data interpretation is becoming increasingly important. This considerably calls for novel information technology approaches, which enable the integration of expert knowledge from different disciplines ...
Loyek Christian, Bunkowski Alexander, Vautz Wolfgang, Nattkemper Tim W.   +3 more
doaj   +1 more source

Mining Natural Product Biosynthesis in Eukaryotic Algae

Marine Drugs, 2020
Eukaryotic algae are an extremely diverse category of photosynthetic organisms and some species produce highly potent bioactive compounds poisonous to humans or other animals, most notably observed during harmful algal blooms.
Ellis O’Neill
doaj   +1 more source

Genome-Guided Investigation Provides New Insights into Secondary Metabolites of Streptomyces parvulus SX6 from Aegiceras corniculatum

Polish Journal of Microbiology, 2022
Whole-genome sequencing and genome mining are recently considered an efficient approach to shine more light on the underlying secondary metabolites of Streptomyces.
Quach Ngoc Tung, Nguyen Vu Thi Hanh, Bui Thi Lien, Pham Anh Tuan, An Nguyen Thi Thu, Xuan Le Thi Thanh, Thuy Ta Thi Thu, Dudhagara Pravin, Phi Quyet-Tien   +8 more
doaj   +1 more source

Mining the Genome for Therapeutic Targets [PDF]

Diabetes, 2017
Current pharmacological options for type 2 diabetes do not cure the disease. Despite the availability of multiple drug classes that modulate glycemia effectively and minimize long-term complications, these agents do not reverse pathogenesis, and in practice they are not selected to correct the molecular profile specific to the patient.
openaire   +2 more sources

Genome Mining of Chryseobacterium proteolyticum for Keratinolytic Properties and Prospective Applications

Journal of Pure and Applied Microbiology
The manipulation of keratinolytic determinants provides an avenue for enhancing keratinase output, thereby facilitating the conversion of wasted chicken feathers into valuable products.
Lindelwa Mpaka, Nonso E. Nnolim, Uchechukwu U. Nwodo   +2 more
doaj   +1 more source